Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Samuel Beligny"'
Autor:
Ee Lin Wong, Eric Nawrotzky, Christoph Arkona, Boo Geun Kim, Samuel Beligny, Xinning Wang, Stefan Wagner, Michael Lisurek, Dirk Carstanjen, Jörg Rademann
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The oncogene STAT5 is involved in cancer cell proliferation. Here, the authors use STAT5 protein to assemble its own small molecule inhibitors via Mannich ligation (three-component-reactions) and show that the resultant ligands can inhibit the prolif
Externí odkaz:
https://doaj.org/article/2011251d4c4d4f39bd08fae3a0b285a3
Autor:
Xinning Wang, Stefan Wagner, Jörg Rademann, Ee Lin Wong, Eric Nawrotzky, Michael Lisurek, Dirk Carstanjen, Christoph Arkona, Boo Geun Kim, Samuel Beligny
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Protein-templated fragment ligations have been established as a powerful method for the assembly and detection of optimized protein ligands. Initially developed for reversible ligations, the method has been expanded to irreversible reactions enabling
Autor:
Samuel Beligny, André Horatscheck, Jutta Ortwein, Stefan Wagner, Michael Lisurek, Boo Geun Kim, Anja Schütz, Jörg Rademann
Publikováno v:
Angewandte Chemie International Edition. 51:9441-9447
A light switch for phosphotyrosine- recognizing proteins: Irradiation of the bioisosteric benzoylphosphonate suffices to "turn off" the activity of target proteins and to label them covalently. Photoactive bioisosters may find applications in functio
Autor:
Boo Geun Kim, Michael Lisurek, Jörg Rademann, Jutta Ortwein, Stefan Wagner, Anja Schütz, Samuel Beligny, André Horatscheck
Publikováno v:
Angewandte Chemie. 124:9577-9583
Publikováno v:
Angewandte Chemie. 118:1933-1937
Autor:
Jörg Rademann, Samuel Beligny
Publikováno v:
The Power of Functional Resins in Organic Synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f8575eb9ecd9a858205e561f7284921
https://doi.org/10.1002/9783527626175.ch4
https://doi.org/10.1002/9783527626175.ch4
Autor:
Samuel Beligny, Siegfried Blechert
Publikováno v:
ChemInform. 40
Autor:
Siegfried Blechert, Samuel Beligny
Publikováno v:
N-Heterocyclic Carbenes in Synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93563ee0859b17dce8df54a5e07b8b2f
https://doi.org/10.1002/9783527609451.ch1
https://doi.org/10.1002/9783527609451.ch1
Publikováno v:
Angewandte Chemie (International ed. in English). 45(12)
Publikováno v:
Angewandte Chemie; Feb2006, Vol. 118 Issue 12, p1933-1937, 5p