Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Samuel, Amintas"'
Autor:
Samuel Amintas, Grégoire Cullot, Mehdi Boubaddi, Julie Rébillard, Laura Karembe, Béatrice Turcq, Valérie Prouzet-Mauléon, Aurélie Bedel, François Moreau-Gaudry, David Cappellen, Sandrine Dabernat
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-11 (2024)
Abstract Background The clustered regulatory interspaced short palindromic repeats (CRISPR)-Cas13a system has strong potential for highly sensitive detection of exogenous sequences. The detection of KRAS G12 point mutations with low allele frequencie
Externí odkaz:
https://doaj.org/article/8dc8ff30f63041339c691b909a112cf3
Autor:
Samuel Amintas, Benjamin Fernandez, Alexandre Chauvet, Laurence Chiche, Christophe Laurent, Geneviève Belleannée, Marion Marty, Etienne Buscail, Sandrine Dabernat
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Pancreatic ductal adenocarcinoma (PDAC) patients eligible for curative surgery undergo unpredictable disease relapse. Even patients with a good pathological response after neoadjuvant treatment (NAT) remain susceptible to recurrent PDAC. Mol
Externí odkaz:
https://doaj.org/article/299fe5686228497aba75633c35a1b10c
Autor:
Samuel Amintas, Pauline Beaumont, Charles Dupin, Isabelle Moranvillier, Isabelle Lamrissi, Elie Patel, Benjamin Fernandez, Alice Bibeyran, Julian Boutin, Tristan Richard, Stéphanie Krisa, François Moreau-Gaudry, Aurélie Bedel, David Cappellen, Benoît Pinson, Véronique Vendrely, Sandrine Dabernat
Publikováno v:
Journal of Functional Foods, Vol 99, Iss , Pp 105345- (2022)
Resveratrol belongs to the Bioactive Food Component (BFC) family. It seems admitted that its cytotoxic action impacts tumor cells and spares healthy cells, but the published proofs remain rare. We hypothesized that cells may differentially metabolize
Externí odkaz:
https://doaj.org/article/a6b60731bfbd48399c87283fc03376bc
Autor:
Camille Luherne, Sarah Menguy, Thomas Ferte, Marie Beylot-Barry, Julien Seneschal, Brigitte Milpied, Jean-Philippe Vial, Audrey Gros, Samuel Amintas, Béatrice Vergier, Anne Pham-Ledard
Publikováno v:
Acta Dermato-Venereologica, Vol 102 (2022)
Erythroderma is challenging to diagnose. The aim of this single-centre retrospective study was to identify factors that can be used to improve the diagnosis of erythroderma. Among 91 patients with erythroderma, 21 were diagnosed with eczema, 17 with
Externí odkaz:
https://doaj.org/article/9a86db24288447fe8c2fd49ec14692e8
Next-Generation Cancer Biomarkers: Extracellular Vesicle DNA as a Circulating Surrogate of Tumor DNA
Autor:
Samuel Amintas, Véronique Vendrely, Charles Dupin, Louis Buscail, Christophe Laurent, Barbara Bournet, Jean-Philippe Merlio, Aurélie Bedel, François Moreau-Gaudry, Julian Boutin, Sandrine Dabernat, Etienne Buscail
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Extracellular vesicles (EVs) are produced by healthy tissues and tumor cells and are released in various bodily fluids, including blood. They are limited by bilayer phospholipidic membranes, and they carry a rich content in biomolecules. Their releas
Externí odkaz:
https://doaj.org/article/8b80cec79fc643f28a9fb04db7bebb51
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-19 (2018)
Abstract Acid ceramidase (ACDase) deficiency is a spectrum of disorders that includes a rare lysosomal storage disorder called Farber disease (FD) and a rare epileptic disorder called spinal muscular atrophy with progressive myoclonic epilepsy (SMA-P
Externí odkaz:
https://doaj.org/article/87be9b5c6efa48b8b2b88681ab87bdd7
Autor:
Samuel, Amintas, Charles, Dupin, Julian, Boutin, Pauline, Beaumont, François, Moreau-Gaudry, Aurélie, Bedel, Stéphanie, Krisa, Véronique, Vendrely, Sandrine, Dabernat
Publikováno v:
Critical Reviews in Food Science and Nutrition. :1-15
Colorectal cancer (CRC) is the third most frequent cancer worldwide, accounts for about 10% of the total cancer cases, and ranks as the second cause of death by cancer. CRC is more prevalent in developed countries in close causal relation with occide
Autor:
Jean-Marc Blouin, F. Prat, J. Rosier, Jean-Philippe Merlio, J. Bouron, Emmanuel Richard, Cécile Ged, Julian Boutin, Isabelle Lamrissi-Garcia, Aurélie Bedel, Sandrine Dabernat, François Moreau-Gaudry, G. Cullot, J. Toutain, Caroline Rooryck, Perrine Pennamen, Véronique Guyonnet-Dupérat, D. Cappellen, Samuel Amintas
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-25190-6⟩
Nature Communications, 2021, 12 (1), ⟨10.1038/s41467-021-25190-6⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-25190-6⟩
Nature Communications, 2021, 12 (1), ⟨10.1038/s41467-021-25190-6⟩
CRISPR-Cas9 is a promising technology for gene therapy. However, the ON-target genotoxicity of CRISPR-Cas9 nuclease due to DNA double-strand breaks has received little attention and is probably underestimated. Here we report that genome editing targe
Autor:
Pietro Rosellini, Samuel Amintas, Charline Caumont, Rémi Veillon, Sigolène Galland-Girodet, Alain Cuguillière, Laurent Nguyen, Charlotte Domblides, Amandine Gouverneur, Jean-Philippe Merlio, Julien Bezin, Pierre-Olivier Girodet
Publikováno v:
European journal of cancer (Oxford, England : 1990). 172
Mutations in STK11/LKB1 gene present a negative impact on tumour immune microenvironment, especially with concomitant activating KRAS mutation. These recent data may explain a decreased response to immunotherapy treatment in STK11 mutant non-small ce
Autor:
Come Sesboue, Jean Galtier, Marie Jeanneau, Annick Chauvel, Elodie Laharanne, Samuel Amintas, Jean-Philippe Merlio, Krimo Bouabdallah, François-Xavier Gros, Laurence de Leval, Audrey Gros, Marie Parrens
Publikováno v:
Modern Pathology. 36:100043