Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Samuel D Paskin-Flerlage"'
Autor:
Kathryn R Coser, Ivana Nikolic, Xiuli Huang, Anthony J Faugno, Samuel D Paskin-Flerlage, Stephen P. Berasi, Kari E. Roberts, Geoffrey A. Bocobo, Paul D. Upton, Lai Ming Yung, Rajeev Malhotra, Teresa Dinter, Raymond T. Chung, Kathleen E. Tumelty, Megan E. McNeil, Nicholas W. Morrell, Arthur Lee, Carol S. Lai, Marie-José Goumans, Wei Zheng, Luca Troncone, Christine Huard, Peiran Yang, C. Gregory Elliott, Richard W Channick, Paul B. Yu, Roham T. Zamanian
Publikováno v:
American Journal of Respiratory and Critical Care Medicine, 199(7), 891-902. AMER THORACIC SOC
American Journal of Respiratory and Critical Care Medicine
American Journal of Respiratory and Critical Care Medicine
RATIONALE: BMP9 (bone morphogenetic protein 9) is a circulating endothelial quiescence factor with protective effects in pulmonary arterial hypertension (PAH). Loss-of-function mutations in BMP9, its receptors, and downstream effectors have been repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64dbe9c17a8e976df4f924f8d01c0dc
http://hdl.handle.net/1887/122297
http://hdl.handle.net/1887/122297
Autor:
Paul B. Yu, Ivana Nikolic, Lai Ming Yung, R. Scott Pearsall, Samuel D Paskin-Flerlage, Ravindra Kumar
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 194:1140-1151
Transforming growth factor-β (TGF-β) ligands signal via type I and type II serine-threonine kinase receptors to regulate broad transcriptional programs. Excessive TGF-β-mediated signaling is implicated in the pathogenesis of pulmonary arterial hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd2e8791ded5a1b8cf4c36a54ba7f5bd
https://doi.org/10.1164/rccm.201510-1955oc
https://doi.org/10.1164/rccm.201510-1955oc
Autor:
Donna Y. Deng, Roham T. Zamanian, Samuel D Paskin-Flerlage, Robert Spencer, Jonathan W. Schmidt, Richard N. Channick, Patrick Zimmerman, Nicholas W. Morrell, C. Gregory Elliott, William Parker, Mark Southwood, Paul B. Yu, Carol S. Lai, Rajeev Malhotra
Publikováno v:
Pulmonary Circulation
The diagnosis of pulmonary arterial hypertension (PAH) is frequently delayed. We hypothesized that circulating angiogenic modulatory protein levels might correspond with vascular remodeling activity and serve as sensitive biomarkers of PAH. Levels of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4875dbc02753a802d006167e8156e340
https://doi.org/10.4103/2045-8932.110445
https://doi.org/10.4103/2045-8932.110445
Autor:
Lai Ming Yung, Ravindra Kumar, Ivana Nikolic, Samuel D Paskin-Flerlage, Scott Pearsall, Paul B. Yu
Publikováno v:
Circulation. 130
Introduction: Excessive Transforming Growth Factor-β (TGF-β) signaling has been implicated in pulmonary arterial hypertension (PAH), based on activation of TGF-β effectors and transcriptional targets in affected lungs and the ability of TGF-β typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7af54218b723458a9a87376865559bb
https://doi.org/10.1161/circ.130.suppl_2.17285
https://doi.org/10.1161/circ.130.suppl_2.17285
Autor:
Kari E. Roberts, Rajeev Malhotra, Samuel D Paskin-Flerlage, Richard N. Channick, Raymond T. Chung, Lai Ming Yung, Ivana Nikolic, Paul B. Yu
Publikováno v:
Circulation. 130
Background: Dysregulated bone morphogenetic protein (BMP) signaling is thought to contribute to the pathogenesis of pulmonary arterial hypertension (PAH). BMP9 can be detected in the circulation at physiologically active concentrations, and is though
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9affbd62d3353189b49640206a2d5547
https://doi.org/10.1161/circ.130.suppl_2.20267
https://doi.org/10.1161/circ.130.suppl_2.20267