Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Samuel C Y Leung"'
Autor:
Karama Asleh, Nazia Riaz, Angela S. Cheng, Dongxia Gao, Samuel C. Y. Leung, Meenakshi Anurag, Torsten O. Nielsen
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract Precise biomarkers are needed to guide better diagnostics and therapeutics for basal-like breast cancer, for which DNA-dependent protein kinase catalytic subunit (DNA-PKcs) has been recently reported by the Clinical Proteomic Tumor Analysis
Externí odkaz:
https://doaj.org/article/50da77342af4406d9748983cb7210dc1
Publikováno v:
APMIS. 129:489-502
Background We analysed the reproducibility of Ki67 labelling index (LI) between two scorers using the International Ki67 Working Group (IKWG) global methods on an Android application (APP), correlated the APP and eyeball estimate (EBE) with digital i
Autor:
Samuel C Y Leung, Dongxia Gao, Samantha Burugu, Torsten O. Nielsen, Angela S. Cheng, Nazia Riaz
Publikováno v:
Cancers
Volume 13
Issue 22
Cancers, Vol 13, Iss 5769, p 5769 (2021)
Volume 13
Issue 22
Cancers, Vol 13, Iss 5769, p 5769 (2021)
Colony-stimulating factor-1 receptor (CSF-1R) signaling promotes an immune suppressive microenvironment enriched in M2 macrophages. Given that CSF-1R inhibitors are under investigation in clinical trials, including in breast cancer, CSF-1R expression
Autor:
Samantha Burugu, Angela S. Cheng, Torsten O. Nielsen, Matthew J. Ellis, Meenakshi Anurag, Dongxia Gao, Samuel C Y Leung
Publikováno v:
Breast Cancer Research and Treatment
Purpose Alterations to mismatch repair (MMR) pathways are a known cause of cancer, particularly colorectal and endometrial carcinomas. Recently, checkpoint inhibitors have been approved for use in MMR-deficient cancers of any type (Prasad et al. in J
Autor:
Giuseppe Viale, Zuzana Kos, Allen M Gown, John M. S. Bartlett, Samuel C Y Leung, Andrew Dodson, Dongxia Gao, Frédérique Penault-Llorca, Jane Starczynski, Roberto Salgado, Mauro G. Mastropasqua, Sharon Nofech-Mozes, C. Kent Osborne, Signe Borgquist, Mitch Dowsett, Bert van der Vegt, Torsten O. Nielsen, Takuya Moriya, Takashi Sakatani, Tammy Piper, Carolina Gutierrez, Tomoharu Sugie, Anita Bane, Martin C. Chang, Susan Fineberg, Cornelia M Focke, Lila Zabaglo, Anna Ehinger, Lisa M. McShane, Sunil Badve, Daniel F. Hayes, Judith Hugh, Anne-Vibeke Lænkholm, Indu Arun
Publikováno v:
Histopathology, 75(2), 225-235. Wiley
Leung, S C Y, Nielsen, T O, Zabaglo, L A, Arun, I, Badve, S S, Bane, A L, Bartlett, J M S, Borgquist, S, Chang, M C, Dodson, A, Ehinger, A, Fineberg, S, Focke, C M, Gao, D, Gown, A M, Gutierrez, C, Hugh, J C, Kos, Z, Lænkholm, A, Mastropasqua, M G, Moriya, T, Nofech-mozes, S, Osborne, C K, Penault-llorca, F M, Piper, T, Sakatani, T, Salgado, R, Starczynski, J, Sugie, T, Vegt, B, Viale, G, Hayes, D F, Mcshane, L M & Dowsett, M 2019, ' Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicentre collaboration ', Histopathology . https://doi.org/10.1111/his.13880
