Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Samuel Bremang"'
Autor:
Ann-Kathrin Reuschl, Michael R Edwards, Robert Parker, David W Connell, Long Hoang, Alice Halliday, Hannah Jarvis, Nazneen Siddiqui, Corrina Wright, Samuel Bremang, Sandra M Newton, Peter Beverley, Robin J Shattock, Onn Min Kon, Ajit Lalvani
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006577 (2017)
Early events in the human airways determining whether exposure to Mycobacterium tuberculosis (Mtb) results in acquisition of infection are poorly understood. Epithelial cells are the dominant cell type in the lungs, but little is known about their ro
Externí odkaz:
https://doaj.org/article/fd0f69a47d2a4fb2997324cd9f4d0a6a
Autor:
Suzanne M. Hingley-Wilson, Rosalyn Casey, David Connell, Samuel Bremang, Jason T. Evans, Peter M. Hawkey, Grace E. Smith, Annette Jepson, Stuart Philip, Onn Min Kon, Ajit Lalvani
Publikováno v:
Emerging Infectious Diseases, Vol 19, Iss 7, Pp 1138-1141 (2013)
Infections with >1 Mycobacterium tuberculosis strain(s) are underrecognized. We show, in vitro and in vivo, how first-line treatment conferred a competitive growth advantage to amplify a multidrug-resistant M. tuberculosis strain in a patient with mi
Externí odkaz:
https://doaj.org/article/5f72ad35721e4da483bbe6b8dc4c7ed4
Autor:
Rosalyn Casey, Deena Blumenkrantz, Kerry Millington, Damien Montamat-Sicotte, Onn Min Kon, Melissa Wickremasinghe, Samuel Bremang, Murphy Magtoto, Saranya Sridhar, David Connell, Ajit Lalvani
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15619 (2010)
IFN-γ and IL-2 cytokine-profiles define three functional T-cell subsets which may correlate with pathogen load in chronic intracellular infections. We therefore investigated the feasibility of the immunospot platform to rapidly enumerate T-cell subs
Externí odkaz:
https://doaj.org/article/f30a0323bdb14f8881cb6d6f70bbcdfb
Autor:
Seran Hakki, Jie Zhou, Jakob Jonnerby, Anika Singanayagam, Jack L Barnett, Kieran J Madon, Aleksandra Koycheva, Christine Kelly, Hamish Houston, Sean Nevin, Joe Fenn, Rhia Kundu, Michael A Crone, Timesh D Pillay, Shazaad Ahmad, Nieves Derqui-Fernandez, Emily Conibear, Paul S Freemont, Graham P Taylor, Neil Ferguson, Maria Zambon, Wendy S Barclay, Jake Dunning, Ajit Lalvani, Anjna Badhan, Robert Varro, Constanta Luca, Valerie Quinn, Jessica Cutajar, Niamh Nichols, Jessica Russell, Holly Grey, Anjeli Ketkar, Giulia Miserocchi, Chitra Tejpal, Harriet Catchpole, Koji Nixon, Berenice Di Biase, Tamara Hopewell, Janakan Sam Narean, Jada Samuel, Kristel Timcang, Eimear McDermott, Samuel Bremang, Sarah Hammett, Samuel Evetts, Alexandra Kondratiuk
Publikováno v:
The Lancet Respiratory Medicine. 10:1061-1073
Background Knowledge of the window of SARS-CoV-2 infectiousness is crucial in developing policies to curb transmission. Mathematical modelling based on scarce empirical evidence and key assumptions has driven isolation and testing policy, but real-wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da97bca4801e068b116493e9d1eb639a
https://doi.org/10.1016/s2213-2600(22)00226-0
