The Challenges and Lessons Learned Building a New UK Infrastructure for Finding and Accessing Population-Wide COVID-19 Data for Research and Public Health Analysis: The CO-CONNECT Project

Autor: Emily Jefferson, Gordon Milligan, Jenny Johnston, Shahzad Mumtaz, Christian Cole, Joseph Best, Thomas Charles Giles, Samuel Cox, Erum Masood, Scott Horban, Esmond Urwin, Jillian Beggs, Antony Chuter, Gerry Reilly, Andrew Morris, David Seymour, Susan Hopkins, Aziz Sheikh, Philip Quinlan

Publikováno v: Journal of Medical Internet Research, Vol 26, p e50235 (2024)

The COVID-19-Curated and Open Analysis and Research Platform (CO-CONNECT) project worked with 22 organizations across the United Kingdom to build a federated platform, enabling researchers to instantaneously and dynamically query federated datasets t

Externí odkaz: https://doaj.org/article/c87a9429b5954462975595ce83bbfdf5

A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study

Autor: Emily Jefferson, Christian Cole, Shahzad Mumtaz, Samuel Cox, Thomas Charles Giles, Sam Adejumo, Esmond Urwin, Daniel Lea, Calum Macdonald, Joseph Best, Erum Masood, Gordon Milligan, Jenny Johnston, Scott Horban, Ipek Birced, Christopher Hall, Aaron S Jackson, Clare Collins, Sam Rising, Charlotte Dodsley, Jill Hampton, Andrew Hadfield, Roberto Santos, Simon Tarr, Vasiliki Panagi, Joseph Lavagna, Tracy Jackson, Antony Chuter, Jillian Beggs, Magdalena Martinez-Queipo, Helen Ward, Julie von Ziegenweidt, Frances Burns, Joanne Martin, Neil Sebire, Carole Morris, Declan Bradley, Rob Baxter, Anni Ahonen-Bishopp, Paul Smith, Amelia Shoemark, Ana M Valdes, Benjamin Ollivere, Charlotte Manisty, David Eyre, Stephanie Gallant, George Joy, Andrew McAuley, David Connell, Kate Northstone, Katie Jeffery, Emanuele Di Angelantonio, Amy McMahon, Mat Walker, Malcolm Gracie Semple, Jessica Mai Sims, Emma Lawrence, Bethan Davies, John Kenneth Baillie, Ming Tang, Gary Leeming, Linda Power, Thomas Breeze, Duncan Murray, Chris Orton, Iain Pierce, Ian Hall, Shamez Ladhani, Natalie Gillson, Matthew Whitaker, Laura Shallcross, David Seymour, Susheel Varma, Gerry Reilly, Andrew Morris, Susan Hopkins, Aziz Sheikh, Philip Quinlan

Publikováno v: Journal of Medical Internet Research, Vol 24, Iss 12, p e40035 (2022)

BackgroundCOVID-19 data have been generated across the United Kingdom as a by-product of clinical care and public health provision, as well as numerous bespoke and repurposed research endeavors. Analysis of these data has underpinned the United Kingd

Externí odkaz: https://doaj.org/article/54ca7e259fa5437b93518def8143ad8f

eP443: Fetal fraction amplification within NIPS enables detection of clinically-relevant genome-wide copy-number variants to 1Mb resolution

Autor: Ashley Acevedo, Samuel Cox, Heather Labreche, Maria Alfaro, Summer Pierson, Susan Hancock, Krista Moyer, Jo Yeleswarapu, Sun Hong, Kevin Haas, Dale Muzzey

Publikováno v: Genetics in Medicine. 24:S278

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6751b7b67e9a03f8d1d450ac8b0cc09f
https://doi.org/10.1016/j.gim.2022.01.476

Contribution of large genomic deletions to recessive Mendelian disease carrier burden within a healthy population

Autor: Samuel Cox, Raul Torres, Erik Zmuda, John Castiblanco

Publikováno v: Molecular Genetics and Metabolism. 132:S305

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aa67bf7fcb920d60e391de141493dbd0
https://doi.org/10.1016/s1096-7192(21)00553-9

Environmental Assessment for Installation of a New Jet Engine Test Cell, Edwards Air Force Base, California

Autor: Samuel Cox

The Proposed Action involves the installation of a new 35,000 square feet JETC facility with 15,000 square feet storage barn at Edwards AFB. The new facility would be located on the Main Base near the existing maintenance facility (Building 3810). Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a808358f59c5785c7fb8a5136b4e52f2
https://doi.org/10.21236/ada570509