Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Samuel Bottani"'
Autor:
Marc Montalà-Flaquer, Clara F. López-León, Daniel Tornero, Akke Mats Houben, Tanguy Fardet, Pascal Monceau, Samuel Bottani, Jordi Soriano
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105680- (2022)
Summary: Neuronal cultures are a prominent experimental tool to understand complex functional organization in neuronal assemblies. However, neurons grown on flat surfaces exhibit a strongly coherent bursting behavior with limited functionality. To ap
Externí odkaz:
https://doaj.org/article/dc1c5d87702f4a6e985c5632b95ad74d
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Experimental and numerical studies have revealed that isolated populations of oscillatory neurons can spontaneously synchronize and generate periodic bursts involving the whole network. Such a behavior has notably been observed for cultured neurons i
Externí odkaz:
https://doaj.org/article/007dcd25e7984f3399ae4ee2693e71bd
Autor:
Renaud Renault, Nirit Sukenik, Stéphanie Descroix, Laurent Malaquin, Jean-Louis Viovy, Jean-Michel Peyrin, Samuel Bottani, Pascal Monceau, Elisha Moses, Maéva Vignes
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0120680 (2015)
In this paper we report the combination of microfluidics, optogenetics and calcium imaging as a cheap and convenient platform to study synaptic communication between neuronal populations in vitro. We first show that Calcium Orange indicator is compat
Externí odkaz:
https://doaj.org/article/cf7b7340567841a0bb9fff3d02159a78
Autor:
Reiner A Veitia, Samuel Bottani
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8201 (2009)
BACKGROUND:The lack of correlation between genome size and organismal complexity is understood in terms of the massive presence of repetitive and non-coding DNA. This non-coding subgenome has long been called "junk" DNA. However, it might have import
Externí odkaz:
https://doaj.org/article/9a53a8a3771844d2818f9a5a0ac174ec
Publikováno v:
Journal of Computational Neuroscience. 49:375-394
We propose a novel phase based analysis with the purpose of quantifying the periodic bursts of activity observed in various neuronal systems. The way bursts are intiated and propagate in a spatial network is still insufficiently characterized. In par
Publikováno v:
Journal of computational neuroscience. 49(4)
We propose a novel phase based analysis with the purpose of quantifying the periodic bursts of activity observed in various neuronal systems. The way bursts are intiated and propagate in a spatial network is still insufficiently characterized. In par
Publikováno v:
The European Physical Journal Special Topics. 227:1015-1028
Cultures of dissociated neurons are an invaluable experimental tool in studying neuronal networks at an intermediate scale in an in vitro controlled physico-chemical environment. Moreover, current micro-fabrication techniques allow the design of a cu
Autor:
Reiner A. Veitia, Samuel Bottani
Publikováno v:
Biological Reviews. 92:953-963
We explore minimalist models of transcription in which we take into account that a cis-regulatory sequence is embedded in, and interacts with, a complex genome. The classical Hill equation is the simplest way to represent a transcriptional response.
Publikováno v:
Frontiers in Neuroscience
Experimental and numerical studies have revealed that isolated populations of oscillatory neurons can spontaneously synchronize and generate periodic bursts involving the whole network. Such a behavior has notably been observed for cultured neurons i
Publikováno v:
Trends in Cell Biology
Trends in Cell Biology, Elsevier, 2017, 27 (4), pp.299-310. ⟨10.1016/j.tcb.2016.11.006⟩
Trends in Cell Biology, Elsevier, 2017, 27 (4), pp.299-310. ⟨10.1016/j.tcb.2016.11.006⟩
International audience; Aging involves a progressive decline of metabolic function and an increased incidence of late-onset degenerative disorders and cancer. To a large extent, these processes are influenced by alterations affecting the integrity of