Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Samuel Botterbusch"'
Autor:
Samsuzzoha Mondal, Karthik Narayan, Samuel Botterbusch, Imania Powers, Jason Zheng, Honey Priya James, Rui Jin, Tobias Baumgart
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Here the authors show that protein phase separation is a key mechanism in cellular receptor internalization via fast endophilin mediated endocytosis (FEME). Phase separation facilitates multivalent FEME-protein assembly in this clathrin-independent p
Externí odkaz:
https://doaj.org/article/eb88be9e379b4997bb94720b21511499
Autor:
Samuel Botterbusch, Tobias Baumgart
Publikováno v:
Applied Sciences, Vol 11, Iss 3, p 1288 (2021)
Liquid-liquid phase separation has recently emerged as an important fundamental organizational phenomenon in biological settings. Most studies of biological phase separation have focused on droplets that “condense” from solution above a critical
Externí odkaz:
https://doaj.org/article/ff455175a4fb4a9cada3f2f55fa52137
Autor:
David C. Metz, Shria Kumar, Jason M. Heckert, Bryson W. Katona, Caroline Creamer, Alice Alderson, Bonita Bennett, Jennifer R. Eads, Sarit T. Kipnis, Daniel A. Pryma, David A. Mankoff, Michael C. Soulen, Samuel Botterbusch
Publikováno v:
Oncologist
Background Peptide receptor radionuclide therapy (PRRT) is effective for treating midgut neuroendocrine tumors (NETs); however, incorporation of PRRT into routine practice in the U.S. is not well studied. Herein we analyze the first year of PRRT impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af39735e133fee8cc259faad6a15a413
https://doi.org/10.1634/theoncologist.2019-0743
https://doi.org/10.1634/theoncologist.2019-0743
Autor:
Samsuzzoha Mondal, Karthik Narayan, Samuel Botterbusch, Imania Powers, Jason Zheng, Honey Priya James, Rui Jin, Tobias Baumgart
A specific group of transmembrane receptors, including the β1-adrenergic receptor (β1-AR), is internalized through a non-clathrin pathway known as Fast Endophilin Mediated Endocytosis (FEME). A key question is: how does the endocytic machinery asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f0f5f80498fb7bbfc19cd19914c1f0
https://doi.org/10.1101/2021.12.27.474257
https://doi.org/10.1101/2021.12.27.474257
Autor:
Tobias Baumgart, Samuel Botterbusch
Publikováno v:
Applied Sciences, Vol 11, Iss 1288, p 1288 (2021)
Applied sciences (Basel, Switzerland)
Applied sciences (Basel, Switzerland)
Liquid-liquid phase separation has recently emerged as an important fundamental organizational phenomenon in biological settings. Most studies of biological phase separation have focused on droplets that “condense” from solution above a critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c7d066196c13fa035b9b6b6120defd
https://www.mdpi.com/2076-3417/11/3/1288
https://www.mdpi.com/2076-3417/11/3/1288
The Bin/Amphiphysin/Rvs (BAR) family protein endophilin plays key roles in membrane curvature generation during endocytosis of cellular receptors. The Src homology 3 (SH3) domain of endophilin interacts with the proline rich third intracellular loop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c37a30bc1e356e0589705b26eab12566
https://doi.org/10.1101/2020.07.11.198937
https://doi.org/10.1101/2020.07.11.198937
Autor:
Samsuzzoha Mondal, Samuel Botterbusch, Karthik Narayan, Imania Powers, Jason Zheng, Tobias Baumgart
Publikováno v:
Biophysical Journal. 121:80a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5ec277f02e609974301b3876ee17df1
https://doi.org/10.1016/j.bpj.2021.11.2319
https://doi.org/10.1016/j.bpj.2021.11.2319
Publikováno v:
The Journal of Biological Chemistry
Endophilin plays key roles during endocytosis of cellular receptors, including generating membrane curvature to drive internalization. Electrostatic interactions between endophilin’s BIN/Amphiphysin/Rvs domain and anionic membrane lipids have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c40bd9fd7734e426564856243dc5cb7
https://doi.org/10.1074/jbc.ra120.016118
https://doi.org/10.1074/jbc.ra120.016118