Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Samuel A Ramirez"'
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 7, p e1008525 (2021)
Cells polarize their movement or growth toward external directional cues in many different contexts. For example, budding yeast cells grow toward potential mating partners in response to pheromone gradients. Directed growth is controlled by polarity
Externí odkaz:
https://doaj.org/article/838e930338424d3a95882d04a4663ebc
Autor:
Jian-Geng Chiou, Samuel A Ramirez, Timothy C Elston, Thomas P Witelski, David G Schaeffer, Daniel J Lew
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 4, p e1006095 (2018)
Rho-GTPases are master regulators of polarity establishment and cell morphology. Positive feedback enables concentration of Rho-GTPases into clusters at the cell cortex, from where they regulate the cytoskeleton. Different cell types reproducibly gen
Externí odkaz:
https://doaj.org/article/8e433b07af2e47d8862921258e600ded
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 3, p e1006016 (2018)
Polarity establishment, the spontaneous generation of asymmetric molecular distributions, is a crucial component of many cellular functions. Saccharomyces cerevisiae (yeast) undergoes directed growth during budding and mating, and is an ideal model o
Externí odkaz:
https://doaj.org/article/24542db809e4434ea8b075a9d16a6aa7
Publikováno v:
IEEE/ASME Transactions on Mechatronics. 27:1829-1836
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54a44d78539139a2734c2fa153b5ec07
https://doi.org/10.1109/tmech.2022.3175507
https://doi.org/10.1109/tmech.2022.3175507
Molecular solubility is among the key properties that determine the clinical performance of a drug candidate because poor molecular solubility often indicates inadequate bioavailability. Using the CombiSolv-Exp database, we test several models (Gauss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2626bda074c3d80590fdc6eb4c89200a
https://doi.org/10.21203/rs.3.rs-2604981/v1
https://doi.org/10.21203/rs.3.rs-2604981/v1
Publikováno v:
Proceedings of the National Academy of Sciences. 118
How small eukaryotic cells can interpret dynamic, noisy, and spatially complex chemical gradients to orient growth or movement is poorly understood. We address this question using Saccharomyces cerevisiae, where cells orient polarity up pheromone gra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3694672a541d3ebc8de112b5f3aa7051
https://doi.org/10.1073/pnas.2025445118
https://doi.org/10.1073/pnas.2025445118
Publikováno v:
Business Wire (English). 09/26/2024.
Publikováno v:
Business Wire (English). 07/30/2024.
Autor:
Chad Leidy, Samuel A. Ramirez
Publikováno v:
The journal of physical chemistry. B. 122(38)
After photoactivation, rhodopsin (R), a G-protein-coupled receptor, rapidly activates multiple transducin G-proteins (G) in an initial amplification step of phototransduction. G-protein activation requires diffusion-mediated association with an activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19160ee778a8eb7df165eafae9521fc8
https://pubmed.ncbi.nlm.nih.gov/30156842
https://pubmed.ncbi.nlm.nih.gov/30156842
Publikováno v:
Molecular Biology of the Cell
The spread of Cdc42 activation at dendritic spines is modeled by means of reaction-diffusion equations solved on spine-like geometries. Excitable behavior arising from positive feedback in Cdc42 activation leads to traveling waves of Cdc42 activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffda26ec1f672f96cd284d29a07f56b
https://doi.org/10.1091/mbc.e15-06-0405
https://doi.org/10.1091/mbc.e15-06-0405