Data from Phase Ib/II Dose Expansion Study of Lenvatinib Combined with Letrozole in Postmenopausal Women with Hormone Receptor–Positive Breast Cancer

Autor: Soo-Chin Lee, Boon Cher Goh, Bee Choo Tai, Lingzhi Wang, Supriya Jain, Kritika Yadav, Raghav Sundar, Cheng Ean Chee, David S.P. Tan, Ross A. Soo, Wei Peng Yong, Hon Lyn Tan, Joan R.E. Choo, Matilda Lee, Yi Wan Lim, Siew Eng Lim, Wan Qin Chong, Yvonne L.E. Ang, Gloria H.J. Chan, Natalie Y.L. Ngoi, Samuel G.W. Ow, Andrea L.A. Wong, Joline S.J. Lim

Purpose:RET is an estrogen response gene with preclinical studies demonstrating cross-talk between the RET and estrogen receptor (ER) pathways. We investigate the role of lenvatinib, a multikinase inhibitor with potent activity against RET, in patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e493f677e970d70092bf8afa81bf17c
https://doi.org/10.1158/1078-0432.c.6532424.v1

Supplementary Data from Phase Ib/II Dose Expansion Study of Lenvatinib Combined with Letrozole in Postmenopausal Women with Hormone Receptor–Positive Breast Cancer

Autor: Soo-Chin Lee, Boon Cher Goh, Bee Choo Tai, Lingzhi Wang, Supriya Jain, Kritika Yadav, Raghav Sundar, Cheng Ean Chee, David S.P. Tan, Ross A. Soo, Wei Peng Yong, Hon Lyn Tan, Joan R.E. Choo, Matilda Lee, Yi Wan Lim, Siew Eng Lim, Wan Qin Chong, Yvonne L.E. Ang, Gloria H.J. Chan, Natalie Y.L. Ngoi, Samuel G.W. Ow, Andrea L.A. Wong, Joline S.J. Lim

Supplementary Data from Phase Ib/II Dose Expansion Study of Lenvatinib Combined with Letrozole in Postmenopausal Women with Hormone Receptor–Positive Breast Cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00fc277da44ab4288b38054c7a7e0c6
https://doi.org/10.1158/1078-0432.22486946

Supplementary Data from Phase I Trial of Expanded, Activated Autologous NK-cell Infusions with Trastuzumab in Patients with HER2-positive Cancers

Autor: Dario Campana, Boon Cher Goh, Priscillia J.X. Koe, Jedidah L.M. Lieow, Nesaretnam Barr Kumarakulasinghe, Wan Qin Chong, Hon Lyn Tan, Raghav Sundar, Elaine Coustan-Smith, Mabel Z.Q. Foo, Yoon Sim Yap, Lavina Bharwani, Samuel G.W. Ow, Sing Huang Tan, Michelle L.M. Poon, Liang Piu Koh, Lip Kun Tan, Wei Peng Yong, Kritika Yadav, Andrea Wong, Joline S.J. Lim, Noriko Shimasaki, Soo-Chin Lee

Supplementary Materials, Figures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0209f96b4c5f79fd3d29bd1e4c30823
https://doi.org/10.1158/1078-0432.22478064

Clinical genetic testing outcome with multi-gene panel in Asian patients with multiple primary cancers

Autor: Siew Eng Lim, Yi Wan Lim, Jeffrey Low, Samuel Guan Wei Ow, Soo-Chin Lee, Pei Yi Ong, Hwai Loong Kong, David S.P. Tan, Gloria Chan

Publikováno v: Oncotarget

// Gloria H.J. Chan 1, * , Pei Yi Ong 1, * , Jeffrey J.H. Low 2 , Hwai Loong Kong 1 , Samuel G.W. Ow 1 , David S.P. Tan 1, 3 , Yi Wan Lim 1 , Siew Eng Lim 1 and Soo-Chin Lee 1, 3 1 Department of Haematology-Oncology, National University Cancer Instit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1878192db94f27fd027543b34803aed1
https://pubmed.ncbi.nlm.nih.gov/30093976

Reversal of Bowel Obstruction With Platinum-Based Chemotherapy and Olaparib in Recurrent, Short Platinum-Free Interval, RAD51C Germline Mutation-Associated Ovarian Cancer.

