Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Samuel C J Redstone"'
Publikováno v:
Chemical Research in Toxicology. 32:437-446
Because of its low redox potential, guanine (G) is the most frequent site of oxidation in the genome. Metabolic processes generate reactive oxygen species (ROS) that can oxidize G to yield 8-oxo-7,8-dihydroguanine (OG) as a key two-electron oxidation
Publikováno v:
Toxicology and Applied Pharmacology. 352:19-27
The bifunctional alkylating agents epichlorohydrin (ECH) and diepoxybutane (DEB) have been linked to increased cancer risks in industrial workers. These compounds react with DNA and proteins, leading to genotoxic effects. We used the comet assay to m
Publikováno v:
The FASEB Journal. 29