Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Samuel Grindel"'
Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism
Autor:
Michael Landowski, Vijesh J. Bhute, Samuel Grindel, Zachary Haugstad, Yeboah K. Gyening, Madison Tytanic, Richard S. Brush, Lucas J. Moyer, David W. Nelson, Christopher R. Davis, Chi-Liang Eric Yen, Sakae Ikeda, Martin-Paul Agbaga, Akihiro Ikeda
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Lipid analysis of transmembrane protein 135 (TMEM135) mutant mice reveals robust decreases in docosahexaenoic acid (DHA), indicating a function of TMEM135 on the export of DHA from peroxisomes that is important for maintaining lipid metabolism.
Externí odkaz:
https://doaj.org/article/aac097ba34414892882b668cb0412247
Autor:
Michael Landowski, Vijesh J. Bhute, Tetsuya Takimoto, Samuel Grindel, Pawan K. Shahi, Bikash R. Pattnaik, Sakae Ikeda, Akihiro Ikeda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Aging is a significant factor in the development of age-related diseases but how aging disrupts cellular homeostasis to cause age-related retinal disease is unknown. Here, we further our studies on transmembrane protein 135 (Tmem135), a gene
Externí odkaz:
https://doaj.org/article/d633aa25577040809a8ae0d6a88ae590
Autor:
Nicholas J. Hess, Payton N. Lindner, Jessica Vazquez, Samuel Grindel, Amy W. Hudson, Aleksandar K. Stanic, Akihiro Ikeda, Peiman Hematti, Jenny E. Gumperz
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
NBSGW mice are highly immunodeficient and carry a hypomorphic mutation in the c-kit gene, providing a host environment that supports robust human hematopoietic expansion without pre-conditioning. These mice thus provide a model to investigate human h
Externí odkaz:
https://doaj.org/article/4c3bb1cca1d24553988c74833d7ba044
Autor:
Akihiro Ikeda, Catherine Bowes Rickman, Sakae Ikeda, Ying Hao, Samuel Grindel, Michael Landowski
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08016b6e211999681d713f822c4b7a32
https://doi.org/10.3791/64927
https://doi.org/10.3791/64927
Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism
Autor:
Michael Landowski, Vijesh J. Bhute, Samuel Grindel, Zachary Haugstad, Yeboah K. Gyening, Madison Tytanic, Richard S. Brush, Lucas J. Moyer, David W. Nelson, Christopher R. Davis, Chi-Liang Eric Yen, Sakae Ikeda, Martin-Paul Agbaga, Akihiro Ikeda
Publikováno v:
Communications biology. 6(1)
Transmembrane protein 135 (TMEM135) is thought to participate in the cellular response to increased intracellular lipids yet no defined molecular function for TMEM135 in lipid metabolism has been identified. In this study, we performed a lipid analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f982cd2b59417743ec284892e440c347
https://pubmed.ncbi.nlm.nih.gov/36599953
https://pubmed.ncbi.nlm.nih.gov/36599953
Autor:
Michael Landowski, Vijesh J. Bhute, Tetsuya Takimoto, Samuel Grindel, Pawan K. Shahi, Bikash R. Pattnaik, Sakae Ikeda, Akihiro Ikeda
Publikováno v:
Scientific Reports
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Aging is a significant factor in the development of age-related diseases but how aging disrupts cellular homeostasis to cause age-related retinal disease is unknown. Here, we further our studies on transmembrane protein 135 (Tmem135), a gene involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1e9be1f5e743c421ae0a1a7760d938
https://pubmed.ncbi.nlm.nih.gov/35031662
https://pubmed.ncbi.nlm.nih.gov/35031662
Autor:
Franky Shi, Daniel Western, Abigail Johnson, Wei-Hua Lee, Adrienne Race, Bikash R. Pattnaik, Evelyn Santoirre, Pawan K Shahi, Jonathan Benson, Akihiro Ikeda, Michael Landowski, Sakae Ikeda, Samuel Grindel, Marvin Gao
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Aging is a critical risk factor for the development of retinal diseases, but how aging perturbs ocular homeostasis and contributes to disease is unknown. We identified transmembrane protein 135 (Tmem135) as a gene important for regulating ret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4edcdbb8810c68cb1eb415c959eb80
http://europepmc.org/articles/PMC7581492
http://europepmc.org/articles/PMC7581492
Autor:
Samuel Grindel, Amy W. Hudson, Jessica Vazquez, Peiman Hematti, Akihiro Ikeda, Nicholas J Hess, Payton N. Lindner, Jenny E. Gumperz, Aleksandar K. Stanic
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
NBSGW mice are highly immunodeficient and carry a hypomorphic mutation in the c-kit gene, providing a host environment that supports robust human hematopoietic expansion without pre-conditioning. These mice thus provide a model to investigate human h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46150e32c17ea4d9faa03ba0b3de178f
https://pubmed.ncbi.nlm.nih.gov/33193358
https://pubmed.ncbi.nlm.nih.gov/33193358