Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Samuel B. Burnim"'
Autor:
Ye Sun, Raffael Liegl, Yan Gong, Anima Bühler, Bertan Cakir, Steven S. Meng, Samuel B. Burnim, Chi-Hsiu Liu, Tristan Reuer, Peipei Zhang, Johanna M. Walz, Franziska Ludwig, Clemens Lange, Hansjürgen Agostini, Daniel Böhringer, Günther Schlunck, Lois E.H. Smith, Andreas Stahl
Publikováno v:
EBioMedicine, Vol 18, Iss C, Pp 281-287 (2017)
Pathological neovascularization of the outer retina is the hallmark of neovascular age-related macular degeneration (nAMD). Building on our previous observations that semaphorin 3F (Sema3f) is expressed in the outer retina and demonstrates anti-angio
Externí odkaz:
https://doaj.org/article/c1aaf2f7dbd947aab178877a2b28334f
Autor:
Zhongjie Fu, Yan Gong, Raffael Liegl, Zhongxiao Wang, Chi-Hsiu Liu, Steven S. Meng, Samuel B. Burnim, Nicholas J. Saba, Thomas W. Fredrick, Peyton C. Morss, Ann Hellstrom, Saswata Talukdar, Lois E.H. Smith
Publikováno v:
Cell Reports, Vol 18, Iss 7, Pp 1606-1613 (2017)
Pathological neovascularization, a leading cause of blindness, is seen in retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration. Using a mouse model of hypoxia-driven retinal neovascularization, we find that fibroblas
Externí odkaz:
https://doaj.org/article/7bbc0fb921d94e9aabe7c74528ed6f95
Autor:
Yan Gong, Zhuo Shao, Zhongjie Fu, Matthew L. Edin, Ye Sun, Raffael G. Liegl, Zhongxiao Wang, Chi-Hsiu Liu, Samuel B. Burnim, Steven S. Meng, Fred B. Lih, John Paul SanGiovanni, Darryl C. Zeldin, Ann Hellström, Lois E.H. Smith
Publikováno v:
EBioMedicine, Vol 13, Iss C, Pp 201-211 (2016)
Neovascular eye diseases including retinopathy of prematurity, diabetic retinopathy and age-related-macular-degeneration are major causes of blindness. Fenofibrate treatment in type 2 diabetes patients reduces progression of diabetic retinopathy inde
Externí odkaz:
https://doaj.org/article/9ac54728e7dc4d9d8242e2c51cca0289
Autor:
Zhongjie Fu, Chatarina A Löfqvist, Raffael Liegl, Zhongxiao Wang, Ye Sun, Yan Gong, Chi‐Hsiu Liu, Steven S Meng, Samuel B Burnim, Ivana Arellano, My T Chouinard, Rubi Duran, Alexander Poblete, Steve S Cho, James D Akula, Michael Kinter, David Ley, Ingrid Hansen Pupp, Saswata Talukdar, Ann Hellström, Lois EH Smith
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 1, Pp 76-90 (2018)
Abstract The neural cells and factors determining normal vascular growth are not well defined even though vision‐threatening neovessel growth, a major cause of blindness in retinopathy of prematurity (ROP) (and diabetic retinopathy), is driven by d
Externí odkaz:
https://doaj.org/article/1536fd7d6bb54cb8898d0fe56c523709
Autor:
Chi-Hsiu Liu, Alexander Poblete, Steven S. Meng, Lois E.H. Smith, Saswata Talukdar, Raffael Liegl, Yan Gong, Zhongxiao Wang, Ye Sun, Rubi Duran, Zhongjie Fu, Samuel B. Burnim, Bertan Cakir, Steve S Cho, Ivana Arellano, Ann Hellström, James D Akula, Elizabeth P Moran
Publikováno v:
Diabetes. 67:974-985
Retinal neuronal abnormalities occur before vascular changes in diabetic retinopathy. Accumulating experimental evidence suggests that neurons control vascular pathology in diabetic and other neovascular retinal diseases. Therefore, normalizing neuro
Autor:
Chi-Hsiu Liu, Michael Kinter, Raffael Liegl, Steven S. Meng, My T. Chouinard, Steve S Cho, James D Akula, David Ley, Ye Sun, Saswata Talukdar, Lois E.H. Smith, Zhongxiao Wang, Yan Gong, Chatarina Löfqvist, Ann Hellström, Ivana Arellano, Alexander Poblete, Rubi Duran, Ingrid Hansen Pupp, Zhongjie Fu, Samuel B. Burnim
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 10, Iss 1, Pp 76-90 (2018)
EMBO Molecular Medicine, Vol 10, Iss 1, Pp 76-90 (2018)
The neural cells and factors determining normal vascular growth are not well defined even though vision‐threatening neovessel growth, a major cause of blindness in retinopathy of prematurity (ROP) (and diabetic retinopathy), is driven by delayed no
Autor:
William T. Pu, Thomas Fredrick, Yan Gong, Raffael Liegl, James D. Akula, Ye Sun, Steven S. Meng, Lois E.H. Smith, Zhiqiang Lin, Zhongxiao Wang, Jing Chen, Samuel B. Burnim, Chi-Hsiu Liu
Publikováno v:
The Journal of Experimental Medicine
Pathological neovessels growing into the normally avascular photoreceptors cause vision loss in many eye diseases. Sun et al. find that a master inflammatory regulator, c-Fos, in photoreceptor controls retinal blood vessel growth into the photorecept
Publikováno v:
Clinical & Experimental Ophthalmology. 45:529-538
Background Retinopathy of prematurity is one of the leading causes of childhood blindness worldwide, with vessel growth cessation and vessel loss in phase I followed by neovascularization in phase II. Ischemia contributes to its pathogenesis and lute
Autor:
Matthew L. Edin, Kin Sing Stephen Lee, John Paul SanGiovanni, Zhongxiao Wang, Darryl C. Zeldin, Elizabeth P Moran, Nicholas Saba, Ann Hellström, Chi-Hsiu Liu, Thomas Fredrick, Bruce D. Hammock, Steven Meng, Fred B. Lih, Zhongjie Fu, Peyton Morss, Samuel B. Burnim, Yan Gong, Zhuo Shao, Lois E.H. Smith
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology, vol 36, iss 9
Objective— Pathological ocular neovascularization is a major cause of blindness. Increased dietary intake of ω-3 long-chain polyunsaturated fatty acids (LCPUFA) reduces retinal neovascularization and choroidal neovascularization (CNV), but ω-3 LC
Autor:
Steven S. Meng, Jing Chen, Laura A. Solt, Samuel B. Burnim, Ye Sun, John Paul SanGiovanni, Chi-Hsiu Liu, Theodore M. Kamenecka, Zhongxiao Wang
Pathological proliferation of retinal blood vessels commonly causes vision impairment in proliferative retinopathies, including retinopathy of prematurity. Dysregulated crosstalk between the vasculature and retinal neurons is increasingly recognized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e95c527b40c363f88d520861ed36e0cf
https://europepmc.org/articles/PMC5602899/
https://europepmc.org/articles/PMC5602899/