Zobrazeno 1 - 10
of 540
pro vyhledávání: '"Samuel A, Wickline"'
Autor:
Qingyu Zhou, John C. Harding, Ping Fan, Ivan Spasojevic, Attila Kovacs, Antonina Akk, Adam Mitchell, Luke E. Springer, Joseph P. Gaut, Daniel A. Rauch, Samuel A. Wickline, Christine T. N. Pham, Katherine Fuh, Hua Pan
Publikováno v:
Nanomaterials, Vol 14, Iss 21, p 1752 (2024)
Nanomedicine holds great potential for revolutionizing medical treatment. Ongoing research and advancements in nanotechnology are continuously expanding the possibilities, promising significant advancements in healthcare. To fully harness the potenti
Externí odkaz:
https://doaj.org/article/065f548de32f4785bba0977573db983a
Autor:
Christopher Collazo, Ian Vargas, Brendon Cara, Carla J. Weinheimer, Ryan P. Grabau, Dmitry Goldgof, Lawrence Hall, Samuel A. Wickline, Hua Pan
Publikováno v:
Bioengineering, Vol 11, Iss 5, p 434 (2024)
The progress of incorporating deep learning in the field of medical image interpretation has been greatly hindered due to the tremendous cost and time associated with generating ground truth for supervised machine learning, alongside concerns about t
Externí odkaz:
https://doaj.org/article/2513b52266984b0897f60ddbe2a5e62f
Autor:
Krishnan MohanKumar, Kopperuncholan Namachivayam, Tanjing Song, Byeong Jake Cha, Andrea Slate, Jeanne E. Hendrickson, Hua Pan, Samuel A. Wickline, Joo-Yeun Oh, Rakesh P. Patel, Ling He, Benjamin A. Torres, Akhil Maheshwari
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
The development of neonatal necrotising enterocolitis has been temporally associated with red blood cell transfusions in retrospective human studies. Here, the authors develop a neonatal mouse model of necrotising enterocolitis in anaemic mice receiv
Externí odkaz:
https://doaj.org/article/6410e0e9afc14c3486229368579878f2
Autor:
Janet B. McGill, Mariko Johnson, Stacy Hurst, William T. Cade, Kevin E. Yarasheski, Richard E. Ostlund, Kenneth B. Schechtman, Babak Razani, Michael B. Kastan, Donald A. McClain, Lisa de las Fuentes, Victor G. Davila-Roman, Daniel S. Ory, Samuel A. Wickline, Clay F. Semenkovich
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 11, Iss 1, Pp 1-16 (2019)
Abstract Background Metabolic syndrome, an obesity-related condition associated with insulin resistance and low-grade inflammation, leads to diabetes, cardiovascular diseases, cancer, osteoarthritis, and other disorders. Optimal therapy is unknown. T
Externí odkaz:
https://doaj.org/article/883cd46428644f2bb3fe9700c5ff28bf
Autor:
Qingyu Zhou, Justin Doherty, Antonina Akk, Luke E. Springer, Ping Fan, Ivan Spasojevic, Ganesh V. Halade, Huanghe Yang, Christine T. N. Pham, Samuel A. Wickline, Hua Pan
Publikováno v:
Nanomaterials, Vol 12, Iss 3, p 336 (2022)
Cancer treatment-induced toxicities may restrict maximal effective dosing for treatment and cancer survivors’ quality of life. It is critical to develop novel strategies that mitigate treatment-induced toxicity without affecting the efficacy of ant
Externí odkaz:
https://doaj.org/article/dcc9257127ab4ef79e27f0f7a34e4b4c
Autor:
Huimin Yan, Xin Duan, Kelsey H. Collins, Luke E. Springer, Farshid Guilak, Samuel A. Wickline, M. Farooq Rai, Hua Pan, Christine Pham
Publikováno v:
Precision Nanomedicine, Vol 2, Iss 1 (2019)
Inflammation after joint injury leads to joint responses that result in eventual osteoarthritis development. Blockade of inflammation, by suppressing NF-κB expression, has been shown to reduce joint injury-induced chondrocyte apoptosis and reactive
Externí odkaz:
https://doaj.org/article/03f7983621f94860be58fca6f1ec1a31
Publikováno v:
Nanomaterials, Vol 11, Iss 6, p 1582 (2021)
Adult T-cell leukemia/lymphoma (ATLL) is an aggressive, clonal malignancy of mature T cells caused by human T-cell leukemia virus type 1. Although it is a rare tumor type, it serves as an excellent model of a virus driven process that transforms cell
Externí odkaz:
https://doaj.org/article/c864cf018a644cd9a7384a82a2ba1e83
Autor:
Qingyu Zhou, James D. Quirk, Ying Hu, Huimin Yan, Joseph P. Gaut, Christine T. N. Pham, Samuel A. Wickline, Hua Pan
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6086
For nearly five decades, cisplatin has played an important role as a standard chemotherapeutic agent and been prescribed to 10–20% of all cancer patients. Although nephrotoxicity associated with platinum-based agents is well recognized, treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0e2d93aad1fb91eea34b421541eee1
Autor:
Ashraf Ul Kabir, Madhav Subramanian, Jun Wu, Minseo Kim, Karen Krchma, Xiaoli Wang, Carmen M. Halabi, Hua Pan, Samuel A. Wickline, Daved H. Fremont, Kyunghee Choi
Tumor-angiogenesis and -immunity play critical roles in cancer progression and outcome. An inverse correlation of these two1hints at common regulatory mechanism(s). Here, we report thatZbtb46, a repressive transcription factor and a widely accepted m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dc2e8e1e08433dcfae209ce49d55629
https://doi.org/10.1101/2023.03.02.530835
https://doi.org/10.1101/2023.03.02.530835
Autor:
Huimin Yan, Ying Hu, Antonina Akk, Muhammad Farooq Rai, Hua Pan, Samuel A. Wickline, Christine T.N. Pham
Publikováno v:
Pharmaceutics, Vol 12, Iss 1, p 73 (2020)
Osteoarthritis (OA) is a progressive joint disease that causes significant disability and pain and for which there are limited treatment options. We posit that delivery of anabolic factors that protect and maintain cartilage homeostasis will halt or
Externí odkaz:
https://doaj.org/article/e5a2a89b381e4b91a56c78e6d42b7058