Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Samuel Flashner"'
Autor:
Bartosz Mucha, Shuo Qie, Sagar Bajpai, Vincenzo Tarallo, J. Nathaniel Diehl, Frank Tedeschi, Gao Zhou, Zhaofeng Gao, Samuel Flashner, Andres J. Klein-Szanto, Hanina Hibshoosh, Shimonosono Masataka, Olga S. Chajewski, Ireneusz Majsterek, Dariusz Pytel, Maria Hatzoglou, Channing J. Der, Hiroshi Nakagawa, Adam J. Bass, Kwok-Kin Wong, Serge Y. Fuchs, Anil K. Rustgi, Eckhard Jankowsky, J. Alan Diehl
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Cytoplasmic accumulation of RNA binding protein, hnRNPK in cancer cells is associated with poor prognosis. Here the authors show that SCFFbxo4 E3 ubiquitin ligase-mediated polyubiquitylation of hnRNPK restricts c-Myc translation and limits cancer pro
Externí odkaz:
https://doaj.org/article/fecd2f81e26b43a3b3aad7932728969f
Autor:
Ogoegbunam Okolo, Emily Honzel, William R. Britton, Victoria X. Yu, Samuel Flashner, Cecilia Martin, Hiroshi Nakagawa, Anuraag S. Parikh
Publikováno v:
Cancers, Vol 15, Iss 24, p 5810 (2023)
The microscopic species colonizing the human body, collectively referred to as the microbiome, play a crucial role in the maintenance of tissue homeostasis, immunity, and the development of disease. There is evidence to suggest associations between a
Externí odkaz:
https://doaj.org/article/72f4dad6692d40cfaf0eba505b9bc504
Autor:
Ogoegbunam Okolo, Victoria Yu, Samuel Flashner, Cecilia Martin, Hiroshi Nakagawa, Derrick T. Lin, Sidharth V. Puram, Anuraag S. Parikh
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102294- (2023)
Summary: Tumors originating from the head and neck represent diverse histologies and are comprised of several cell types, including malignant cells, cancer-associated fibroblasts, endothelial cells, and immune cells. In this protocol, we describe a s
Externí odkaz:
https://doaj.org/article/b4f99ac00e4c4b30acec4443fc2f2cc7
Autor:
Masataka Shimonosono, Koji Tanaka, Samuel Flashner, Satoshi Takada, Norihiro Matsuura, Yasuto Tomita, Uma M. Sachdeva, Eishi Noguchi, Veena Sangwan, Lorenzo Ferri, Fatemeh Momen-Heravi, Angela J. Yoon, Andres J. Klein-Szanto, J. Alan Diehl, Hiroshi Nakagawa
Publikováno v:
Biomolecules, Vol 11, Iss 10, p 1479 (2021)
Background: Alcohol (ethanol) consumption is a major risk factor for head and neck and esophageal squamous cell carcinomas (SCCs). However, how ethanol (EtOH) affects SCC homeostasis is incompletely understood. Methods: We utilized three-dimensional
Externí odkaz:
https://doaj.org/article/fe42990241114821856eceaf0fc458e5
Publikováno v:
Microorganisms, Vol 9, Iss 11, p 2182 (2021)
The microbiome is an emerging key co-factor in the development of esophageal cancer, the sixth leading cause of cancer death worldwide. However, there is a paucity of data delineating how the microbiome contributes to the pathobiology of the two hist
Externí odkaz:
https://doaj.org/article/4d54caed2a3a4029b7bd59d588f1884c
Publikováno v:
Chromosoma. 131:175-191
Aneuploidy is a pervasive feature of cancer cells that results from chromosome missegregation. Several transcription factors have been associated with aneuploidy; however, no studies to date have demonstrated that mammalian transcription factors dire
Autor:
Samuel Flashner, Masataka Shimonosono, Norihiro Matsuura, Shinya Ohashi, Andres J. Klein-Szanto, J. Alan Diehl, Che-Hong Chen, Daria Mochly-Rosen, Hiroshi Nakagawa
The alcohol metabolite acetaldehyde is a potent human carcinogen. Aldehyde dehydrogenase 2 (ALDH2) is the primary enzyme that detoxifies acetaldehyde in the mitochondria. Acetaldehyde accumulates and causes genotoxic stress in cells expressing the dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84ad695e0f6cee8a6a618115f7082b25
https://doi.org/10.1101/2023.04.03.534985
https://doi.org/10.1101/2023.04.03.534985
Autor:
Anuraag S. Parikh, Victoria X. Yu, Samuel Flashner, Ogoegbunam B. Okolo, Chao Lu, Brian S. Henick, Fatemeh Momen-Heravi, Sidharth V. Puram, Theodoros Teknos, Quintin Pan, Hiroshi Nakagawa
Publikováno v:
Oral Oncology. 138:106330
Autor:
Benjamin Wright, Mia Masuda, Samuel Flashner, Jessica Gibson, Huijun Luo, Arina Putikova, Grace Pyon, Matthew Rank, Hiroshi Nakagawa, Hirohito Kita, Emily Cope, Alfred Doyle
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:AB89
Publikováno v:
Microorganisms, Vol 9, Iss 2182, p 2182 (2021)
Microorganisms
Microorganisms
The microbiome is an emerging key co-factor in the development of esophageal cancer, the sixth leading cause of cancer death worldwide. However, there is a paucity of data delineating how the microbiome contributes to the pathobiology of the two hist