Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Samuel A. Woodle"'
Publikováno v:
Thrombosis Journal, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Fluorogenic thrombin generation (TG) is a global hemostasis assay that provides an overall representation of hemostasis potential. However, the accurate detection of thrombin activity in plasma may be affected by artifacts inheren
Externí odkaz:
https://doaj.org/article/a8aca791941b4f26874d39baf9ca8f78
Autor:
Yideng Liang, Joseph W. Jackson, Samuel A. Woodle, Stepan S. Surov, Leonid A. Parunov, Dorothy E. Scott, Mark Weinstein, Timothy K. Lee, Mikhail V. Ovanesov
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 1, Pp 211-222 (2021)
Abstract Background Activated coagulation factor XIa (FXIa) is an impurity and primary source of procoagulant activity in thrombosis‐implicated immune globulin (IG) products. Several assays, of varying quality and precision are used to assess FXIa
Externí odkaz:
https://doaj.org/article/ab2eec995bec476b91c3b022656c3222
Autor:
Tseday Z. Tegegn, Silvia H. De Paoli, Martina Orecna, Oumsalama K. Elhelu, Samuel A. Woodle, Ivan D. Tarandovskiy, Mikhail V. Ovanesov, Jan Simak
Publikováno v:
Journal of Extracellular Vesicles, Vol 5, Iss 0, Pp 1-13 (2016)
Background: Freezing is promising for extended platelet (PLT) storage for transfusion. 6% DMSO cryopreserved PLTs (CPPs) are currently in clinical development. CPPs contain significant amount of platelet membrane vesicles (PMVs). PLT-membrane changes
Externí odkaz:
https://doaj.org/article/d89077311f6b44bbbc16ca10675930b4
Autor:
Joseph W Jackson, M J Weinstein, Dorothy E. Scott, Mikhail V Ovanesov, Leonid A. Parunov, Samuel A. Woodle, Timothy K Lee, Yideng Liang, Stepan S Surov
Publikováno v:
Research and Practice in Thrombosis and Haemostasis
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 1, Pp 211-222 (2021)
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 1, Pp 211-222 (2021)
Background Activated coagulation factor XIa (FXIa) is an impurity and primary source of procoagulant activity in thrombosis‐implicated immune globulin (IG) products. Several assays, of varying quality and precision are used to assess FXIa‐like pr
Publikováno v:
Journal of Thrombosis and Haemostasis. 12:1302-1312
Summary Background Recombinant factor VIIa (rFVIIa) is an FX-cleaving coagulation enzyme licensed for the treatment of bleeding episodes in hemophiliacs with inhibitory antibodies. Even though the optimal dosing and comparative dose efficacy of rFVII
Publikováno v:
Thrombosis Research. 132:374-380
Background Despite increasing recognition as a more precise test of in vivo hemostatic conditions, standardization of the thrombin generation test (TGT) continues to hinder its development as routine clinical practice. Prior efforts largely focused o
Autor:
N. K. Jha, Yideng Liang, M. J. Gourley, Mikhail V Ovanesov, Svetlana A Shestopal, Andrey G Sarafanov, Samuel A. Woodle, Milton C. Weinstein
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 22(5)
Introduction The thrombin generation test (TGT) is used both as a global haemostasis assay, and to compare activities of coagulation factor concentrates that have been spiked into patient plasma. However, TGT has not been systematically optimized to
Autor:
Samuel A. Woodle, Svetlana A Shestopal, Andrey G Sarafanov, Mikhail V Ovanesov, Timothy K Lee, James H. Kurasawa
Publikováno v:
Biochemistry. 54(2)
Low-density lipoprotein receptor-related protein 1 (LRP) mediates clearance of blood coagulation factor VIII (FVIII). In LRP, FVIII binds the complement-type repeats (CRs) of clusters II and IV, which also bind a majority of other LRP ligands. No lig
Autor:
Mikhail V Ovanesov, Jan Simak, Tseday Z. Tegegn, Martina Orecna, Silvia H. De Paoli, Ivan D. Tarandovskiy, Samuel A. Woodle, Oumsalama K. Elhelu
Publikováno v:
Journal of Extracellular Vesicles; Vol 5 (2016) incl supplements
Journal of Extracellular Vesicles
Journal of Extracellular Vesicles, Vol 5, Iss 0, Pp 1-13 (2016)
Journal of Extracellular Vesicles
Journal of Extracellular Vesicles, Vol 5, Iss 0, Pp 1-13 (2016)
Background : Freezing is promising for extended platelet (PLT) storage for transfusion. 6% DMSO cryopreserved PLTs (CPPs) are currently in clinical development. CPPs contain significant amount of platelet membrane vesicles (PMVs). PLT-membrane change
Recombinant factor VIIa (rFVIIa) is used for treatment of hemophilia patients with inhibitors, as well for off-label treatment of severe bleeding in trauma and surgery. Effective bleeding control requires supraphysiological doses of rFVIIa, posing bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72bc0b393eb38552f023b630501cee8
https://europepmc.org/articles/PMC3412350/
https://europepmc.org/articles/PMC3412350/