Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Samuel D. Foster"'
Autor:
Mark A. Dawson, Samuel D. Foster, Andrew J. Bannister, Samuel C. Robson, Rebecca Hannah, Xiaonan Wang, Blerta Xhemalce, Andrew D. Wood, Anthony R. Green, Berthold Göttgens, Tony Kouzarides
Publikováno v:
Cell Reports, Vol 2, Iss 3, Pp 470-477 (2012)
The JAK2 tyrosine kinase is a critical mediator of cytokine-induced signaling. It plays a role in the nucleus, where it regulates transcription by phosphorylating histone H3 at tyrosine 41 (H3Y41ph). We used chromatin immunoprecipitation coupled to m
Externí odkaz:
https://doaj.org/article/ab41808cb7824feba4f92a5c2bea78b2
Autor:
Mukesh Dhariwal, Ray Griner, Philippe Charles Crozafon, Christine Bouchet, Samuel D Foster, Monia Zignani, Ming Zou
Publikováno v:
European Journal of Ophthalmology. 31:1809-1816
Purpose: This study compared real-world safety and efficacy outcomes of cataract surgery performed with LenSx femtosecond laser-assisted cataract surgery or manual phacoemulsification cataract surgery procedures. Methods: A retrospective observationa
Autor:
John E. Pimanda, Samuel D. Foster, Marella F. T. R. de Bruijn, Judith Schütte, Polynikis Kaimakis, Berthold Göttgens, Kathy Knezevic, Nicola K. Wilson, Xiaonan Wang, Sarah Kinston, Paulina M. Chilarska, Elaine Dzierzak, Willem H. Ouwehand
Publikováno v:
Cell Stem Cell. 7(4):532-544
SUMMARY Combinatorial transcription factor (TF) interactions control cellular phenotypes and, therefore, underpin stem cell formation, maintenance, and differentiation. Here, we report the genome-wide binding patterns and combinatorial interactions f
Autor:
Berthold Göttgens, Till Bartke, Andrew J. Bannister, Anthony R. Green, Samuel D. Foster, Mark A. Dawson, Tony Kouzarides
Publikováno v:
Nature. 461:819-822
Activation of Janus kinase 2 (JAK2) by chromosomal translocations or point mutations is a frequent event in haematological malignancies. JAK2 is a non-receptor tyrosine kinase that regulates several cellular processes by inducing cytoplasmic signalli
Autor:
Mark A. Dawson, Fernando J Calero-Nieto, Diego Miranda-Saavedra, Xiao Hong Sun, Sarah A. Teichmann, Nicolas Bonadies, Samuel D. Foster, Stephanie Dumon, Nicola K. Wilson, Andrew J. Bannister, Ian J. Donaldson, Jonathan Frampton, Berthold Göttgens, Rekin's Janky, Sarah Kinston
Publikováno v:
Blood. 113:5456-5465
The basic helix-loop-helix transcription factor Scl/Tal1 controls the development and subsequent differentiation of hematopoietic stem cells (HSCs). However, because few Scl target genes have been validated to date, the underlying mechanisms have rem
Autor:
Xiaonan Wang, Rebecca Hannah, Andrew D. Wood, Berthold Göttgens, Tony Kouzarides, Mark A. Dawson, Blerta Xhemalce, Anthony R. Green, Andrew J. Bannister, Samuel Robson, Samuel D. Foster
Publikováno v:
Cell Reports
Cell Reports, Vol 2, Iss 3, Pp 470-477 (2012)
Cell Reports, Vol 2, Iss 3, Pp 470-477 (2012)
Summary The JAK2 tyrosine kinase is a critical mediator of cytokine-induced signaling. It plays a role in the nucleus, where it regulates transcription by phosphorylating histone H3 at tyrosine 41 (H3Y41ph). We used chromatin immunoprecipitation coup
Autor:
Brynn T. Kvinlaug, Samuel D. Foster, Anthony D. Whetton, Elaine Spooncer, Nicolas Bonadies, Brian J. P. Huntly, Dominik Spensberger, Andrew J. Bannister, Berthold Göttgens, Wai In Chan, Mark A. Dawson
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16330 (2011)
PLoS ONE
PLoS ONE
Acute leukaemias are commonly caused by mutations that corrupt the transcriptional circuitry of haematopoietic stem/progenitor cells. However, the mechanisms underlying large-scale transcriptional reprogramming remain largely unknown. Here we investi
Publikováno v:
Molecular BioSystems. 5:1413
Haematopoiesis (or blood formation) in general and haematopoietic stem cells more specifically represent some of the best studied mammalian developmental systems. Sophisticated purification protocols coupled with powerful biological assays permit fun
Publikováno v:
Developmental Cell
Summary We have developed a method for rapidly inactivating proteins with rapamycin-induced heterodimerization. Cells were stably transfected with siRNA-resistant, FKBP-tagged subunits of the adaptor protein (AP) complexes of clathrin-coated vesicles