Autor: Ngoi NYL; Natalie Y.L. Ngoi, Valerie Heong, Pei Yi Ong, Samuel G.W. Ow, Anand D. Jeyasekharan, Yi Wan Lim, Siew Eng Lim, Soo Chin Lee, and David S.P. Tan, National University Cancer Institute; Darwin Tay, Valerie Heong, Anand D. Jeyasekharan, Soo Chin Lee, and David S.P. Tan, National University of Singapore; Yee Liang Thian, Joseph Ng, Jeffrey J.H. Low, Arunachalam Ilancheran, and Sharon Z.L. Koh, National University Hospital, Singapore, Republic of Singapore., Tay D; Natalie Y.L. Ngoi, Valerie Heong, Pei Yi Ong, Samuel G.W. Ow, Anand D. Jeyasekharan, Yi Wan Lim, Siew Eng Lim, Soo Chin Lee, and David S.P. Tan, National University Cancer Institute; Darwin Tay, Valerie Heong, Anand D. Jeyasekharan, Soo Chin Lee, and David S.P. Tan, National University of Singapore; Yee Liang Thian, Joseph Ng, Jeffrey J.H. Low, Arunachalam Ilancheran, and Sharon Z.L. Koh, National University Hospital, Singapore, Republic of Singapore., Heong V; Natalie Y.L. Ngoi, Valerie Heong, Pei Yi Ong, Samuel G.W. Ow, Anand D. Jeyasekharan, Yi Wan Lim, Siew Eng Lim, Soo Chin Lee, and David S.P. Tan, National University Cancer Institute; Darwin Tay, Valerie Heong, Anand D. Jeyasekharan, Soo Chin Lee, and David S.P. Tan, National University of Singapore; Yee Liang Thian, Joseph Ng, Jeffrey J.H. Low, Arunachalam Ilancheran, and Sharon Z.L. Koh, National University Hospital, Singapore, Republic of Singapore., Thian YL; Natalie Y.L. Ngoi, Valerie Heong, Pei Yi Ong, Samuel G.W. Ow, Anand D. Jeyasekharan, Yi Wan Lim, Siew Eng Lim, Soo Chin Lee, and David S.P. Tan, National University Cancer Institute; Darwin Tay, Valerie Heong, Anand D. Jeyasekharan, Soo Chin Lee, and David S.P. Tan, National University of Singapore; Yee Liang Thian, Joseph Ng, Jeffrey J.H. Low, Arunachalam Ilancheran, and Sharon Z.L. Koh, National University Hospital, Singapore, Republic of Singapore., Ong PY; Natalie Y.L. Ngoi, Valerie Heong, Pei Yi Ong, Samuel G.W. Ow, Anand D. Jeyasekharan, Yi Wan Lim, Siew Eng Lim, Soo Chin Lee, and David S.P. Tan, National University Cancer Institute; Darwin Tay, Valerie Heong, Anand D. Jeyasekharan, Soo Chin Lee, and David S.P. Tan, National University of Singapore; Yee Liang Thian, Joseph Ng, Jeffrey J.H. Low, Arunachalam Ilancheran, and Sharon Z.L. Koh, National University Hospital, Singapore, Republic of Singapore., Ow SGW; Natalie Y.L. Ngoi, Valerie Heong, Pei Yi Ong, Samuel G.W. Ow, Anand D. Jeyasekharan, Yi Wan Lim, Siew Eng Lim, Soo Chin Lee, and David S.P. Tan, National University Cancer Institute; Darwin Tay, Valerie Heong, Anand D. Jeyasekharan, Soo Chin Lee, and David S.P. Tan, National University of Singapore; Yee Liang Thian, Joseph Ng, Jeffrey J.H. Low, Arunachalam Ilancheran, and Sharon Z.L. Koh, National University Hospital, Singapore, Republic of Singapore., Jeyasekharan AD; Natalie Y.L. Ngoi, Valerie Heong, Pei Yi Ong, Samuel G.W. Ow, Anand D. Jeyasekharan, Yi Wan Lim, Siew Eng Lim, Soo Chin Lee, and David S.P. Tan, National University Cancer Institute; Darwin Tay, Valerie Heong, Anand D. Jeyasekharan, Soo Chin Lee, and David S.P. Tan, National University of Singapore; Yee Liang Thian, Joseph Ng, Jeffrey J.H. Low, Arunachalam Ilancheran, and Sharon Z.L. Koh, National University Hospital, Singapore, Republic of Singapore., Lim YW; Natalie Y.L. Ngoi, Valerie Heong, Pei Yi Ong, Samuel G.W. Ow, Anand D. Jeyasekharan, Yi Wan Lim, Siew Eng Lim, Soo Chin Lee, and David S.P. Tan, National University Cancer Institute; Darwin Tay, Valerie Heong, Anand D. Jeyasekharan, Soo Chin Lee, and David