Výsledky vyhledávání - "Samuel Eaton"

Akademický článek

Case of Samuel Eaton and others for keeping a conventicle.

Publikováno v: Camden New Series; Jan1886, Vol. 39 Issue 1, p284-286, 3p

A Single Intravenous rAAV Injection as Late as P20 Achieves Efficacious and Sustained CNS Gene Therapy in Canavan Mice

Autor: Daniel A. Kirschner, Constance M. Moore, Thomas N. Seyfried, Elif M. Sikoglu, Huapeng Li, Reuben Matalon, Jun Xie, Sylvia Szucs, Terence R. Flotte, Ana A. Liso Navarro, Andrew R. Denninger, Guangping Gao, Hongwei Zhang, Samuel Eaton, Seemin Seher Ahmed, Chunyan Cao, Qin Su

Publikováno v: Molecular Therapy. 21:2136-2147

Canavan's disease (CD) is a fatal pediatric leukodystrophy caused by mutations in aspartoacylase (AspA) gene. Currently, there is no effective treatment for CD; however, gene therapy is an attractive approach to ameliorate the disease. Here, we studi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909841e3b2242fd785a839a676201b74
https://doi.org/10.1038/mt.2013.138

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AAV-Mediated Gene Delivery in a Feline Model of Sandhoff Disease Corrects Lysosomal Storage in the Central Nervous System

Autor: Aime K. Johnson, Hannah E. Rockwell, Ashley N. Randle, Miguel Sena-Esteves, Judith A. Hudson, Douglas R. Martin, Heather L. Gray-Edwards, Victoria J. McCurdy, Allison M. Bradbury, Samuel Eaton, Henry J. Baker, Nancy R. Cox, Diane U. Wilson, Thomas N. Seyfried

Publikováno v: ASN NEURO
ASN Neuro, Vol 7 (2015)

Sandhoff disease (SD) is an autosomal recessive neurodegenerative disease caused by a mutation in the gene for the β-subunit of β-N-acetylhexosaminidase (Hex), resulting in the inability to catabolize ganglioside GM2 within the lysosomes. SD presen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00cada2388a7fa1d37bd90a5ed34804e
http://europepmc.org/articles/PMC4720176

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GM1-gangliosidosis in American black bears: clinical, pathological, biochemical and molecular genetic characterization

Publikováno v: Molecular genetics and metabolism. 111(4)

G(M1)-gangliosidosis is a rare progressive neurodegenerative disorder due to an autosomal recessively inherited deficiency of lysosomal β-galactosidase. We have identified seven American black bears (Ursus americanus) found in the Northeast United S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184c07cb2816f02edef8f7e7a8e3a369
https://pubmed.ncbi.nlm.nih.gov/24581871

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