Leung, S C Y, Nielsen, T O, Zabaglo, L A, Arun, I, Badve, S S, Bane, A L, Bartlett, J M S, Borgquist, S, Chang, M C, Dodson, A, Ehinger, A, Fineberg, S, Focke, C M, Gao, D, Gown, A M, Gutierrez, C, Hugh, J C, Kos, Z, Lænkholm, A V, Mastropasqua, M G, Moriya, T, Nofech-Mozes, S, Osborne, C K, Penault-Llorca, F M, Piper, T, Sakatani, T, Salgado, R, Starczynski, J, Sugie, T, van der Vegt, B, Viale, G, Hayes, D F, McShane, L M, Dowsett, M & on behalf of the International Ki67 in Breast Cancer Working Group of the Breast International Group and North American Breast Cancer Group (BIG-NABCG) 2019, ' Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections : an international multicentre collaboration ', Histopathology, vol. 75, no. 2, pp. 225-235 . https://doi.org/10.1111/his.13880
Leung, S C Y, Nielsen, T O, Zabaglo, L A, Arun, I, Badve, S S, Bane, A L, Bartlett, J M S, Borgquist, S, Chang, M C, Dodson, A, Ehinger, A, Fineberg, S, Focke, C M, Gao, D, Gown, A M, Gutierrez, C, Hugh, J C, Kos, Z, Lænkholm, A, Mastropasqua, M G, Moriya, T, Nofech-mozes, S, Osborne, C K, Penault-llorca, F M, Piper, T, Sakatani, T, Salgado, R, Starczynski, J, Sugie, T, Vegt, B, Viale, G, Hayes, D F, Mcshane, L M & Dowsett, M 2019, ' Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicentre collaboration ', Histopathology . https://doi.org/10.1111/his.13880
Leung, S C Y, Nielsen, T O, Zabaglo, L A, Arun, I, Badve, S S, Bane, A L, Bartlett, J M S, Borgquist, S, Chang, M C, Dodson, A, Ehinger, A, Fineberg, S, Focke, C M, Gao, D, Gown, A M, Gutierrez, C, Hugh, J C, Kos, Z, Lænkholm, A V, Mastropasqua, M G, Moriya, T, Nofech-Mozes, S, Osborne, C K, Penault-Llorca, F M, Piper, T, Sakatani, T, Salgado, R, Starczynski, J, Sugie, T, van der Vegt, B, Viale, G, Hayes, D F, McShane, L M, Dowsett, M & on behalf of the International Ki67 in Breast Cancer Working Group of the Breast International Group and North American Breast Cancer Group (BIG-NABCG) 2019, ' Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections : an international multicentre collaboration ', Histopathology, vol. 75, no. 2, pp. 225-235 . https://doi.org/10.1111/his.13880
Aims: The nuclear proliferation marker Ki67 assayed by immunohistochemistry has multiple potential uses in breast cancer, but an unacceptable level of interlaboratory variability has hampered its clinical utility. The International Ki67 in Breast Can
Autor:
Tammy Piper, Joema Lima, Anita Bane, Daniel F. Hayes, Chad Galderisi, Mitch Dowsett, Lisa M. McShane, Keith W. Miller, Jason Ruan, Samuel C Y Leung, Martin C. Chang, David L. Rimm, Torsten O. Nielsen, Malini Srinivasan, Yalai Bai, Shakeel Virk, John M. S. Bartlett, Hua Yang, Carsten Denkert, Michelle Dean, Judith Hugh, Richard M. Levenson, Emeka K. Enwere, Arvydas Laurinavicius, Ying Wu, Elizabeth N. Kornaga, Abhi Gholap, Anagha P. Jadhav, Liron Pantanowitz, Jane Bayani
Publikováno v:
Modern Pathology. 32:59-69
The nuclear proliferation biomarker Ki67 has potential prognostic, predictive, and monitoring roles in breast cancer. Unacceptable between-laboratory variability has limited its clinical value. The International Ki67 in Breast Cancer Working Group in
Publikováno v:
J Natl Cancer Inst
Autor:
Samuel C Y Leung, Torsten O. Nielsen, Shoukat Dedhar, Dongxia Gao, Shawn C. Chafe, Nazia Riaz, Samantha Burugu, Anna F. Lee, Cheng-Han Lee
Publikováno v:
Cancers
Volume 13
Issue 5
Cancers, Vol 13, Iss 1022, p 1022 (2021)
Volume 13
Issue 5
Cancers, Vol 13, Iss 1022, p 1022 (2021)
