Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Samuel A. Sakhai"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
The tyrosine kinase Fyn plays an important role in synaptic plasticity, learning, and memory. Here we report that Fyn is activated in response to 15 min D1 receptor (D1R) but not D2 receptor (D2R) stimulation specifically in the dorsomedial striatum
Externí odkaz:
https://doaj.org/article/afeb515710114fa68d72558c688d1950
Publikováno v:
Psychopharmacology. 240:303-317
Background The brain-derived neurotrophic factor (BDNF) Valine 66 to Methionine human polymorphism results in impaired activity-dependent BDNF release and has been linked to psychiatric disorders including depression and anxiety. We previously showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05404aa3e8c36ebab5a0a0f2cb39ca1
https://doi.org/10.1007/s00213-022-06305-3
https://doi.org/10.1007/s00213-022-06305-3
Publikováno v:
Psychopharmacology.
The brain-derived neurotrophic factor (BDNF) Valine 66 to Methionine human polymorphism results in impaired activity-dependent BDNF release and has been linked to psychiatric disorders including depression and anxiety. We previously showed that male
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::26657f3c5b5136e385997200d8aeab4d
https://pubmed.ncbi.nlm.nih.gov/36622381
https://pubmed.ncbi.nlm.nih.gov/36622381
Brain-derived neurotrophic factor (BDNF) signaling in the dorsolateral striatum (DLS) gates alcohol self-administration in rodents. The major source of BDNF in the striatum is the cortex, and we recently found that BDNF-expressing neurons in the vent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a78a94f80f6d25566148afe005e20aa
https://doi.org/10.1101/2021.09.10.459813
https://doi.org/10.1101/2021.09.10.459813
Autor:
Yann Ehinger, Dorit Ron, Drishti Soneja, Samuel A. Sakhai, Martin F. Adrover, Khanhky Phamluong, Veronica A. Alvarez, Nadege Morisot
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Neuropsychopharmacology
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Neuropsychopharmacology
Fyn kinase in the dorsomedial striatum (DMS) of rodents plays a central role in mechanisms underlying excessive alcohol intake. The DMS is comprised of medium spiny neurons (MSNs) that project directly (dMSNs) or indirectly (iMSNs) to the substantia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de988d490b4e7a370583f395c77c0afa
http://www.nature.com/articles/s41386-020-0712-1
http://www.nature.com/articles/s41386-020-0712-1
Autor:
David Darevesky, Ellanor L. Whiteley, Sophie Laguesse, Dorit Ron, Anthony L. Berger, Yann Ehinger, Marie Lordkipanidzé, Khanhky Phamluong, Samuel A. Sakhai, Jeffrey J. Moffat, Mélanie Welman, Mehdi Farokhnia, Lorenzo Leggio
Publikováno v:
Addict Biol
Heavy alcohol use reduces the levels of the brain-derived neurotrophic factor (BDNF) in the prefrontal cortex of rodents through the upregulation of microRNAs (miRs) targeting BDNF mRNA. In humans, an inverse correlation exists between circulating bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4a540c64d9d0d78cad1498d41f25ab
https://doi.org/10.1111/adb.12890
https://doi.org/10.1111/adb.12890
Autor:
Anthony L. Berger, Sophie Laguesse, Mélanie Welman, Samuel A. Sakhai, Marie Lordkipanidzé, Mehdi Farokhnia, Dorit Ron, Ellanor L. Whiteley, Khanhky Phamluong, Lorenzo Leggio, Jeffrey J. Moffat, David Darevesky, Yann Ehinger
Heavy alcohol use reduces the levels of the brain-derived neurotrophic factor (BDNF) in the prefrontal cortex of rodents through the upregulation of microRNAs targetingBDNFmRNA. In humans, an inverse correlation exists between circulating blood level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611aab1fe7ea9c3bf1b0a5381192e4d4
https://doi.org/10.1101/2019.12.18.881680
https://doi.org/10.1101/2019.12.18.881680
Autor:
Daniel T Blumstein, Luis Ebensperger, Loren Hayes, Rodrigo A Vásquez, Todd H Ahern, Joseph R Burger, Adam G Dolezal, Andy Dosmann, Gabriela G Mariscal, Breanna N Harris, Emilio A Herrera, Eileen A Lacey, Jill Mateo, Lisa McGraw, Daniel Olazábal, Marilyn Ramenofsky, Dustin R Rubenstein, Samuel A Sakhai, Wendy Saltzman, Cristina Sainz-Borgo, Mauricio Soto-Gamboa, Monica L Stewart, Tina W Wey, John C Wingfield, Larry J Young
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 4 (2010)
Social interactions among conspecifics are a fundamental and adaptively significant component of the biology of numerous species. Such interactions give rise to group living as well as many of the complex forms of cooperation and conflict that occur
Externí odkaz:
https://doaj.org/article/9149d88faba946ea93aec5eeedb3f706
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, vol 43, iss 7
Actin is highly enriched at dendritic spines, and actin remodeling plays an essential role in structural plasticity. The mammalian target of rapamycin complex 2 (mTORC2) is a regulator of actin polymerization. Here, we report that alcohol consumption
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d714cfcbba77dac4d6d9a0d369387ac5
https://europepmc.org/articles/PMC5983552/
https://europepmc.org/articles/PMC5983552/
Publikováno v:
Developmental Psychobiology. 58:39-51
Stress influences a wide variety of outcomes including cognitive processing. In the rat, early life maternal care can influence developing offspring to affect both stress reactivity and cognitive processes in adulthood. The current study assessed if
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e8c344f7f930f0b7a86b5101b0df5ba
https://doi.org/10.1002/dev.21343
https://doi.org/10.1002/dev.21343