Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Samuel Drinkall"'
Autor:
Samuel Drinkall, Catherine B. Lawrence, Bernadino Ossola, Samuel Russell, Clare Bender, Nicola B. Brice, Lee A. Dawson, Michael Harte, David Brough
Publikováno v:
Glia. 70:1301-1316
The NLRP3 (NLR family, pyrin domain containing 3) inflammasome is a multi-protein complex responsible for the activation of caspase-1 and the subsequent cleavage and activation of the potent proinflammatory cytokines IL-1β and IL-18, and pyroptotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd23d64a1806c65a4cb1a3005dd0914
https://doi.org/10.1002/glia.24174
https://doi.org/10.1002/glia.24174
Autor:
Bernardino Ossola, Ali Rifat, Anna Rowland, Helen Hunter, Samuel Drinkall, Clare Bender, Mayida Hamlischer, Martin Teall, Russell Burley, Daneil F. Barker, David Cadwalladr, Louise Dickson, Jason M.K. Lawrence, Jenna R.M. Harvey, Marina Lizio, Xiao Xu, Edel Kavanagh, Toni Cheung, Steve Sheardown, Catherine B. Lawrence, Michael Harte, David Brough, Christian Madry, Kim Matthews, Kevin Doyle, Keith Page, Justin Powell, Nicola L. Brice, Roland W. Bürli, Mark B. Carlton, Lee A. Dawson
Publikováno v:
Neuropharmacology. 224
Neuroinflammation, specifically the NLRP3 inflammasome cascade, is a common underlying pathological feature of many neurodegenerative diseases. Evidence suggests that NLRP3 activation involves changes in intracellular K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28dc2da491de466f3d474771aad12f3b
https://pubmed.ncbi.nlm.nih.gov/36375694
https://pubmed.ncbi.nlm.nih.gov/36375694
Autor:
Alison E. Mather, Jack Rivers-Auty, Harry G. Spence, Christopher Hoyle, Michael J.D. Daniels, Shi Yu, Margaret Jane Gordon, James Cook, David Brough, Paul T. Kennedy, John H. Beattie, Amy Bradley, Victor S. Tapia, Ruth Peters, Samuel Drinkall, Te-Chen Tzeng, Claire S. White, Catherine B. Lawrence, Jack Peter Green
Publikováno v:
The Journal of Neuroscience
Alzheimer's disease is a devastating neurodegenerative disease with a dramatically increasing prevalence and no disease-modifying treatment. Inflammatory lifestyle factors increase the risk of developing Alzheimer's disease. Zinc deficiency is the mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7018a3cbf7c3fb7a28bf046d53d9335
http://europepmc.org/articles/PMC8018890
http://europepmc.org/articles/PMC8018890