Simple Summary Preclinical studies suggest that interactions between granulocyte colony-stimulating factor (G-CSF) and hypoxia-induced carbonic anhydrase IX regulate the trafficking and function of immune cells in the tumour microenvironment. We inve
Autor:
Torsten O Nielsen, Samuel C. Y Leung, David L Rimm, Andrew Dodson, Balazs Acs, Sunil Badve, Carsten Denkert, Matthew J Ellis, Susan Fineberg, Margaret Flowers, Hans H Kreipe, Anne-Vibeke Laenkholm, Hongchao Pan, Frédérique M Penault-Llorca, Mei-Yin Polley, Roberto Salgado, Ian E Smith, Tomoharu Sugie, John M. S Bartlett, Lisa M McShane, Mitch Dowsett, Daniel F Hayes
Publikováno v:
O Nielson, T, C. Y. Leung, S, L. Rimm, D, Dodson, A, Acs, B, Badve, S, Denkert, C, J. Ellis, M, Fineberg, S, Flowers, M, H. Kreipe, H, Laenkholm, A-V, Pan, H, M Penault-Llorca, F, Polley, M-Y, Salgado, R, E. Smith, I, Sugie, T, Bartlett, J, M McShane, L, Dowsett, M & F Hayes, D 2020, ' Assessment of Ki67 in Breast Cancer: Updated Recommendations from the International Ki67 in Breast Cancer Working Group ', JNCI: Journal of the National Cancer Institute .
Nielsen, T O, Leung, S C Y, Rimm, D L, Dodson, A, Acs, B, Badve, S, Denkert, C, Ellis, M J, Fineberg, S, Flowers, M, Kreipe, H H, Laenkholm, A-V, Pan, H, Penault-Llorca, F M, Polley, M-Y, Salgado, R, Smith, I E, Sugie, T, Bartlett, J M S, McShane, L M, Dowsett, M & Hayes, D F 2021, ' Assessment of Ki67 in Breast Cancer : Updated Recommendations from the International Ki67 in Breast Cancer Working Group ', JNCI-Journal of the National Cancer Institute, vol. 113, no. 7, pp. 808–819 . https://doi.org/10.1093/jnci/djaa201
JNCI: Journal of the National Cancer Institute
JNCI: Journal of the National Cancer Institute, Oxford University Press (OUP), 2020, ⟨10.1093/jnci/djaa201⟩
JNCI Journal of the National Cancer Institute
Nielsen, T O, Leung, S C Y, Rimm, D L, Dodson, A, Acs, B, Badve, S, Denkert, C, Ellis, M J, Fineberg, S, Flowers, M, Kreipe, H H, Laenkholm, A-V, Pan, H, Penault-Llorca, F M, Polley, M-Y, Salgado, R, Smith, I E, Sugie, T, Bartlett, J M S, McShane, L M, Dowsett, M & Hayes, D F 2021, ' Assessment of Ki67 in Breast Cancer : Updated Recommendations from the International Ki67 in Breast Cancer Working Group ', JNCI-Journal of the National Cancer Institute, vol. 113, no. 7, pp. 808–819 . https://doi.org/10.1093/jnci/djaa201
JNCI: Journal of the National Cancer Institute
JNCI: Journal of the National Cancer Institute, Oxford University Press (OUP), 2020, ⟨10.1093/jnci/djaa201⟩
JNCI Journal of the National Cancer Institute
Ki67 immunohistochemistry (IHC), commonly used as a proliferation marker in breast cancer, has limited value for treatment decisions due to questionable analytical validity. The International Ki67 in Breast Cancer Working Group (IKWG) consensus meeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227f30de237b3711dc943d6d1f587ec7
https://www.pure.ed.ac.uk/ws/files/192560507/djaa201_published.pdf
https://www.pure.ed.ac.uk/ws/files/192560507/djaa201_published.pdf
Autor:
Samuel C Y Leung, Meenakshi Anurag, Dongxia Gao, Angela S. Cheng, Samantha Burugu, Matthew J. Ellis, Torsten O. Nielsen
Publikováno v:
Breast Cancer Res Treat
In the original publication of the article, the funding statement was published incompletely. The corrected funding statement should read as below.