Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Samuel H. Berman"'
Autor:
Jorge S. Reis-Filho, Paul Cottu, Britta Weigelt, Brigitte Sigal, Larry Norton, Agnes Viale, Anne Vincent-Salomon, Jean-Yves Pierga, Lu Wang, Samuel H. Berman, Fresia Pareja, Ronglai Shen, Ino de Bruijn, Raymond S. Lim, Felipe C. Geyer, Salvatore Piscuoglio, Francois-Clement Bidard, Charlotte K.Y. Ng
Supplementary Fig. S3: Evolution of mutational signatures in treatment-naïve patients with de novo synchronous metastatic breast cancer. (A) Heatmap represents the similarity of the observed mutational signatures (blue, see color key) to those pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b098e2c7befba088a1dad0548f07cd
https://doi.org/10.1158/1078-0432.22468658
https://doi.org/10.1158/1078-0432.22468658
Autor:
Jorge S. Reis-Filho, Paul Cottu, Britta Weigelt, Brigitte Sigal, Larry Norton, Agnes Viale, Anne Vincent-Salomon, Jean-Yves Pierga, Lu Wang, Samuel H. Berman, Fresia Pareja, Ronglai Shen, Ino de Bruijn, Raymond S. Lim, Felipe C. Geyer, Salvatore Piscuoglio, Francois-Clement Bidard, Charlotte K.Y. Ng
Purpose: Paired primary breast cancers and metachronous metastases after adjuvant treatment are reported to differ in their clonal composition and genetic alterations, but it is unclear whether these differences stem from the selective pressures of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d46fd7f554287959162fe07a816aad1
https://doi.org/10.1158/1078-0432.c.6527021.v1
https://doi.org/10.1158/1078-0432.c.6527021.v1
Autor:
Jorge S. Reis-Filho, Paul Cottu, Britta Weigelt, Brigitte Sigal, Larry Norton, Agnes Viale, Anne Vincent-Salomon, Jean-Yves Pierga, Lu Wang, Samuel H. Berman, Fresia Pareja, Ronglai Shen, Ino de Bruijn, Raymond S. Lim, Felipe C. Geyer, Salvatore Piscuoglio, Francois-Clement Bidard, Charlotte K.Y. Ng
Supplementary Table S1: Clinicopathologic characteristics of breast cancer patients with de novo metastastic disease included in the study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34966351bfaf8f5531fda2ada4afaf9e
https://doi.org/10.1158/1078-0432.22468652
https://doi.org/10.1158/1078-0432.22468652
Autor:
Jorge S. Reis-Filho, Paul Cottu, Britta Weigelt, Brigitte Sigal, Larry Norton, Agnes Viale, Anne Vincent-Salomon, Jean-Yves Pierga, Lu Wang, Samuel H. Berman, Fresia Pareja, Ronglai Shen, Ino de Bruijn, Raymond S. Lim, Felipe C. Geyer, Salvatore Piscuoglio, Francois-Clement Bidard, Charlotte K.Y. Ng
Supplementary Table S2: Genomic analyses performed for the samples analyzed in the study and validation rates of mutations identified by whole�exome sequencing and Validation of mutations identified by whole�exome sequencing using targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063acde2f566ae20bffeb5b7becf54e1
https://doi.org/10.1158/1078-0432.22468649
https://doi.org/10.1158/1078-0432.22468649
Autor:
Cathy B. Moelans, Paul J. van Diest, Britta Weigelt, Jorge S. Reis-Filho, Samuel H. Berman, Salvatore Piscuoglio, Kathleen A. Burke, Charlotte K.Y. Ng, Ju Youn Lee, Pier Selenica, Willemijne A.M.E. Schrijver
Supplementary Table S1. Clinico-pathologic characteristics of primary breast cancers from our series and the METABRIC study and comparative analyses of the frequencies of somatic mutations found in the 341 genes analyzed. Supplementary Table S2. TP53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192c3cacca7349038197cd8918be14e7
