Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Samu Myllymaa"'
Autor:
Theresa E. Hickey, Olli Ritvos, Lesley J. Ritter, Noora Kaivo-Oja, Robert B. Gilchrist, R Dragovic, Samu Myllymaa, David G. Mottershead
Publikováno v:
Journal of Cell Science. 119:3811-3821
Oocytes regulate follicle growth by secreting paracrine growth factors that act on neighbouring granulosa cells (GCs). Those factors identified to date are mainly members of the transforming growth factor-beta (TGFbeta) superfamily, but little is kno
Autor:
Katri Koli, Mika Laitinen, Pranuthi Muggalla, David G. Mottershead, Helen Ludlow, Samu Myllymaa, Olli Ritvos, Arja Pasternack, Minna M. Pulkki, Peter ten Dijke, Maarten van Dinther
Publikováno v:
Endocrinology, 153(3), 1509-1518
Genetic studies have identified bone morphogenetic protein-15 (BMP15) as an essential regulator of female fertility in humans and in sheep. Oocyte-derived BMP15 is a noncovalently linked dimeric growth factor mediating its effects to ovarian somatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abfa2b80e13f0196f1239506ad7a7160
https://doi.org/10.1210/en.2010-1390
https://doi.org/10.1210/en.2010-1390
Autor:
Samu Myllymaa, Helen Ludlow, David G. Mottershead, Nigel P. Groome, Olexandr Korchynskyi, Arja Pasternack, Ahmed Al-Qahtani, Olli Ritvos, Minna M. Pulkki, Nisse Kalkkinen, S. Lun, Jennifer L. Juengel, Mika Laitinen
Publikováno v:
Molecular and Cellular Endocrinology
Molecular and Cellular Endocrinology, Elsevier, 2010, 332 (1-2), pp.106. ⟨10.1016/j.mce.2010.10.002⟩
Molecular and Cellular Endocrinology, Elsevier, 2010, 332 (1-2), pp.106. ⟨10.1016/j.mce.2010.10.002⟩
International audience; Oocyte-derived bone morphogenetic protein-15 (BMP15) is critical for the regulation of mammalian fertility. Previously we have found that a C-terminal His-tag destroys the bioactivity of growth differentiation-9 (GDF9, a homol
Autor:
Samu Myllymaa, Minna M. Pulkki, Lauri J. Pelliniemi, Arja Pasternack, David G. Mottershead, Mika Laitinen, Matti Poutanen, Olli Ritvos
Publikováno v:
Reproduction (Cambridge, England). 139(3)
Growth differentiation factor-9 (GDF9) and bone morphogenetic protein-15 (BMP15) are among the key regulators transmitting the signaling between the oocyte and the surrounding granulosa cells. Previously, it has been shown that a recombinant BMP type
Autor:
Jennifer L. Juengel, Olli Ritvos, Stan Lun, Pranuthi Muggalla, Olexandr Korchynskyi, Yoshihiro Nishi, Minna Tolonen, Samu Myllymaa, Toshihiko Yanase, Arja Pasternack, David G. Mottershead, Minna M. Pulkki, Mika Laitinen
Publikováno v:
Molecular and Cellular Endocrinology
Molecular and Cellular Endocrinology, Elsevier, 2008, 283 (1-2), pp.58. ⟨10.1016/j.mce.2007.11.007⟩
Molecular and Cellular Endocrinology, Elsevier, 2008, 283 (1-2), pp.58. ⟨10.1016/j.mce.2007.11.007⟩
Growth differentiation factor-9 (GDF9) is an oocyte secreted paracrine factor essential for mammalian ovarian folliculogenesis. Like other members of the transforming growth factor-beta (TGFbeta) superfamily, GDF9 is synthesized as a prepropeptide wh
Autor:
David G. Mottershead, Andrea Western, Kenneth P. McNatty, Olli Ritvos, Mika Laitinen, Samu Myllymaa, Stan Lun, Steve Lawrence, Nigel P. Groome, Jennifer L. Juengel, Karen L Reader, Mohamed F Meerasahib
Publikováno v:
Reproduction (Cambridge, England). 129(4)
The oocyte-secreted polypeptide growth factors, growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15, also known as GDF9B) have both been shown to be essential for ovarian follicular development and ovulation rate. In addit
Autor:
Nigel P. Groome, Mika Laitinen, Kenneth P. McNatty, Andrea Western, David G. Mottershead, Samu Myllymaa, Steve Lawrence, Karen L Reader, Olli Ritvos, Stan Lun, Jennifer L. Juengel, Mohamed F Meerasahib
Publikováno v:
Reproduction (Cambridge, England). 129(4)
The oocyte-secreted polypeptide growth factors, growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15, also known as GDF9B) have both been shown to be essential for ovarian follicular growth and function. The effects of muri
Autor:
David G. Mottershead, R. B. Gilchrist, Noora Kaivo-Oja, Samu Myllymaa, Lesley J. Ritter, Olli Ritvos, F. Amato
Publikováno v:
Reproduction, Fertility and Development. 16:247
Oocytes regulate follicle growth and development by secreting paracrine growth factors that act on granulosa cells (GC). We have recently determined that growth differentiation factor-9 (GDF-9) accounts for ~50% of the total mitogenic activity of ooc
Autor:
Lesley J. Ritter, R. B. Gilchrist, F. Amato, Hilkka Lankinen, Mark Cranfield, David G. Mottershead, Olli Ritvos, N. P. Groome, Luke Jeffery, Samu Myllymaa
Publikováno v:
Reproduction, Fertility and Development. 15:93