Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Samuel Calderwood"'
Publikováno v:
Value in Health. 23:S704
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb0ff51d747f42ddc365ad8de7c6fb3e
https://doi.org/10.1016/j.jval.2020.08.1820
https://doi.org/10.1016/j.jval.2020.08.1820
Autor:
Stefan Verhoog, Katherine Wheelhouse, Matthew Tredwell, Véronique Gouverneur, Lukas Pfeifer, Tanatorn Khotavivattana, Samuel Calderwood, Thomas Lee Collier
Publikováno v:
Synlett. 27:25-28
We report the synthesis of [18F]arylCF3 and [18F]arylCHF2 derivatives from arylCF2Br and arylCHFCl precursors applying a silver-mediated halogen exchange with [18F]fluoride. In the absence of Ag(I)OTf, no reaction takes place at room temperature for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2b09c25c8108f3f925abff518dfb326
https://doi.org/10.1055/s-0035-1560592
https://doi.org/10.1055/s-0035-1560592
Autor:
Véronique Gouverneur, Matthew Tredwell, Samuel Calderwood, Katherine M. P. Wheelhouse, Tanatorn Khotavivattana, Stefan Verhoog, Thomas Lee Collier, Lukas Pfeifer
Publikováno v:
Angewandte Chemie. 127:10129-10133
We report that halogenophilic silver(I) triflate permits halogen exchange (halex) nucleophilic 18F‐fluorination of aryl‐OCHFCl, ‐OCF2Br and ‐SCF2Br precursors under mild conditions. This AgI‐mediated process allows for the first time access
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d88e04b90dcfd79ef3ebb88bff4fc8e3
https://doi.org/10.1002/ange.201504665
https://doi.org/10.1002/ange.201504665
Autor:
Katherine Wheelhouse, Véronique Gouverneur, Matthew Tredwell, Samuel Calderwood, Lukas Pfeifer, Thomas Lee Collier, Stefan Verhoog, Tanatorn Khotavivattana
Publikováno v:
Angewandte Chemie International Edition. 54:9991-9995
We report that halogenophilic silver(I) triflate permits halogen exchange (halex) nucleophilic (18)F-fluorination of aryl-OCHFCl, -OCF2Br and -SCF2Br precursors under mild conditions. This Ag(I)-mediated process allows for the first time access to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d019e6485ffadfdb3a9027f844738caf
https://doi.org/10.1002/anie.201504665
https://doi.org/10.1002/anie.201504665
Autor:
Samuel Calderwood, Thomas Lee Collier, Véronique Gouverneur, Stefan Verhoog, Lukas Pfeifer, Neil Vasdev, Sean Preshlock, Tanatorn Khotavivattana
In this work, we describe the (18)F-labeling of α,α-difluoro-α-(aryloxy)acetic acid derivatives and demonstrate that these building blocks are amenable to post-(18)F-fluorination functionalization. Protodecarboxylation offers a new entry to (18)F-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698b3c3317fa65b64df8c840dba67b0b
https://ora.ox.ac.uk/objects/uuid:8836bf2a-5f5b-44b1-a097-2f3df84c6158
https://ora.ox.ac.uk/objects/uuid:8836bf2a-5f5b-44b1-a097-2f3df84c6158
Autor:
Tanatorn, Khotavivattana, Samuel, Calderwood, Stefan, Verhoog, Lukas, Pfeifer, Sean, Preshlock, Neil, Vasdev, Thomas L, Collier, Véronique, Gouverneur
Publikováno v:
Organic letters. 19(3)
In this work, we describe the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1e5af7d5a8ad7af73f3db00296b98e9
https://pubmed.ncbi.nlm.nih.gov/28085289
https://pubmed.ncbi.nlm.nih.gov/28085289
Autor:
Faye Buckingham, Ian Martin Newington, Matthias Glaser, Véronique Gouverneur, Thomas Keller, Thomas Lee Collier, Begoña Checa, Samuel Calderwood, Rajiv Bhalla, Matthew Tredwell
Publikováno v:
ChemInform. 47
We report a late stage oxidative nucleophilic fluorination of N-arylsulfonamides, a class of compounds so far not considered as precursors to 4-fluorophenyl sulfonamides. By installing a para-positioned tert-butyl substituent on the aniline, oxidativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffba91115ad6cad39afa8b5907e2edcf
https://doi.org/10.1002/chin.201613079
https://doi.org/10.1002/chin.201613079
Autor:
Thomas Cailly, Alexander Hoepping, Véronique Gouverneur, Thomas C. Wilson, Jan Mollitor, Samuel Calderwood, Joël Mercier, Thomas Lee Collier, Michael Schedler, Mickael Huiban, Stefan Gruber, Marco Mueller, René Smits, Nicholas J. Taylor, Stefan Verhoog, Matthew Tredwell, Sean Preshlock, Christophe Genicot, Jan Passchier, Antje Hienzsch
Publikováno v:
Chemical Communications
Chemical Communications, Royal Society of Chemistry, 2016, 52 (54), pp.8361-8364. ⟨10.1039/C6CC03295H⟩
Chemical Communications, Royal Society of Chemistry, 2016, 52 (54), pp.8361-8364. ⟨10.1039/C6CC03295H⟩
International audience; [18F]FMTEB, [18F]FPEB, [18F]flumazenil, [18F]DAA1106, [18F]MFBG, [18F]FDOPA, [18F]FMT and [18F]FDA are prepared from the corresponding arylboronic esters and [18F]KF/K222 in the presence of Cu(OTf)2py4. The method was successf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::642f41473c810fbe8b1fb8a2138086fa
https://hal.archives-ouvertes.fr/hal-02011096
https://hal.archives-ouvertes.fr/hal-02011096
Spirocyclic hypervalent iodine(III) ylides have proven to be synthetically versatile precursors for efficient radiolabelling of a diverse range of non-activated (hetero)arenes, highly functionalised small molecules, building blocks and radiopharmaceu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aab9985fe4c4fa584e5026f7e9c49c6
https://europepmc.org/articles/PMC4976495/
https://europepmc.org/articles/PMC4976495/
Autor:
Jack Twilton, Benoit Liegault, Véronique Gouverneur, Marc Taillefer, Samuel Calderwood, Enrico Emer, Thomas Lee Collier, Matthew Tredwell
Publikováno v:
ChemInform. 46
The reaction of various (diazotrifluoroethyl)arenes with HF, F/Br, F2, CF3H, and CF3SH sources give direct access to a variety of perfluoroalkyl-substituted arenes presenting with incremental fluorine content.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e8afb3e36ca1fe97659c0cba1aada55
https://doi.org/10.1002/chin.201518079
https://doi.org/10.1002/chin.201518079