Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Samuel G Schumacher"'
Autor:
Thomas H A Samuels, Romain Wyss, Stefano Ongarello, David A J Moore, Samuel G Schumacher, Claudia M Denkinger
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254002 (2021)
IntroductionA highly sensitive triage test that captures most symptomatic patients at increased likelihood of having pulmonary tuberculosis (PTB) would 'rule-out' lower-risk patients from expensive confirmatory testing. Although studies have assessed
Externí odkaz:
https://doaj.org/article/906a76910e944bc6b9e75f7db97389a5
Autor:
Sophia B Georghiou, Riccardo Alagna, Daniela M Cirillo, Sergio Carmona, Morten Ruhwald, Samuel G Schumacher
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0261442 (2021)
A laboratory validation study was conducted to assess the equivalence of Xpert MTB/RIF Ultra testing on the GeneXpert System and the GeneXpert Omni System ('Omni') for tuberculosis and rifampicin resistance. High concordance of the two devices was de
Externí odkaz:
https://doaj.org/article/9f45e76792b5478db72222e7ff06df09
Autor:
Saskia Ricks, Claudia M Denkinger, Samuel G Schumacher, Timothy B Hallett, Nimalan Arinaminpathy
Publikováno v:
PLoS Medicine, Vol 17, Iss 12, p e1003466 (2020)
BackgroundLateral flow urine lipoarabinomannan (LAM) tests could offer important new opportunities for the early detection of tuberculosis (TB). The currently licensed LAM test, Alere Determine TB LAM Ag ('LF-LAM'), performs best in the sickest peopl
Externí odkaz:
https://doaj.org/article/521f1d258c1e48b09986a43495747fb1
Autor:
Tobias Broger, Mark P Nicol, Rita Székely, Stephanie Bjerrum, Bianca Sossen, Charlotte Schutz, Japheth A Opintan, Isik S Johansen, Satoshi Mitarai, Kinuyo Chikamatsu, Andrew D Kerkhoff, Aurélien Macé, Stefano Ongarello, Graeme Meintjes, Claudia M Denkinger, Samuel G Schumacher
Publikováno v:
PLoS Medicine, Vol 17, Iss 5, p e1003113 (2020)
BackgroundTuberculosis (TB) is the most common cause of death in people living with HIV (PLHIV), yet TB often goes undiagnosed since many patients are not able to produce a sputum specimen, and traditional diagnostics are costly or unavailable. A nov
Externí odkaz:
https://doaj.org/article/9a4bb3474d674111a7af649e6ee3100f
Publikováno v:
PLoS Medicine, Vol 14, Iss 12, p e1002472 (2017)
BackgroundThe Xpert MTB/RIF (Xpert) assay offers rapid and accurate diagnosis of tuberculosis (TB) but still suffers from imperfect sensitivity. The newer Xpert MTB/RIF Ultra cartridge has shown improved sensitivity in recent field trials, but at the
Externí odkaz:
https://doaj.org/article/70cb12257113444e99b477d176888196
Autor:
Joshua Havumaki, Doris Hillemann, Nazir Ismail, Shaheed Vally Omar, Sophia B Georghiou, Samuel G Schumacher, Catharina Boehme, Claudia M Denkinger
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173804 (2017)
INTRODUCTION:Despite recent diagnostic advances, the majority of multidrug-resistant tuberculosis (MDR-TB) cases remain undiagnosed. Line probes assays (LiPAs) hold great promise to curb the spread of MDR-TB as they can rapidly detect MDR-TB even whe
Externí odkaz:
https://doaj.org/article/e0f7104a9c424a29ac5e07a9f760d0d0
Autor:
Samuel G Schumacher, Hojoon Sohn, Zhi Zhen Qin, Genevieve Gore, J Lucian Davis, Claudia M Denkinger, Madhukar Pai
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151073 (2016)
BACKGROUND:Several reviews on the accuracy of Tuberculosis (TB) Nucleic Acid Amplification Tests (NAATs) have been performed but the evidence on their impact on patient-important outcomes has not been systematically reviewed. Given the recent increas
Externí odkaz:
https://doaj.org/article/83a568425130433080a3b461e555af24
Autor:
Claudia M Denkinger, Yatiraj Kalantri, Samuel G Schumacher, Joy S Michael, Deepa Shankar, Arvind Saxena, Natarajan Sriram, Thangakunam Balamugesh, Robert Luo, Nira R Pollock, Madhukar Pai, Devasahayam J Christopher
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e85447 (2013)
Existing diagnostic tests for pleural tuberculosis (TB) have inadequate accuracy and/or turnaround time. Interferon-gamma (IFNg) has been identified in many studies as a biomarker for pleural TB. Our objective was to develop a lateral flow, immunochr
Externí odkaz:
https://doaj.org/article/76e79e1cb9794335aafea9c687182e4f
Autor:
Ioana D. Olaru, Mina Beliz Meier, Fuad Mirzayev, Nevena Prodanovic, Philip J. Kitchen, Samuel G. Schumacher, Claudia M. Denkinger
Publikováno v:
eClinicalMedicine
BACKGROUND: There is a substantial overlap in the epidemiology of chronic hepatitis B (HBV), hepatitis C (HCV) and tuberculosis (TB) due to overlapping risk factors. Testing for viral hepatitis is not widely recommended for patients with TB. The aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362ded0aa0b5d060fe8039566c5bb8c6
https://europepmc.org/articles/PMC10113747/
https://europepmc.org/articles/PMC10113747/
Autor:
Anura David, Francesca Conradie, Nelly Ciobanu, Claudia M. Denkinger, Lesley Scott, Adam Penn-Nicholson, Valeriu Crudu, Samuel G Schumacher, Vithal Prasad Myneedu, Sophia B. Georghiou, Camilla Rodrigues, Mubin Kazi, Manpreet Bhalla, Morten Ruhwald
Publikováno v:
The Lancet Infectious Diseases. 22:242-249
Summary Background The WHO End TB Strategy requires drug susceptibility testing and treatment of all people with tuberculosis, but second-line diagnostic testing with line-probe assays needs to be done in experienced laboratories with advanced infras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42072c0a7cfa857dc15d51c5210b6a23
https://doi.org/10.1016/s1473-3099(21)00452-7
https://doi.org/10.1016/s1473-3099(21)00452-7