Zobrazeno 1 - 10
of 328
pro vyhledávání: '"Samuel Huber"'
Autor:
Christoph Kilian, Hanna Ulrich, Viktor A. Zouboulis, Paulina Sprezyna, Jasmin Schreiber, Tomer Landsberger, Maren Büttner, Moshe Biton, Eduardo J. Villablanca, Samuel Huber, Lorenz Adlung
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Single-cell-based methods such as flow cytometry or single-cell mRNA sequencing (scRNA-seq) allow deep molecular and cellular profiling of immunological processes. Despite their high throughput, however, these measurements represent only a s
Externí odkaz:
https://doaj.org/article/dfc656f64e754da59ca2a0d5aea18f89
Autor:
Daria Krzikalla, Alena Laschtowitz, Lisa Leypoldt, Cornelia Gottwick, Pia Averhoff, Sören Weidemann, Ansgar W. Lohse, Samuel Huber, Christoph Schramm, Dorothee Schwinge, Johannes Herkel, Antonella Carambia
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 1, Pp 79-91 (2024)
Background & Aims: The liver has a distinct capacity to induce immune tolerance to hepatic antigens. Although liver tolerance can be advantageous for preventing autoimmune and inflammatory diseases, it also can be detrimental by preventing immune sur
Externí odkaz:
https://doaj.org/article/5bdb57d96fae45dab3880fcdea472873
Autor:
Lorenz Kocheise, Martin Schoenlein, Berit Behrends, Vincent Joerg, Christian Casar, Thorben W. Fruendt, Thomas Renné, Asmus Heumann, Jun Li, Samuel Huber, Ansgar W. Lohse, Klaus Pantel, Sabine Riethdorf, Henning Wege, Kornelius Schulze, Johann von Felden
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Hepatocellular carcinoma (HCC) has high recurrence rates exceeding 50% despite curative resection. The serum biomarker alpha-fetoprotein (AFP) is a well-known prognostic marker for HCC. EpCAM-positive circulating tumor cells (CTC) have a hig
Externí odkaz:
https://doaj.org/article/15b7e984aa6d4635b4ab35ffa9783014
Autor:
Thomas Theo Brehm, Andreas Heyer, Marcel S. Woo, Marlene Fischer, Marc van der Meirschen, Dominic Wichmann, Dominik Jarczak, Kevin Roedl, Stefan Schmiedel, Marylyn M. Addo, Marc Lütgehetmann, Martin Christner, Samuel Huber, Ansgar W. Lohse, Stefan Kluge, Julian Schulze zur Wiesch
Publikováno v:
Journal of Infection and Public Health, Vol 16, Iss 11, Pp 1806-1812 (2023)
Background: Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, the roll-out of vaccines and therapeutic agents, as well as the emergence of novel SARS-CoV-2 variants, have shown significant effects on disease severity. Methods:
Externí odkaz:
https://doaj.org/article/efa2ba5d37094146a5932b908907dff7
Autor:
Tonina T. Mueller, Mona Pilartz, Manovriti Thakur, Torben LangHeinrich, Junfu Luo, Rebecca Block, Jonathan K.L. Hoeflinger, Sarah Meister, Flavio Karaj, Laura Garcia Perez, Rupert Öllinger, Thomas Engleitner, Jakob Thoss, Michael Voelkl, Claudia Tersteeg, Uwe Koedel, Alexander Zigman Kohlmaier, Daniel Teupser, Malgorzata Wygrecka, Haifeng Ye, Klaus T. Preissner, Helena Radbruch, Sefer Elezkurtaj, Matthias Mack, Philipp von Hundelshausen, Christian Weber, Steffen Massberg, Christian Schulz, Roland Rad, Samuel Huber, Hellen Ishikawa-Ankerhold, Bernd Engelmann
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Innate myeloid cells especially neutrophils and their extracellular traps are known to promote intravascular coagulation and thrombosis formation in infections and various other conditions. Innate myeloid cell dependent fibrin formation can support s
Externí odkaz:
https://doaj.org/article/4839f9e3a00e42f59cb668d05a73ce41
Autor:
Tao Zhang, Philipp Seeger, Yashin Simsek, Morsal Sabihi, Jöran Lücke, Dimitra E. Zazara, Ahmad Mustafa Shiri, Jan Kempski, Tom Blankenburg, Lilan Zhao, Ioannis Belios, Andres Machicote, Baris Mercanoglu, Mohammad Fard-Aghaie, Sara Notz, Panagis M. Lykoudis, Marius Kemper, Tarik Ghadban, Oliver Mann, Thilo Hackert, Jakob R. Izbicki, Thomas Renné, Samuel Huber, Anastasios D. Giannou, Jun Li
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27578- (2024)
Background: Insufficient remnant liver volume (RLV) after the resection of hepatic malignancy could lead to liver failure and mortality. Portal vein ligation (PVL) prior to hepatectomy is subsequently introduced to increase the remnant liver volume a
Externí odkaz:
https://doaj.org/article/e149ef093eb041cda71966c12d3904a4
Autor:
Friederike Stumme, Niklas Steffens, Babett Steglich, Franziska Mathies, Mikolaj Nawrocki, Morsal Sabihi, Shiwa Soukou-Wargalla, Emilia Göke, Jan Kempski, Thorben Fründt, Sören Weidemann, Christoph Schramm, Nicola Gagliani, Samuel Huber, Tanja Bedke
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPrimary sclerosing cholangitis (PSC) is a chronic liver disease marked by inflammation of the bile ducts and results in the development of strictures and fibrosis. A robust clinical correlation exists between PSC and inflammatory bowel dise
Externí odkaz:
https://doaj.org/article/fe4be545b6ce4708b789790c53a8eb4c
Autor:
Jöran Lücke, Tao Zhang, Dimitra E. Zazara, Philipp Seeger, Jacob R. Izbicki, Thilo Hackert, Samuel Huber, Anastasios D. Giannou
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102696- (2024)
Summary: Forced metastasis models, those in which the step of intravasation is bypassed, can be used to investigate the mechanisms underlying metastasis and evaluate potential therapeutic targets. Here, we present a protocol for using three forced mo
Externí odkaz:
https://doaj.org/article/78ee8a0a58484099b0a3af90da86297a
Autor:
Jöran Lücke, Baris Mercanoglu, Tao Zhang, Dimitra E. Zazara, Ehud Zigmond, Philipp Seeger, Oliver Mann, Jakob R. Izbicki, Thilo Hackert, Samuel Huber, Anastasios D. Giannou
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102811- (2024)
Summary: To investigate underlying mechanisms for cancer metastasis and promising therapies in animal models, spontaneous metastasis models can be used to recreate metastasis development. Here, we present three mouse models of spontaneous lung and/or
Externí odkaz:
https://doaj.org/article/b0d3589269ad491faed94e797c760565
Autor:
Fabian Hausmann, Can Ergen, Robin Khatri, Mohamed Marouf, Sonja Hänzelmann, Nicola Gagliani, Samuel Huber, Pierre Machart, Stefan Bonn
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-40 (2023)
Abstract Background Single-cell sequencing provides detailed insights into biological processes including cell differentiation and identity. While providing deep cell-specific information, the method suffers from technical constraints, most notably a
Externí odkaz:
https://doaj.org/article/a37a7fd8e5294ea4979af75cc27ceea2