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pro vyhledávání: '"Samuel D. Yeh"'
Phase I Study of Targeted Radioimmunotherapy for Leptomeningeal Cancers Using Intra-Ommaya 131-I-3F8
Autor:
Pat Zanzonico, Samuel D. Yeh, John L. Humm, Kim Kramer, William L. Gerald, Yasmin Khakoo, Steven M. Larson, Henry W. Yeung, Mark M. Souweidane, Ronald D. Finn, Ira J. Dunkel, Nai-Kong V. Cheung, Suzanne L. Wolden
Publikováno v:
Journal of Clinical Oncology. 25:5465-5470
Purpose Tumors metastasizing to the CNS and leptomeninges (LM) are associated with significant mortality. We tested the toxicity, pharmacokinetics, and dosimetry of intraventricular iodine-131–labeled monoclonal antibody 3F8 (131I-3F8) targeting GD