Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Samuel C Nash"'
Autor:
David Longmire, Haley Woods, Phillip B Rawlins, Jessie Hao-Ru Hsu, Daniel H O' Donovan, Alexandra Borodovsky, Peng Wang, Sharan K Bagal, Shaun M Fillery, Peter Barton, Clare Gregson, Beth Williamson, Samuel C Nash, Andrew Pike, Jon A Read, Kurt Gordon Pike, Andrew Bloecher, Erin Code, Minhui Shen, Sameer Kawatkar, Youfeng Nai, Jia Tang, Chengzhi Li, James C. Robinson
Publikováno v:
Journal of Medicinal Chemistry. 64:17146-17183
Aberrant activity of the histone methyltransferase polycomb repressive complex 2 (PRC2) has been linked to several cancers, with small-molecule inhibitors of the catalytic subunit of the PRC2 enhancer of zeste homologue 2 (EZH2) being recently approv
Autor:
Akosua B. Anane-Adjei, Esther Jacobs, Samuel C. Nash, Sean Askin, Ramesh Soundararajan, Mary Kyobula, Jonathan Booth, Andrew Campbell
Publikováno v:
International journal of pharmaceutics. 614
The poor aqueous solubility of many active pharmaceutical ingredients (APIs) dominates much of the early drug development portfolio and poses a major challenge in pharmaceutical development. Polymer-based amorphous solid dispersions (ASDs) are becomi