Výsledky vyhledávání - "Samuel B Reynolds"

Akademický článek

mTORC1-S6K activation by endotoxin contributes to cytokine up-regulation and early lethality in animals.

Autor: Po-Shun Lee, Anna S K Wilhelmson, Anton P Hubner, Samuel B Reynolds, Dana A Gallacchi, Terry T Chiou, David J Kwiatkowski

Publikováno v: PLoS ONE, Vol 5, Iss 12, p e14399 (2010)

mTORC1 (mammalian target of rapamycin complex 1) activation has been demonstrated in response to endotoxin challenge, but the mechanism and significance are unclear. We investigated the effect of mTORC1 suppression in an animal model of endotoxemia a

Externí odkaz: https://doaj.org/article/a9c7fa2bab1b4ab7816a3510db84f54a

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How healthcare providers find information regarding benefits and harms of treatments at an independent academic center: a cross-sectional study (Preprint)

Autor: Rahul Mhaskar, Bryan Kane, Jordan Davies, Angela Davis, Maria Karagias, Matthew Molnar, Robert Postlethwaite, Brittany Quinn, Samuel B. Reynolds, Monica Stewart, Nicholas Werbeckes, Robert Barraco

BACKGROUND The information-seeking behavior of physicians to cater to the patient's information needs is not comprehensively studied. OBJECTIVE Our cross-sectional study's key goals were to understand providers' information-seeking behavior regarding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22656c17fac9019a373bfc1696acddef
https://doi.org/10.2196/preprints.48180

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New approaches to tackle cytopenic myelofibrosis

Autor: Samuel B. Reynolds, Kristen Pettit

Publikováno v: Hematology Am Soc Hematol Educ Program

Myelofibrosis (MF) is a clonal hematopoietic stem cell neoplasm characterized by constitutional symptoms, splenomegaly, and risks of marrow failure or leukemic transformation and is universally driven by Jak/STAT pathway activation. Despite sharing t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f494baf7cf3ee72ebc3e8424fb2442e5
https://pubmed.ncbi.nlm.nih.gov/36485113

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Hereditary leiomyomatosis and renal cell cancer presenting as urothelial carcinoma

Autor: Quang L Nguyen, Samuel B Reynolds, Rishi Charate, Padmini Moffett

Publikováno v: Journal of Onco-Nephrology. 5:178-182

Hereditary leiomyomatosis is a genetic disorder that follows an autosomal dominant pattern of inheritance. Along with a variety of leiomyomas, affected individuals are predisposed to developing an aggressive form of type 2 papillary renal malignancy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cb70eb0e1404da3b204fd8fb0d5b1ec5
https://doi.org/10.1177/23993693211041370

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Head and Neck Cancer

Autor: Irene Tsung, Samuel B. Reynolds, Paul L. Swiecicki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8c74113c90b9448fbb449b0321b66ca
https://doi.org/10.1891/9780826145987.0001

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Abstract 4537: Erdheim Chester disease: A retrospective study characterizing the molecular and pathologic footprints with clinical presentation and comparative outcomes in the present era of targeted molecular targeted therapy

Autor: Sabrina R. Wilcox, Samuel B. Reynolds, Jennifer Girard, Asra Ahmed

Publikováno v: Cancer Research. 83:4537-4537

Erdheim Chester Disease (ECD) is a rare, non-Langerhans cell histiocytic disease, characterized as a neoplastic disorder in 2016. MAP Kinase and PI3-AKT pathway somatic mutations and/or fusion genes have been shown to play a significant role in disea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::786bb93173a8291e2f6cae563b4f5280
https://doi.org/10.1158/1538-7445.am2023-4537

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Abstract 4536: Investigating the correlation between molecular diagnostics, targeted therapies and treatment outcomes in Rosai Dorfman disease: a single-institution experience

Autor: Samuel B. Reynolds, Sabrina R. Wilcox, Moshe Talpaz, Asra Z. Ahmed

Publikováno v: Cancer Research. 83:4536-4536

Introduction: Rosai Dorfman Disease (RDD) is a non-Langerhans cell histiocytic disease whose pathologic features include sinus histiocytosis with variable emperipolesis. Traditional management consists of local therapies (resection, radiation) for li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8fff99a442b6e51628b1d000ddf9a6df
https://doi.org/10.1158/1538-7445.am2023-4536

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Fat Embolism Syndrome With Cerebral Involvement: An Underrecognized Complication of Long Bone Fractures

Autor: Quang L Nguyen, Benadin Varajic, Samuel B Reynolds, Karim El-Kersh

Publikováno v: Cureus.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d03cd42d08f65dc13ff62cdee2890038
https://doi.org/10.7759/cureus.22816

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Increased infection rates associated with second-generation antipsychotics

Autor: Samuel B Reynolds, Taelor T. Lee, Rif S. El-Mallakh, Megan E. Durham, Daniel Stephen Demick

Publikováno v: Annals of Clinical Psychiatry. 33:53-55

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1625468236061c2bb15a2635c979b97b
https://doi.org/10.12788/acp.0017

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The First Case of Ignatzschineria ureiclastica/larvae in the United States Presenting as a Myiatic Wound Infection

Autor: Samuel B Reynolds, Clayton Smith, Kasey Reed

Publikováno v: Cureus

Ignatzschineria is a recently identified genus of bacteria that has been isolated from the digestive tract of multiple flies associated with decomposing tissue. Species within this genus are rarely implicated in human disease, and less than 10 cases

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9757460ee4e1c17575d165367fe84e71
http://europepmc.org/articles/PMC8126268

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