Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Samuel B Barone"'
Autor:
Arshad M. Khanani, MD, MA, Raj K. Maturi, MD, Nika Bagheri, MD, Benjamin Bakall, MD, PhD, David S. Boyer, MD, Stephen S. Couvillion, MD, Dilsher S. Dhoot, MD, Nancy M. Holekamp, MD, Karim N. Jamal, MD, Dennis M. Marcus, MD, Dante Pieramici, MD, Aamir A. Aziz, BS, Kiran C. Patki, MD, William Z. Bridges, Jr., MD, Samuel B. Barone, MD
Publikováno v:
Ophthalmology Science, Vol 2, Iss 2, Pp 100154- (2022)
Purpose: To establish the safety, tolerability, pharmacokinetics, and pharmacodynamics of an intravitreal injection of recombinant human complement factor H (CFH), GEM103, in individuals with genetically defined age-related macular degeneration (AMD)
Externí odkaz:
https://doaj.org/article/007c8c367e964d47b7fc962c7e0acaa8
Autor:
Aaron L. Magno, Martyn A. French, Ian J. Constable, Samuel B. Barone, Elizabeth Rakoczy, Mark S. Blumenkranz, Steven D. Schwartz, Mariapia A. Degli-Esposti, Chooi May Lai
Publikováno v:
American Journal of Ophthalmology. 177:150-158
Purpose To assess the safety of rAAV.sFlt-1 subretinal injection in neovascular age-related macular degeneration (wet AMD) over 36 months. Design Phase 1 dose escalation trial. Methods Eight subjects with advanced, treatment-experienced wet AMD were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21dc6c4982f9911b030ce4678eefea5f
https://doi.org/10.1016/j.ajo.2017.02.018
https://doi.org/10.1016/j.ajo.2017.02.018
Publikováno v:
Cutaneous and ocular toxicology. 38(3)
Purpose: To determine the ocular and systemic toxicity of a novel, topically applied ophthalmic gel preparation of povidone-iodine (PVP-I) and dimethylsulfoxide (DMSO) in Dutch-Belted rabbits.Mater...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08dcf29f99087637312fa12b901f1bc3
https://pubmed.ncbi.nlm.nih.gov/30741035
https://pubmed.ncbi.nlm.nih.gov/30741035
Autor:
Mariapia A. Degli-Esposti, Cora M. Pierce, Steven D. Schwartz, Aaron L. Magno, Mark S. Blumenkranz, Elizabeth Rakoczy, Ian L. McAllister, Martyn A. French, Samuel B. Barone, Steve Butler, Ian J. Constable, Chooi May Lai
Publikováno v:
EBioMedicine
Background We present the results of a Phase 2a randomized controlled trial investigating the safety, and secondary endpoints of subretinal rAAV.sFLT-1 gene therapy in patients with active wet age-related macular degeneration (wAMD). Methods All pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e74d93408b8920a61cdfec926883c2e3
Autor:
Chris Worrall, Richard A. Forshee, Hector S. Izurieta, Samuel B Barone, Craig E. Zinderman, Thomas E. MaCurdy, Jeffrey A. Kelman, Austin Wagoner, Dongyi Tony Du
Publikováno v:
Ophthalmology. 121:290-298
Objective To estimate the incidence of infectious endophthalmitis after corneal transplant or cataract surgery, to evaluate the trend of endophthalmitis during the study period, and to assess demographic risk factors for endophthalmitis after surgeri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88fbef111265af70b53d6e555697f315
https://doi.org/10.1016/j.ophtha.2013.07.016
https://doi.org/10.1016/j.ophtha.2013.07.016
Autor:
Chooi-May Lai, Aaron L. Magno, Steven D. Schwartz, Martyn A. French, Mariapia A. Degli-Esposti, Mark S. Blumenkranz, Ian J. Constable, Elizabeth P. Rakoczy, Samuel B. Barone
Publikováno v:
Molecular Therapy. 24:S97-S98
Purpose: To assess safety following subretinal rAAV.sFlt-1 injection at one year. Secondary endpoints were assessed for evidence of biologic activity. Methods: Under the protocol, Phase 1 followed a dose escalation design where eligible subjects rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::972ce1f11c141e5e6c7fcca9ab87a8a8
https://doi.org/10.1016/s1525-0016(16)33057-x
https://doi.org/10.1016/s1525-0016(16)33057-x