Need-based prioritization of behavior

Autor: C Joseph Burnett, Samuel C Funderburk, Jovana Navarrete, Alexander Sabol, Jing Liang-Guallpa, Theresa M Desrochers, Michael J Krashes

Publikováno v: eLife, Vol 8 (2019)

When presented with a choice, organisms need to assimilate internal information with external stimuli and past experiences to rapidly and flexibly optimize decisions on a moment-to-moment basis. We hypothesized that increasing hunger intensity would

Externí odkaz: https://doaj.org/article/a5a24a4ddced457c846ae0e880b949ba

An essential role for a discrete parasubthalamic nucleus subpopulation in appetite suppression

Autor: Matthew C Newman, Kenneth Han, Jacob Sperber, Sierra Loomis, Michael J. Krashes, Grace H. Kromm, Faris F Gulamali, Olivia K Barnhill, Matthew E. Carter, Jessica H. Kim, Theresa B Legan, Katharine Jensen, Samuel C. Funderburk, Lauren B Heuer

Food intake behavior is regulated by a network of appetite-inducing and appetite-suppressing neuronal populations throughout the brain. The parasubthalamic nucleus (PSTN), a relatively unexplored population of neurons in the posterior hypothalamus, h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b766332b36988fb46a5ac85e6c30e15c
https://doi.org/10.1101/2021.11.10.468058

Author response: Need-based prioritization of behavior

Autor: Jing Liang-Guallpa, Michael J. Krashes, Alexander Sabol, Samuel C. Funderburk, Jovana Navarrete, Theresa M. Desrochers, C. Joseph Burnett

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::61fbd79829bbc65cb05738512618eace
https://doi.org/10.7554/elife.44527.024

MCH Regulates SIRT1/FoxO1 and Reduces POMC Neuronal Activity to Induce Hyperphagia, Adiposity, and Glucose Intolerance

Autor: Carlos Dieguez, Miguel López, René Hernández-Bautista, Jerome Clasadonte, Giles S.H. Yeo, Melissa J. Chee, Donald A. Morgan, Zsolt Liposits, Brian Y.H. Lam, Serge Luquet, Rubén Nogueiras, Violeta Heras, Kamal Rahmouni, Amparo Romero-Picó, Miguel Fidalgo, Imre Kalló, Samuel C. Funderburk, Michael J. Krashes, Omar Al-Massadi, Lucía García-Caballero, Monica Imbernon, Ana Senra, Mar Quiñones, Cintia Folgueira, Daniel Beiroa, Vincent Prevot, Yara Souto, Rosalía Gallego

Publikováno v: Diabetes
Diabetes, 2019, 68 (12), pp.2210-2222. ⟨10.2337/db19-0029⟩
Diabetes, American Diabetes Association, 2019, 68 (12), pp.2210-2222. ⟨10.2337/db19-0029⟩

International audience; Melanin-concentrating hormone (MCH) is an important regulator of food intake, glucose metabolism, and adiposity. However, the mechanisms mediating these actions remain largely unknown. We used pharmacological and genetic appro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76545f4800ce64363ac0ed9bed35ca61

A GABAergic Projection from the Centromedial Nuclei of the Amygdala to Ventromedial Prefrontal Cortex Modulates Reward Behavior

Autor: Dionnet L. Bhatti, Dong Oh Seo, Dillan J. Newbold, Dennis R. Sparta, Kasey S. Girven, Michael R. Bruchas, Samuel C. Funderburk, Michael J. Krashes, Laura E. Motard, Jordan G. McCall

The neural circuitry underlying mammalian reward behaviors involves several distinct nuclei throughout the brain. It is widely accepted that the midbrain dopamine (DA) neurons are critical for the reward-related behaviors. Recent studies have shown t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d1e8883bd9f9145f96312c0fae9de5
https://europepmc.org/articles/PMC5083011/