https://doi.org/10.1016/s2213-2600(22)00226-0
Autor:
Nieves Derqui, Aleksandra Koycheva, Jie Zhou, Timesh D Pillay, Michael A Crone, Seran Hakki, Joe Fenn, Rhia Kundu, Robert Varro, Emily Conibear, Kieran J Madon, Jack L Barnett, Hamish Houston, Anika Singanayagam, Janakan S Narean, Mica R Tolosa-Wright, Lucy Mosscrop, Carolina Rosadas, Patricia Watber, Charlotte Anderson, Eleanor Parker, Paul S Freemont, Neil M Ferguson, Maria Zambon, Myra O McClure, Richard Tedder, Wendy S Barclay, Jake Dunning, Graham P Taylor, Ajit Lalvani, Jessica Cutajar, Valerie Quinn, Sarah Hammett, Eimèar McDermott, Constanta Luca, Kristel Timcang, Jada Samuel, Samuel Bremang, Samuel Evetts, Lulu Wang, Sean Nevin, Megan Davies, Chitra Tejpal, Mohammed Essoussi, Anjeli V Ketkar, Giulia Miserocchi, Harriet Catchpole, Anjna Badhan, Simon Dustan, Isaac J Day Weber, Federica Marchesin, Michael G Whitfield, John Poh, Alexandra Kondratiuk
Publikováno v:
e408
e397
e397
BACKGROUND: Despite circumstantial evidence for aerosol and fomite spread of SARS-CoV-2, empirical data linking either pathway with transmission are scarce. Here we aimed to assess whether the presence of SARS-CoV-2 on frequently-touched surfaces and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85de716b996bdf0a833b483496c56886
http://hdl.handle.net/10044/1/104998
http://hdl.handle.net/10044/1/104998
Autor:
Jake Dunning, Joanna Ellis, Samuel Evetts, Ajit Lalvani, Michael A. Crone, Timesh D Pillay, Sarah Hammett, Samuel Bremang, Michael G Whitfield, David C. Jackson, Chitra Tejpal, Charlotte Anderson, Anjna Badhan, Wendy S. Barclay, Angie Lackenby, Maria Zambon, Aleksandra Koycheva, Graham P. Taylor, J. S. Narean, Neil M. Ferguson, Nieves Derqui-Fernandez, Anika Singanayagam, Rhia Kundu, Constanta Luca, Joe Fenn, Simon Dustan, Valerie Quinn, Shazaad Ahmad, Jada Samuel, Kieran J Madon, Anjeli V Ketkar, Jessica Cutajar, Paul S. Freemont, Andre Charlett, Seran Hakki, Emily Conibear, Jack L Barnett, Hamish Houston, Eimear McDermott, Robert Varro, John Poh, Shahjahan Miah
Publikováno v:
The Lancet. Infectious Diseases
Background The SARS-CoV-2 delta (B.1.617.2) variant is highly transmissible and spreading globally, including in populations with high vaccination rates. We aimed to investigate transmission and viral load kinetics in vaccinated and unvaccinated indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cb5ae0c9be58dd1345e661d61e7616
http://europepmc.org/articles/PMC8554486
http://europepmc.org/articles/PMC8554486
Autor:
Jake Dunning, Samuel Bremang, R. Varro, Vetkar A, Dustan S, Derqui-Fernandez N, Graham P. Taylor, J. Fenn, R. Kundu, Quinn, Hammett S, Ajit Lalvani, Joanna Ellis, J. S. Narean, Koycheva A, David C. Jackson, Timesh D Pillay, Miah S, Anjna Badhan, Emily Conibear, Andre Charlett, Hakki S, Wendy S. Barclay, Madon Kj, Hamish Houston, Samuel J, Anderson C, Paul S. Freemont, C. Tejpal, Angie Lackenby, Maria Zambon, Cutajar J, Jake Barnett, Michael A. Crone, Whitfield Mg, McDermott E, Luca C, Neil M. Ferguson, Shazaad Ahmad, Aran Singanayagam
Publikováno v:
SSRN Electronic Journal.
