Výsledky vyhledávání - "Samuel B. Pattle"

Akademický článek

Quantitative proteomics identifies tumour matrisome signatures in patients with non-small cell lung cancer

Autor: Helen F. Titmarsh, Alex von Kriegsheim, Jimi C. Wills, Richard A. O’Connor, Kevin Dhaliwal, Margaret C. Frame, Samuel B. Pattle, David A. Dorward, Adam Byron, Ahsan R. Akram

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

IntroductionThe composition and remodelling of the extracellular matrix (ECM) are important factors in the development and progression of cancers, and the ECM is implicated in promoting tumour growth and restricting anti-tumour therapies through mult

Externí odkaz: https://doaj.org/article/7b547f7e40124ff7826557da8efed3d7

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pTDP-43 aggregates accumulate in non-central nervous system tissues prior to symptom onset in amyotrophic lateral sclerosis: a case series linking archival surgical biopsies with clinical phenotypic data

Autor: Samuel B Pattle, Judi O'Shaughnessy, Owen Kantelberg, Olivia M Rifai, Judith Pate, Kristine Nellany, Nadine Hays, Mark J Arends, Mathew H Horrocks, Fergal M Waldron, Jenna M Gregory

Publikováno v: Pattle, S B, O'shaughnessy, J, Kantelberg, O, Rifai, O, Pate, J, Nellany, K, Hays, N, Arends, M J, Horrocks, M H, Waldron, F & Gregory, J M 2023, ' pTDP-43 aggregates accumulate in non-central nervous system tissues prior to symptom onset in amyotrophic lateral sclerosis; a case series linking archival surgical biopsies with clinical phenotypic data ', Journal of Pathology, vol. 9, no. 1, pp. 44-55 . https://doi.org/10.1002/cjp2.297

Neurodegenerative diseases such as Parkinson's disease (PD), Alzheimer's disease (AD), and amyotrophic lateral sclerosis (ALS) are traditionally considered strictly neurological disorders. However, clinical presentation is not restricted to neurologi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0800f538b7c48aeac54bbdcedc373c0
https://pubmed.ncbi.nlm.nih.gov/36226890

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pTDP-43 aggregates accumulate in the gut and other non-central nervous system tissues prior to symptom onset in amyotrophic lateral sclerosis

Autor: Samuel B. Pattle, Judi O’Shaughnessy, Olivia M. Rifai, Judith Pate, Mark J. Arends, Fergal M. Waldron, Jenna M. Gregory

ObjectiveNeurodegenerative diseases such as Parkinson’s disease (PD), Alzheimer’s disease (AD) and amyotrophic lateral sclerosis (ALS) are traditionally considered strictly neurological disorders. However, clinical presentation is not restricted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0cb88cc4b720df2d43deb50813cda384
https://doi.org/10.1101/2022.03.17.484805

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Copy number gain of 11q13.3 genes associates with pathological stage in hypopharyngeal squamous cell carcinoma

Autor: Lucy Wells, Simon G. Talbot, Kate Cuschieri, Elizabeth Junor, Samuel B Pattle, Brendan Conn, Athena Togo, Ingolfur Johannessen, Natasa Utjesanovic, Hannah Monaghan

Publikováno v: Genes, Chromosomes and Cancer. 56:185-198

Squamous cell carcinomas of the hypopharynx (HPSCC) and oropharynx (OPSCC) have markedly different patient outcomes. Differences in HPV prevalence between these two patient groups may account for some of this difference, but other molecular markers o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aa7602d294a933a90f75281b3d6d3853
https://doi.org/10.1002/gcc.22425

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Copy number gain of 11q13.3 genes associates with pathological stage in hypopharyngeal squamous cell carcinoma

Autor: Samuel B, Pattle, Natasa, Utjesanovic, Athena, Togo, Lucy, Wells, Brendan, Conn, Hannah, Monaghan, Elizabeth, Junor, Ingolfur, Johannessen, Kate, Cuschieri, Simon, Talbot

Publikováno v: Genes, chromosomescancer. 56(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6e3e561ef4e5565b536c20f1a4d42c70
https://pubmed.ncbi.nlm.nih.gov/27750372

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The role of Epstein–Barr virus in cancer

Autor: Paul J. Farrell, Samuel B Pattle

Publikováno v: Expert Opinion on Biological Therapy. 6:1193-1205

Epstein-Barr virus (EBV), discovered > 40 years ago from a Burkitt's lymphoma biopsy, was the first virus to be directly associated with human cancer. EBV has two distinct life cycles in the human host; a lytic form of infection that produces new inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4b05a6a268627f98d47aeeeb6831e8
https://doi.org/10.1517/14712598.6.11.1193

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Akademický článek

pTDP‐43 aggregates accumulate in non‐central nervous system tissues prior to symptom onset in amyotrophic lateral sclerosis: a case series linking archival surgical biopsies with clinical phenotypic data

Autor: Samuel B Pattle, Judi O'Shaughnessy, Owen Kantelberg, Olivia M Rifai, Judith Pate, Kristine Nellany, Nadine Hays, Mark J Arends, Mathew H Horrocks, Fergal M Waldron, Jenna M Gregory

Publikováno v: The Journal of Pathology: Clinical Research, Vol 9, Iss 1, Pp 44-55 (2023)

Abstract Neurodegenerative diseases such as Parkinson's disease (PD), Alzheimer's disease (AD), and amyotrophic lateral sclerosis (ALS) are traditionally considered strictly neurological disorders. However, clinical presentation is not restricted to

Externí odkaz: https://doaj.org/article/c5efc50753334660a96f553350f6b2fe

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