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Autor:
Ljubica Krsmanovic, Michelle Klug Laforce, Madhav Paranjpe, Sandra Springer, Samual Atta-Safoh, Kathleen Szabo, Fekado Debelie, Jing Shi, Mirna Arevalo, Shannon W. Bruce, Jamie E. Sly, Tawney Kelly
Publikováno v:
Environmental and molecular mutagenesis. 52(9)
As part of the Stage 3 of the Pig-a international trial, we evaluated 7,12-dimethylbenz(a)anthracene (DMBA) for induction of Pig-a gene mutation using a 28-day repeat dose study design in Sprague-Dawley rats. In the same study, chromosomal damage in