Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Samuel A. LoCascio"'
Publikováno v:
eLife, Vol 8 (2019)
Patterns of synaptic connectivity are remarkably precise and complex. Single-cell RNA sequencing has revealed a vast transcriptional diversity of neurons. Nevertheless, a clear logic underlying the transcriptional control of neuronal connectivity has
Externí odkaz:
https://doaj.org/article/5cd572eb41104dc7b244e48193ecd17b
Autor:
Juyoun Yoo, Mark Dombrovski, Parmis Mirshahidi, Aljoscha Nern, Samuel A. LoCascio, S. Lawrence Zipursky, Yerbol Z. Kurmangaliyev
SummaryHow do developing neurons select their synaptic partners? To identify molecules matching synaptic partners, we integrated the synapse-level connectome of neural circuits with the developmental expression patterns and binding specificities of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f9a6363268d50ad9b994786e1968ac1
https://doi.org/10.1101/2023.04.03.534791
https://doi.org/10.1101/2023.04.03.534791
Autor:
Saumya Jain, Parmis Mirshahidi, Ying Lin, Yerbol Z. Kurmangaliyev, S. Lawrence Zipursky, Samuel A. LoCascio, Javier Valdes-Aleman, Brianna Parrington
The assembly of neural circuits is dependent upon precise spatiotemporal expression of cell recognition molecules1–6. Factors controlling cell-type specificity have been identified7–9, but how timing is determined remains unknown. Here we describ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54e58bc6d6c0d6972485a43e86837ff0
https://doi.org/10.1101/2020.09.18.304410
https://doi.org/10.1101/2020.09.18.304410
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
Patterns of synaptic connectivity are remarkably precise and complex. Single-cell RNA sequencing has revealed a vast transcriptional diversity of neurons. Nevertheless, a clear logic underlying the transcriptional control of neuronal connectivity has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48fda76579266609d313a2aee793a70
https://elifesciences.org/articles/50822
https://elifesciences.org/articles/50822
Publikováno v:
Science (New York, N.Y.). 360(6387)
A recipe for regeneration Unlike humans, planarian flatworms can regenerate certain tissues. During regeneration, existing tissues remodel, and undifferentiated and progenitor cells convert into specialized cell types at specified locations. Atabay e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a7121954f0a47bc31e1afce85f7ce3
https://pubmed.ncbi.nlm.nih.gov/29700249
https://pubmed.ncbi.nlm.nih.gov/29700249
Autor:
Megan Sykes, Dario A. A. Vignali, Semir Beyaz, Carrie L. Lucas, Samuel A. LoCascio, Guiling Zhao, Creg J. Workman
Publikováno v:
Blood. 117:5532-5540
Administration of a single dose of anti-CD40L mAb at the time of allogeneic BM transplantation tolerizes peripheral alloreactive T cells and permits establishment of mixed hematopoietic chimerism in mice. Once engrafted, mixed chimeras are systemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00229067cebec4f248d54b4e17d97ed9
https://doi.org/10.1182/blood-2010-11-318675
https://doi.org/10.1182/blood-2010-11-318675
Publikováno v:
Current Stem Cell Research & Therapy. 6:29-37
Type 1 diabetes (T1D) is an autoimmune disease that leads to the destruction of the insulin-producing pancreatic b cells. While there is no current cure, recent work in the field of allogeneic hematopoietic stem cell transplantation (HSCT) and the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c541222d75eaf2c58900f211be2f137c
https://doi.org/10.2174/157488811794480681
https://doi.org/10.2174/157488811794480681
Tracking donor-reactive T cells: Evidence for clonal deletion in tolerant kidney transplant patients
Autor:
Heather Morris, Suxiao Yang, Megan Sykes, Susan DeWolf, Harlan Robins, Waichi Wong, Julien Zuber, Tatsuo Kawai, Brittany Shonts, Samuel A. LoCascio, Yufeng Shen, Ben Sprangers
Publikováno v:
Science Translational Medicine. 7
T cell responses to allogeneic major histocompatibility complex antigens present a formidable barrier to organ transplantation, necessitating long-term immunosuppression to minimize rejection. Chronic rejection and drug-induced morbidities are major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bcd054492c4af5bad1e67e839ecfa48
https://doi.org/10.1126/scitranslmed.3010760
https://doi.org/10.1126/scitranslmed.3010760
Publikováno v:
PMC
Dividing cells called neoblasts contain pluripotent stem cells and drive planarian flatworm regeneration from diverse injuries. A long-standing question is whether neoblasts directly sense and respond to the identity of missing tissues during regener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0298c9e7ed955c687300e27e503b172
https://doi.org/10.1016/j.devcel.2017.02.002
https://doi.org/10.1016/j.devcel.2017.02.002