Background: The SARS-CoV-2 Delta variant is highly transmissible and spreading globally but a detailed understanding of community transmission risks in highly vaccinated populations is lacking. Methods: Between September 2020 and August 2021, we recr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d57835937676697c3c866dd04d416e6f
https://doi.org/10.2139/ssrn.3918287
https://doi.org/10.2139/ssrn.3918287
Autor:
Michael R. Edwards, Ann-Kathrin Reuschl, Corrina Wright, Peter Beverley, Ajit Lalvani, Robin J. Shattock, Robert Parker, Sandra M. Newton, Samuel Bremang, D W Connell, Hannah Jarvis, Nazneen Siddiqui, Onn Min Kon, Long Hoang, Alice Halliday
Publikováno v:
Reuschl, A-K, Edwards, M, Parker, R, Connell, D, Hoang, L, Halliday, A, Jarvis, H, Siddiqui, N, Wright, C, Bremang, S, Newton, S, Beverley, P, Shattock, R, Kon, O M & Lalvani, A 2017, ' Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways ', PLoS Pathogens, vol. 13, no. 9, e1006577 . https://doi.org/10.1371/journal.ppat.1006577
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 9, p e1006577 (2017)
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 9, p e1006577 (2017)
Early events in the human airways determining whether exposure to Mycobacterium tuberculosis (Mtb) results in acquisition of infection are poorly understood. Epithelial cells are the dominant cell type in the lungs, but little is known about their ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67391a170cb171a9c389f6b2d6437ece
https://research-information.bris.ac.uk/ws/files/183274232/journal.ppat.1006577.pdf
https://research-information.bris.ac.uk/ws/files/183274232/journal.ppat.1006577.pdf
Autor:
Umar Niazi, Onn Min Kon, Heinke Kunst, Sarah Menzies, Peter Beverley, Hilary S. Whitworth, Alice Halliday, Samuel Bremang, Sherine Hermagild Kottoor, Amarjit Badhan, Ajit Lalvani
Publikováno v:
The Journal of Infectious Diseases
Halliday, A, Whitworth, H, Hermagild Kottoor, S, Niazi, U, Menzies, S, Kunst, H, Bremang, S, Badhan, A, Beverley, P, Kon, O M & Lalvani, A 2017, ' Stratification of latent Mycobacterium tuberculosis infection by cellular immune profiling ', Journal of Infectious Diseases, vol. 215, no. 9, pp. 1480–1487 . https://doi.org/10.1093/infdis/jix107
Halliday, A, Whitworth, H, Hermagild Kottoor, S, Niazi, U, Menzies, S, Kunst, H, Bremang, S, Badhan, A, Beverley, P, Kon, O M & Lalvani, A 2017, ' Stratification of latent Mycobacterium tuberculosis infection by cellular immune profiling ', Journal of Infectious Diseases, vol. 215, no. 9, pp. 1480–1487 . https://doi.org/10.1093/infdis/jix107
Summary Persons with latent Mycobacterium tuberculosis infection (LTBI) vary by their risk of progression to tuberculosis but are clinically indistinguishable. We identified a cellular immune signature that correlates strongly with time since exposur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4972c0b2d476b46818d674e2f8a98f
Autor:
Ajit Lalvani, Jason T. Evans, Rosalyn Casey, D W Connell, Annette Jepson, Samuel Bremang, Suzanne M. Hingley-Wilson, Stuart Philip, Onn Min Kon, Grace Smith, Peter M. Hawkey
Publikováno v:
Emerging Infectious Diseases
Emerging Infectious Diseases, Vol 19, Iss 7, Pp 1138-1141 (2013)
Emerging Infectious Diseases, Vol 19, Iss 7, Pp 1138-1141 (2013)
Infections with >1 Mycobacterium tuberculosis strain(s) are underrecognized. We show, in vitro and in vivo, how first-line treatment conferred a competitive growth advantage to amplify a multidrug-resistant M. tuberculosis strain in a patient with mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db547112248e82842d2ab81e5b6a4da4
https://doi.org/10.3201/eid1907.130313
https://doi.org/10.3201/eid1907.130313