Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Samuel J, Hobbs"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Tissue-resident memory (TRM) CD8+ T cells are largely derived from recently activated effector T cells, but the mechanisms that control the extent of TRM differentiation within tissue microenvironments remain unresolved. Here, using an IFNγ
Externí odkaz:
https://doaj.org/article/98659d4192e840ac935c48162957b947
Autor:
Samuel J. Hobbs, Jeffrey C. Nolz
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 2990-2997.e2 (2019)
Summary: Tissue-resident memory (TRM) CD8+ T cells are positioned within environmental barrier tissues to provide a first line of defense against pathogen entry, but whether these specialized T cell populations can be readily boosted to increase prot
Externí odkaz:
https://doaj.org/article/a4cf61dba11045efa8bdec4e80349954
Autor:
Azita Leavitt, Erez Yirmiya, Gil Amitai, Allen Lu, Jeremy Garb, Ehud Herbst, Benjamin R. Morehouse, Samuel J. Hobbs, Sadie P. Antine, Zhen-Yu J. Sun, Philip J. Kranzusch, Rotem Sorek
Publikováno v:
Nature. 611:326-331
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6752fba33f0abd013e5a97d55de9c67e
https://doi.org/10.1038/s41586-022-05375-9
https://doi.org/10.1038/s41586-022-05375-9
Autor:
Jossef F Osborn, Samuel J Hobbs, Jana L Mooster, Tahsin N Khan, Augustus M Kilgore, Jake C Harbour, Jeffrey C Nolz
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007633 (2019)
Memory CD8+ T cells in the circulation rapidly infiltrate non-lymphoid tissues following infection and provide protective immunity in an antigen-specific manner. However, the subsequent fate of memory CD8+ T cells after entering non-lymphoid tissues
Externí odkaz:
https://doaj.org/article/3d83680066fd4304be459b61fd72a3bb
Autor:
Desmond Richmond-Buccola, Samuel J. Hobbs, Jasmine M. Garcia, Hunter Toyoda, Jingjing Gao, Sichen Shao, Amy S. Y. Lee, Philip J. Kranzusch
Publikováno v:
bioRxiv
SUMMARYCBASS is an anti-phage defense system that protects bacteria from phage infection and is evolutionarily related to human cGAS-STING immunity. cGAS-STING signaling is initiated by viral DNA but the stage of phage replication which activates bac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d195f8e344297289a731e60abc79f44
https://doi.org/10.1101/2023.05.21.541620
https://doi.org/10.1101/2023.05.21.541620
Autor:
Samuel J. Hobbs, Tanita Wein, Allen Lu, Benjamin R. Morehouse, Julia Schnabel, Azita Leavitt, Erez Yirmiya, Rotem Sorek, Philip J. Kranzusch
Publikováno v:
Nature. 605:522-526
The cyclic oligonucleotide-based antiphage signalling system (CBASS) and the pyrimidine cyclase system for antiphage resistance (Pycsar) are antiphage defence systems in diverse bacteria that use cyclic nucleotide signals to induce cell death and pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e229f1616e7c4b0cb02f1769e9d842ac
https://doi.org/10.1038/s41586-022-04716-y
https://doi.org/10.1038/s41586-022-04716-y
Autor:
Samuel J. Hobbs, Jeffrey C. Nolz
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Selectins constitute a family of oligosaccharide binding proteins that play critical roles in regulating the trafficking of leukocytes. In T cells, L-selectin (CD62L) controls the capacity for naive and memory T cells to actively survey peripheral ly
Externí odkaz:
https://doaj.org/article/13daa38c3e274575b3de0ef81a7253e5
Autor:
Andrew Frando, Kyu Y. Rhee, Tige R. Rustad, David R. Sherman, Samuel J. Hobbs, Neil David Fleck, Christoph Grundner, Vijay Soni, Robert Morrison, Jessica Farrow-Johnson, Shuyi Ma
Publikováno v:
Nature microbiology
Transposon-based strategies provide a powerful and unbiased way to study the bacterial stress response1-8, but these approaches cannot fully capture the complexities of network-based behaviour. Here, we present a network-based genetic screening appro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd91b52555380ac1e0621784f010e8d
https://doi.org/10.1038/s41564-020-00810-x
https://doi.org/10.1038/s41564-020-00810-x
Publikováno v:
Current Opinion in Virology. 28:12-19
Epicutaneous delivery of vaccinia virus (VacV) by scarification of the skin generates robust and durable protective immunity, which was ultimately responsible for eradicating smallpox from the human race. Therefore, infection of the skin with VacV is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edc6e3123170e1c11eb7bf1f1ad3871c
https://doi.org/10.1016/j.coviro.2017.10.001
https://doi.org/10.1016/j.coviro.2017.10.001
Autor:
Scott J. Edmundson, Samuel J. Hobbs, A. Chavis, Michael H. Huesemann, Mark S. Wigmosta, Ning Sun, D. Rye
Publikováno v:
Journal of Applied Phycology. 30:287-298
Chlorella sorokiniana (DOE 1412) emerged as one of the most promising microalgae strains from the NAABB consortium project and was found to have a remarkable doubling time under optimal conditions of 2.57 h−1. However, its maximum achievable annual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aea184b36ae248530a1acced12d29340
https://doi.org/10.1007/s10811-017-1256-6
https://doi.org/10.1007/s10811-017-1256-6