Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Samuel E DePrimo"'
Autor:
Koen Dudink, Klasiena Bouwman, Yanqing Chen, Samuel E DePrimo, Ernesto J Munoz-Elias, Pim Aarts, Renske Schappin, Edwin F Florencia, Bennie van Heeswijk, Lisette M Prens, Hessel H van der Zee, Errol P Prens, Kelsey R van Straalen, Barbara Horváth
Publikováno v:
The British journal of dermatology, 188(5), 601-609. Wiley-Blackwell Publishing Ltd
Background The effectiveness of available biologics for the treatment of hidradenitis suppurativa (HS) is limited. Additional therapeutic options are needed. Objectives To investigate the efficacy and mode of action of guselkumab [an anti-interleukin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4457f6eced82e3dbd65f4c82173954
https://pure.eur.nl/en/publications/b84d9b3c-e402-4832-8c4a-fdc9e1f2d91c
https://pure.eur.nl/en/publications/b84d9b3c-e402-4832-8c4a-fdc9e1f2d91c
Autor:
George D. Demetri, Charles M. Baum, Jaap Verweij, Manisha H. Shah, Patrick Schöffski, Charles S. Harmon, Christopher R. Garrett, Martin E. Blackstein, Xin Huang, Samuel E. DePrimo
CCR Translation for the Article from Circulating Levels of Soluble KIT Serve as a Biomarker for Clinical Outcome in Gastrointestinal Stromal Tumor Patients Receiving Sunitinib following Imatinib Failure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54af5ae49f102288689e6466f65b5c7
https://doi.org/10.1158/1078-0432.22439949
https://doi.org/10.1158/1078-0432.22439949
Autor:
George D. Demetri, Charles M. Baum, Jaap Verweij, Manisha H. Shah, Patrick Schöffski, Charles S. Harmon, Christopher R. Garrett, Martin E. Blackstein, Xin Huang, Samuel E. DePrimo
Supplementary Data from Circulating Levels of Soluble KIT Serve as a Biomarker for Clinical Outcome in Gastrointestinal Stromal Tumor Patients Receiving Sunitinib following Imatinib Failure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd92c17319307a3ae29839274fa37af
https://doi.org/10.1158/1078-0432.22439946
https://doi.org/10.1158/1078-0432.22439946
Autor:
George D. Demetri, Charles M. Baum, Jaap Verweij, Manisha H. Shah, Patrick Schöffski, Charles S. Harmon, Christopher R. Garrett, Martin E. Blackstein, Xin Huang, Samuel E. DePrimo
Purpose: To evaluate changes in circulating levels of soluble KIT (sKIT) extracellular domain as a potential biomarker for clinical outcome in gastrointestinal stromal tumor patients treated with the multitargeted tyrosine kinase inhibitor sunitinib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5525abe0dad4bff99334c9aea8447c95
https://doi.org/10.1158/1078-0432.c.6517329
https://doi.org/10.1158/1078-0432.c.6517329
Autor:
Weiyang Tao, Juliëtte N Pouw, Julia Drylewicz, Samuel E. DePrimo, Ernesto J. Muñoz-Elías, Marianne Boes, Tessa S. van Kempen, Deepak M.W. Balak, Timothy R D J Radstake, Aridaman Pandit, Emmerik F A Leijten, Janneke Tekstra, Michel Olde Nordkamp
Publikováno v:
Rheumatology (Oxford, England)
Objective To identify novel serum proteins involved in the pathogenesis of PsA as compared with healthy controls, psoriasis (Pso) and AS, and to explore which proteins best correlated to major clinical features of the disease. Methods A high-throughp
Autor:
Gary S. Firestein, David L. Boyle, Dion Chen, Cesar Calderon, Samuel E. DePrimo, Paul J. Dunford, Robin L. Thurmond, William Barchuk
Publikováno v:
Inflammation Research. 68:261-274
In a double-blind, placebo-controlled, multiple-dose study, we assessed the molecular mechanism of action of the selective histamine-4-receptor antagonist toreforant. Patients with active rheumatoid arthritis (RA) despite methotrexate were randomized
Autor:
Michael A. Loesche, Kamyar Farahi, Elizabeth A. Grice, Amanda S. Tyldsley, Samuel E. DePrimo, Marc Chevrier, Carrie Brodmerkel, Joseph Horwinski, Kristina Callis Duffin, Steven Fakharzadeh, Kimberly A. Capone, Kevin D. Smith, Andrew Blauvelt, Ernesto J. Muñoz-Elías, Bidisha Dasgupta
Publikováno v:
Journal of Investigative Dermatology. 138:1973-1981
Plaque psoriasis, a chronic inflammatory disease primarily affecting the skin, is thought to have a multifactorial etiology, including innate immune system dysregulation, environmental triggers, and genetic susceptibility. We sought to further unders
Autor:
David L, Boyle, Samuel E, DePrimo, Cesar, Calderon, Dion, Chen, Paul J, Dunford, William, Barchuk, Gary S, Firestein, Robin L, Thurmond
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 68(4)
In a double-blind, placebo-controlled, multiple-dose study, we assessed the molecular mechanism of action of the selective histamine-4-receptor antagonist toreforant.Patients with active rheumatoid arthritis (RA) despite methotrexate were randomized
Autor:
Mehrdad Khajavi, John V. Heymach, Samuel E. DePrimo, William Carley, Matthew H. Kulke, Heinz-Josef Lenz, Xin-Yun Huang, E. Lin, Hua-Kang Wu, Amado J. Zurita, Charles S. Harmon, Neal J. Meropol, X. Wang, L. Tye
Publikováno v:
British Journal of Cancer
Background: Sunitinib is approved worldwide for treatment of advanced pancreatic neuroendocrine tumours (pNET), but no validated markers exist to predict response. This analysis explored biomarkers associated with sunitinib activity and clinical bene
Autor:
George D. Demetri, Charles S. Harmon, Christopher R. Garrett, Xin Huang, Martin E. Blackstein, Charles M. Baum, Patrick Schöffski, Jaap Verweij, Samuel E. DePrimo, Manisha H. Shah
Publikováno v:
Clinical Cancer Research. 15:5869-5877
Purpose: To evaluate changes in circulating levels of soluble KIT (sKIT) extracellular domain as a potential biomarker for clinical outcome in gastrointestinal stromal tumor patients treated with the multitargeted tyrosine kinase inhibitor sunitinib