Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Samuel B. Kombian"'
Autor:
Patrick Amoateng, Thomas A. Tagoe, Thomas K. Karikari, Kennedy K. E Kukuia, Dorcas Osei-Safo, Eric Woode, Bruno G. Frenguelli, Samuel B. Kombian
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Extracts of the tropical Cinderella plant Synedrella nodiflora are used traditionally to manage convulsive conditions in the West African sub-region. This study sought to determine the neuronal basis of the effectiveness of these plant extracts to su
Externí odkaz:
https://doaj.org/article/83e0485deae346c9a75dda3606a908ec
Autor:
Patrick Amoateng, Samuel Adjei, Dorcas Osei-safo, Kennedy K. E. Kukuia, Emelia Oppong Bekoe, Thomas K. Karikari, Samuel B. Kombian
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 17, Iss 1, Pp 1-14 (2017)
Abstract Background The hydro-ethanolic whole plant extract of Synedrella nodiflora (SNE) has demonstrated anticonvulsant, sedative and analgesic effects. Preliminary studies conducted in animals, SNE significantly decreased stereotypic behaviours su
Externí odkaz:
https://doaj.org/article/876b3e6cf4fa49c59ecafdd81591957e
Publikováno v:
International Journal of Health Care Quality Assurance, 2016, Vol. 29, Issue 6, pp. 664-674.
Autor:
Dorcas Osei-Safo, Stephen Antwi, J. Asiedu-Larbi, Akua A Asiedu-Ofei, Samuel B. Kombian, Audrey S Bonsu, Kwasi Agyei Bugyei, Kennedy Ke Kukuia, Patrick Amoateng
Publikováno v:
Second Edition in 2020 of the HSI Journal Volume 1 Issue 2 Publication. 1:71-85
Background: Pain is a major symptom usually associated with most disease states. Despite the existence of many therapies, the management of pain remains unsatisfactory globally. Medicinal plants have been used since medieval times and are still being
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dafe4266d5b3915b97f6895241bc7255
https://doi.org/10.46829/hsijournal.2020.12.1.2.71-85
https://doi.org/10.46829/hsijournal.2020.12.1.2.71-85
A novel oxazolidinone derivative PH192 demonstrates anticonvulsant activity in vivo in rats and mice
Publikováno v:
European Journal of Pharmaceutical Sciences. 130:21-26
The pharmacotherapeutic management of seizure disorders with currently available medications is not optimal due to side effects and failure of some patients to respond to all available medications. As such there is the need to develop new antiseizure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c230820b0c7dd27124d77d5439341e
https://doi.org/10.1016/j.ejps.2019.01.011
https://doi.org/10.1016/j.ejps.2019.01.011
Autor:
Thomas K. Karikari, Bruno G. Frenguelli, Thomas Tagoe, Dorcas Osei-Safo, Kennedy Kwami Edem Kukuia, Eric Woode, Samuel B. Kombian, Patrick Amoateng
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
Extracts of the tropical Cinderella plantSynedrella nodifloraare used traditionally to manage convulsive conditions in the West African sub-region. This study sought to determine the neuronal basis of the effectiveness of these plant extracts to supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27afce906374eda9c48daedd5387392
https://www.frontiersin.org/articles/10.3389/fphar.2021.610025/full
https://www.frontiersin.org/articles/10.3389/fphar.2021.610025/full
Publikováno v:
Dental Traumatology. 32:502-506
Background/Aim Soft tissue injuries have been reported as being sutured using only topical anesthesia applied in the laceration wound. The objective of this study was to assess the pharmacokinetic profile of components of Oraqix® (2.5% prilocaine an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbf01638cfe7139ab67e2c204a5f998b
https://doi.org/10.1111/edt.12294
https://doi.org/10.1111/edt.12294
Autor:
Mohamed G. Qaddoumi, Kethireddy V.V. Ananthalakshmi, Ivan O. Edafiogho, Oludotun A. Phillips, Samuel B. Kombian
Publikováno v:
European Journal of Medicinal Chemistry. 76:20-30
Due to the excellent anticonvulsant activity of previously synthesized halogenated enaminones, more disubstituted analogs were synthesized and evaluated in vitro. The new enaminones either had no effect, depressed, or enhanced population spike (PS) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3014e1e8818b513ef925875180530b
https://doi.org/10.1016/j.ejmech.2014.02.002
https://doi.org/10.1016/j.ejmech.2014.02.002
Publikováno v:
Medical Principles and Practice
Objective: To test the hypothesis that a triazolyloxazolidinone (PH084) has anticonvulsant activity by examining its effects on in vitro seizure models in the rat hippocampus. Materials and Methods: Whole-cell synaptic currents, action potentials and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5595af24aab57707737fc2fd8a982f1
https://doi.org/10.1159/000346005
https://doi.org/10.1159/000346005
Publikováno v:
International Journal of Clinical Pharmacy. 35:57-64
Background The metabolic syndrome is a cluster of cardiovascular risk factors and its prevalence is alarmingly high in Kuwait, affecting nearly one third of the adult population. There is lack of information about the role of community pharmacists in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b901e4905876d16ad9fa471a4cd16be0
https://doi.org/10.1007/s11096-012-9705-4
https://doi.org/10.1007/s11096-012-9705-4