Role of efficacy as a determinant of locomotor activation by mu‐opioid receptor (MOR) ligands in female and male mice. II. Effects of novel MOR‐selective phenylmorphans with high‐to‐low MOR efficacy

Autor: Edna J. Santos, Nima Nassehi, Eric W. Bow, Dana R. Chambers, Eugene S. Gutman, Arthur E. Jacobson, Joshua A. Lutz, Samuel A. Marsh, Kenner C. Rice, Agnieszka Sulima, Dana E. Selley, S. Stevens Negus

Publikováno v: Pharmacology Research & Perspectives, Vol 11, Iss 4, Pp n/a-n/a (2023)

Abstract Low‐efficacy mu‐opioid receptor (MOR) agonists represent promising therapeutics, but existing compounds (e.g., buprenorphine, nalbuphine) span a limited range of low MOR efficacies and have poor MOR selectivity. Accordingly, new and sele

Externí odkaz: https://doaj.org/article/3416c03aeec64d3f8a90e94380e1ee04

Rate of onset of dopamine transporter inhibitors assessed with intracranial self-stimulation and in vivo dopamine photometry in rats

Autor: Tyson R. Baird, Kimberly N. Karin, Samuel A. Marsh, F. Ivy Carroll, J. M. L. Medina-Contreras, S. Stevens Negus, Jose M. Eltit

Publikováno v: Psychopharmacology. 240:969-981

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7794f6509f5162140ac7fdaf653fc7b5
https://doi.org/10.1007/s00213-023-06340-8

APOE and immunity:Research highlights

Autor: Courtney M. Kloske, Christopher J. Barnum, Andre F. Batista, Elizabeth M. Bradshaw, Adam M. Brickman, Guojun Bu, Jessica Dennison, Mary D. Gearon, Alison M. Goate, Christian Haass, Michael T. Heneka, William T. Hu, Lenique K. L. Huggins, Nahdia S. Jones, Radosveta Koldamova, Cynthia A. Lemere, Shane A. Liddelow, Edoardo Marcora, Samuel E. Marsh, Henrietta M. Nielsen, Kellen K. Petersen, Melissa Petersen, Stefanie D. Piña‐Escudero, Wei Qiao Qiu, Yakeel T. Quiroz, Eric Reiman, Claire Sexton, Malú Gámez Tansey, Julia TCW, Charlotte E. Teunissen, Betty M. Tijms, Rik van der Kant, Rebecca Wallings, Stacie C. Weninger, Whitney Wharton, Donna M. Wilcock, Tyler James Wishard, Susan L Worley, Henrik Zetterberg, Maria C. Carrillo

Publikováno v: Kloske, C M, Barnum, C J, Batista, A F, Bradshaw, E M, Brickman, A M, Bu, G, Dennison, J, Gearon, M D, Goate, A M, Haass, C, Heneka, M T, Hu, W T, Huggins, L K L, Jones, N S, Koldamova, R, Lemere, C A, Liddelow, S A, Marcora, E, Marsh, S E, Nielsen, H M, Petersen, K K, Petersen, M, Piña-Escudero, S D, Qiu, W Q, Quiroz, Y T, Reiman, E, Sexton, C, Tansey, M G M, Tcw, J, Teunissen, C E, Tijms, B M, van der Kant, R, Wallings, R, Weninger, S C, Wharton, W, Wilcock, D M, Wishard, T J, Worley, S L, Zetterberg, H & Carrillo, M C 2023, ' APOE and immunity : Research highlights ', Alzheimer's and Dementia, vol. 19, no. 6, pp. 2677-2696 . https://doi.org/10.1002/alz.13020
Alzheimer's and dementia 19(6), 2677-2696 (2023). doi:10.1002/alz.13020
Kloske, C M, Barnum, C J, Batista, A F, Bradshaw, E M, Brickman, A M, Bu, G, Dennison, J, Gearon, M D, Goate, A M, Haass, C, Heneka, M T, Hu, W T, Huggins, L K L, Jones, N S, Koldamova, R, Lemere, C A, Liddelow, S A, Marcora, E, Marsh, S E, Nielsen, H M, Petersen, K K, Petersen, M, Piña-Escudero, S D, Qiu, W Q, Quiroz, Y T, Reiman, E, Sexton, C, Tansey, M G, Tcw, J, Teunissen, C E, Tijms, B M, van der Kant, R, Wallings, R, Weninger, S C, Wharton, W, Wilcock, D M, Wishard, T J, Worley, S L, Zetterberg, H & Carrillo, M C 2023, ' APOE and immunity: Research highlights ', Alzheimer's and Dementia, vol. 19, no. 6, pp. 2677-2696 . https://doi.org/10.1002/alz.13020

INTRODUCTION: At the Alzheimer's Association's APOE and Immunity virtual conference, held in October 2021, leading neuroscience experts shared recent research advances on and inspiring insights into the various roles that both the apolipoprotein E ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d9ff92093ab0b6d772041ff569c18f
https://research.vumc.nl/en/publications/823b40ac-c075-4456-8a2d-bdf139906d29

Multi‐modal Analysis and Modeling of Human Neurodegenerative Disease to Reveal Disease Mechanisms and Biomarkers

Autor: Samuel E Marsh, Sarah Murphy, Tushar Kamath, Vahid Gazestani, Martine Therrien, Michael John Dolan, Sasa Jereb, Miguel Reyes, Johan Gobom, Clary Clish, Nir Hacohen, Henrik Zetterberg, Ville Leinonen, Evan Macosko, Beth Stevens

Publikováno v: Alzheimer's & Dementia. 18

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::946b84de0d21f1935a6bc7be72b0e768
https://doi.org/10.1002/alz.061905

Perceptions of Assessment Literacy among Current and Prospective Veterinary Students

Autor: Samuel J Marsh, Kate Cobb, Liz Mossop

Publikováno v: Journal of Veterinary Medical Education. 48:163-169

Developing assessment literacy is important for veterinary students because the demands of a veterinary medicine course require students to rapidly adapt to new ways of learning and assessment. In this study, we investigate the understanding of asses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e346afdeea410a76e396c4cc23df43f
https://doi.org/10.3138/jvme.2019-0023