Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Samuel Hellings"'
Autor:
Amit Anand, Samuel Hellings, Shilpa Garg, Julius Punnen, U M Nagamalesh, Sabariya Selvam, Bagirath Raghuraman, Onkar Date, Senthil Kumaran, Pradeep Narayan, Ankita Udwadia, David A Gordon, Lei Zhao, Jyoti Gulia
Publikováno v:
Circulation Research. 131
Heart failure (HF) is a leading cause of death worldwide and research focused on human cardiac tissue provides insights into underlying disease mechanisms. In this study, we performed transcriptome analyses on cardiac tissue from 21 South Asian (SA)
Autor:
Claudia Generaux, Heather Finlay, Susan R. Arthur, Mei-Yin Hsu, Roy Haskell, Peter S. Gargalovic, Joelle M. Onorato, Michael Basso, Rongan Zhang, Kimberley A. Lentz, Anne Rose, Carrie Xu, Lei Zhao, Jeffrey S. Bostwick, Gayani Fernando, Ricardo Garcia, Xue-Qing Chen, James Hennan, Michael C. Myers, R. Michael Lawrence, Petia Shipkova, Samuel Hellings
Publikováno v:
Analytical Biochemistry. 568:41-50
Apelin, the endogenous ligand for the APJ receptor, has generated interest due to its beneficial effects on the cardiovascular system. Synthesized as a 77 amino acid preproprotein, apelin is post-translationally cleaved to a series of shorter peptide
Autor:
Elizabeth Brown, Azza Karrar, Samuel Hellings, Maria Stepanova, Bethane Warrack, Brian Lam, Joelle Onorato, Sean Felix, Abraham Apfel, Thomas Jeffers, Bijal Rajput, Edgar Charles, Fatema Nader, Yi Luo, Michael Reily, Lei Zhao, John Thompson, Zachary Goodman, Zobair Younossi
Publikováno v:
Journal of Hepatology. 73:S409-S410
Autor:
Mary Ellen Cvijic, Elizabeth Brown, Sean Felix, Edgar D. Charles, Thomas E. Spires, Mette Juul Nielsen, Diana Julie Leeming, Sumanta Mukherjee, Brian Lam, Natasja Stæhr Gudmann, Zobair M. Younossi, Thomas Jeffers, Maria Stepanova, Melissa Yarde, Morten A. Karsdal, Samuel Hellings, Leonid Zhelnin, Bijal Rajput, Yi Luo, Anthony Sanfiz, Azza Karrar, David L. Gordon, Zachary Goodman, Lei Zhao, Fatema Nader
Publikováno v:
Gastroenterology. 158:S-1293
Autor:
Joelle M, Onorato, Carrie, Xu, Xue-Qing, Chen, Anne V, Rose, Claudia, Generaux, Kimberley, Lentz, Petia, Shipkova, Susan, Arthur, James K, Hennan, Roy, Haskell, Michael C, Myers, R Michael, Lawrence, Heather J, Finlay, Michael, Basso, Jeffrey, Bostwick, Gayani, Fernando, Ricardo, Garcia, Samuel, Hellings, Mei-Yin, Hsu, Rongan, Zhang, Lei, Zhao, Peter, Gargalovic
Publikováno v:
Analytical biochemistry. 568
Apelin, the endogenous ligand for the APJ receptor, has generated interest due to its beneficial effects on the cardiovascular system. Synthesized as a 77 amino acid preproprotein, apelin is post-translationally cleaved to a series of shorter peptide
Autor:
David L. Gordon, Zachary Goodman, Mary Ellen Cvijic, Edgar D. Charles, Fatema Nader, Gabor Jarai, Elizabeth Brown, Samuel Hellings, Anthony Sanfiz, Sean Felix, Maria Stepanova, Zobair M. Younossi, Thomas E. Spires, Brian Lam, Lei Zhao, Melissa Yarde, Leonid Zhelnin, Azza Karrar, Sumanta Mukherjee, Thomas Jeffers, Yi Luo
Publikováno v:
Journal of Hepatology. 70:e787
Autor:
Debra Search, Huaping Tang, Mujing Yan, Ricardo Garcia, Nancy L. Carson, Joseph E. Dinchuk, Constance Smith-Monroy, Yan Kong, Rongan Zhang, David A. Gordon, Jian Chen, Carol S. Ryan, Peter S. Gargalovic, George C. Psaltis, Judith Wardwell-Swanson, Joanna Zheng, Samuel Hellings, Peter W. Glunz
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111385 (2014)
PLoS ONE
PLoS ONE
BACKGROUND: P2Y(6), a purinergic receptor for UDP, is enriched in atherosclerotic lesions and is implicated in pro-inflammatory responses of key vascular cell types and macrophages. Evidence for its involvement in atherogenesis, however, has been lac
Autor:
Robert Langish, David A. Gordon, Wen-Pin Yang, Thomas Harrity, Carol S. Ryan, Mujing Yan, Jeffrey A. Robl, Bo Guan, Linda Watson, Nancy L. Carson, Aiqing He, George C. Psaltis, Joseph R. Taylor, Richard Yang, Rongan Zhang, Jian Chen, Petia Shipkova, Amy Truong, Peter S. Gargalovic, Samuel Hellings, Jacek Ostrowski, Debra Search, Ricardo Garcia, John A. Lupisella
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e53192 (2013)
PLoS ONE
PLoS ONE
BACKGROUND: Chronic glucocorticoid excess has been linked to increased atherosclerosis and general cardiovascular risk in humans. The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) increases active glucocorticoid levels within tissues by
Autor:
Kathleen H. Young, Samuel Hellings, Mita Modi, Stephen S. Lin, Brad Ozenberger, Rodrigo Franco, Morris Husbands, Lucy Sun, Eunice Lee
Publikováno v:
Nature biotechnology. 16(10)
The interaction of the N-type calcium channel beta3 subunit with the alpha1B subunit alters the activation/inactivation kinetics and the maximal conductance of the channel. The defined protein-protein interaction of the human alpha1B and beta3 subuni