S.P. Tan, National University of Singapore; Yee Liang Thian, Joseph Ng, Jeffrey J.H. Low, Arunachalam Ilancheran, and Sharon Z.L. Koh, National University Hospital, Singapore, Republic of Singapore., Lim SE; Natalie Y.L. Ngoi, Valerie Heong, Pei Yi Ong, Samuel G.W. Ow, Anand D. Jeyasekharan, Yi Wan Lim, Siew Eng Lim, Soo Chin Lee, and David S.P. Tan, National University Cancer Institute; Darwin Tay, Valerie Heong, Anand D. Jeyasekharan, Soo Chin Lee, and David S.P. Tan, National University of Singapore; Yee Liang Thian, Joseph Ng, Jeffrey J.H. Low, Arunachalam Ilancheran, and Sharon Z.L. Koh, National University Hospital, Singapore, Republic of Singapore., Lee SC; Natalie Y.L. Ngoi, Valerie Heong, Pei Yi Ong, Samuel G.W. Ow, Anand D. Jeyasekharan, Yi Wan Lim, Siew Eng Lim, Soo Chin Lee, and David S.P. Tan, National University Cancer Institute; Darwin Tay, Valerie Heong, Anand D. Jeyasekharan, Soo Chin Lee, and David S.P. Tan, National University of Singapore; Yee Liang Thian, Joseph Ng, Jeffrey J.H. Low, Arunachalam Ilancheran, and Sharon Z.L. Koh, National University Hospital, Singapore, Republic of Singapore., Ng J; Natalie Y.L. Ngoi, Valerie Heong, Pei Yi Ong, Samuel G.W. Ow, Anand D. Jeyasekharan, Yi Wan Lim, Siew Eng Lim, Soo Chin Lee, and David S.P. Tan, National University Cancer Institute; Darwin Tay, Valerie Heong, Anand D. Jeyasekharan, Soo Chin Lee, and David S.P. Tan, National University of Singapore; Yee Liang Thian, Joseph Ng, Jeffrey J.H. Low, Arunachalam Ilancheran, and Sharon Z.L. Koh, National University Hospital, Singapore, Republic of Singapore., Low JJH; Natalie Y.L. Ngoi, Valerie Heong, Pei Yi Ong, Samuel G.W. Ow, Anand D. Jeyasekharan, Yi Wan Lim, Siew Eng Lim, Soo Chin Lee, and David S.P. Tan, National University Cancer Institute; Darwin Tay, Valerie Heong, Anand D. Jeyasekharan, Soo Chin Lee, and David S.P. Tan, National University of Singapore; Yee Liang Thian, Joseph Ng, Jeffrey J.H. Low, Arunachalam Ilancheran, and Sharon Z.L. Koh, National University Hospital, Singapore, Republic of Singapore., Ilancheran A; Natalie Y.L. Ngoi, Valerie Heong, Pei Yi Ong, Samuel G.W. Ow, Anand D. Jeyasekharan, Yi Wan Lim, Siew Eng Lim, Soo Chin Lee, and David S.P. Tan, National University Cancer Institute; Darwin Tay, Valerie Heong, Anand D. Jeyasekharan, Soo Chin Lee, and David S.P. Tan, National University of Singapore; Yee Liang Thian, Joseph Ng, Jeffrey J.H. Low, Arunachalam Ilancheran, and Sharon Z.L. Koh, National University Hospital, Singapore, Republic of Singapore., Koh SZL; Natalie Y.L. Ngoi, Valerie Heong, Pei Yi Ong, Samuel G.W. Ow, Anand D. Jeyasekharan, Yi Wan Lim, Siew Eng Lim, Soo Chin Lee, and David S.P. Tan, National University Cancer Institute; Darwin Tay, Valerie Heong, Anand D. Jeyasekharan, Soo Chin Lee, and David S.P. Tan, National University of Singapore; Yee Liang Thian, Joseph Ng, Jeffrey J.H. Low, Arunachalam Ilancheran, and Sharon Z.L. Koh, National University Hospital, Singapore, Republic of Singapore., Tan DSP; Natalie Y.L. Ngoi, Valerie Heong, Pei Yi Ong, Samuel G.W. Ow, Anand D. Jeyasekharan, Yi Wan Lim, Siew Eng Lim, Soo Chin Lee, and David S.P. Tan, National University Cancer Institute; Darwin Tay, Valerie Heong, Anand D. Jeyasekharan, Soo Chin Lee, and David S.P. Tan, National University of Singapore; Yee Liang Thian, Joseph Ng, Jeffrey J.H. Low, Arunachalam Ilancheran, and Sharon Z.L. Koh, National University Hospital, Singapore, Republic of Singapore.

Publikováno v: JCO precision oncology [JCO Precis Oncol] 2018 Nov; Vol. 2, pp. 1-8.