https://doi.org/10.1158/0008-5472.22415856.v1
https://doi.org/10.1158/0008-5472.22415856.v1
Autor:
Jorge S. Reis-Filho, Paul Cottu, Britta Weigelt, Brigitte Sigal, Larry Norton, Agnes Viale, Anne Vincent-Salomon, Jean-Yves Pierga, Lu Wang, Samuel H. Berman, Fresia Pareja, Ronglai Shen, Ino de Bruijn, Raymond S. Lim, Felipe C. Geyer, Salvatore Piscuoglio, Francois-Clement Bidard, Charlotte K.Y. Ng
Supplementary Fig. S2: Repertoire of somatic mutations found in the biopsies of primary breast cancers and their metastatic lesions in the nine treatment-naïve patients with de novo synchronous metastatic breast cancer. (A) Heatmaps indicate the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56dd81c33a64c25771bc1f156d456afa
https://doi.org/10.1158/1078-0432.22468661.v1
https://doi.org/10.1158/1078-0432.22468661.v1
Autor:
Jorge S. Reis-Filho, Paul Cottu, Britta Weigelt, Brigitte Sigal, Larry Norton, Agnes Viale, Anne Vincent-Salomon, Jean-Yves Pierga, Lu Wang, Samuel H. Berman, Fresia Pareja, Ronglai Shen, Ino de Bruijn, Raymond S. Lim, Felipe C. Geyer, Salvatore Piscuoglio, Francois-Clement Bidard, Charlotte K.Y. Ng
PDF file containing the Supplementary Methods and Supplementary References.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd420813bd90d1a42f490b407d0afc3f
https://doi.org/10.1158/1078-0432.22468655.v1
https://doi.org/10.1158/1078-0432.22468655.v1
Autor:
Jorge S. Reis-Filho, Paul Cottu, Britta Weigelt, Brigitte Sigal, Larry Norton, Agnes Viale, Anne Vincent-Salomon, Jean-Yves Pierga, Lu Wang, Samuel H. Berman, Fresia Pareja, Ronglai Shen, Ino de Bruijn, Raymond S. Lim, Felipe C. Geyer, Salvatore Piscuoglio, Francois-Clement Bidard, Charlotte K.Y. Ng
Supplementary Table S3: Lists of validated somatic single nucleotide variants/ insertions and deletions, and amplifications/ homozygous deletions in the therapy-naïve synchronous primary and metastatic breast cancers studied.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981f8ff13e3d37fa58cd9bc028915584
https://doi.org/10.1158/1078-0432.22468646.v1
https://doi.org/10.1158/1078-0432.22468646.v1
Autor:
Cathy B. Moelans, Paul J. van Diest, Britta Weigelt, Jorge S. Reis-Filho, Samuel H. Berman, Salvatore Piscuoglio, Kathleen A. Burke, Charlotte K.Y. Ng, Ju Youn Lee, Pier Selenica, Willemijne A.M.E. Schrijver
A. Correlations between concordance percentage of mutations and time between primary tumor and paired metastases B. Influence of different adjuvant treatments on percentage of concordant, primary only or metastasis only mutations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631fa68e4aaf6558b9c68ba3dfa9760d
https://doi.org/10.1158/0008-5472.22415859.v1
https://doi.org/10.1158/0008-5472.22415859.v1
Autor:
Jorge S. Reis-Filho, Paul Cottu, Britta Weigelt, Brigitte Sigal, Larry Norton, Agnes Viale, Anne Vincent-Salomon, Jean-Yves Pierga, Lu Wang, Samuel H. Berman, Fresia Pareja, Ronglai Shen, Ino de Bruijn, Raymond S. Lim, Felipe C. Geyer, Salvatore Piscuoglio, Francois-Clement Bidard, Charlotte K.Y. Ng
Supplementary Table S4: Pathway analysis of genes with mutations enriched in the metastasis or associated with loss of heterozygosity (LOH) in the metastasis using Ingenuity Pathway Analysis and g:Profiler.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a7ad7b90dc5d84a1ba9024f39666edb
https://doi.org/10.1158/1078-0432.22468643
https://doi.org/10.1158/1078-0432.22468643