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of 3
pro vyhledávání: '"Samuel C. Agius"'
Autor:
Evan Healy, Qi Zhang, Emma H. Gail, Samuel C. Agius, Guizhi Sun, Michael Bullen, Varun Pandey, Partha Pratim Das, Jose M. Polo, Chen Davidovich
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113858- (2024)
Summary: RNA has been implicated in the recruitment of chromatin modifiers, and previous studies have provided evidence in favor and against this idea. RNase treatment of chromatin is commonly used to study RNA-mediated regulation of chromatin modifi
Externí odkaz:
https://doaj.org/article/88dbe8b8c5604e04891cc64837a90818
Autor:
Qi Zhang, Samuel C. Agius, Sarena F. Flanigan, Michael Uckelmann, Vitalina Levina, Brady M. Owen, Chen Davidovich
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
The polycomb repressive complex 2 (PRC2) is a histone methyltransferase regulating cell differentiation and identity. Here, the authors show that the vertebrate-specific PRC2 accessory subunit PALI1 facilitates substrate binding by the complex and el
Externí odkaz:
https://doaj.org/article/28e111a4e42249e7b0c766b5a9d29549
Autor:
Brady M. Owen, Samuel C. Agius, Vitalina Levina, Chen Davidovich, Sarena F. Flanigan, Michael Uckelmann, Qi Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Nature Communications
The polycomb repressive complex 2 (PRC2) is a histone methyltransferase that maintains cell identities. JARID2 is the only accessory subunit of PRC2 that known to trigger an allosteric activation of methyltransferase. Yet, this mechanism cannot be ge