Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Samson Fung"'
Autor:
Michael Wang, Hans-Jörg Hertfelder, Elyse Swallow, Alexandra Greatsinger, Emma Billmyer, Samson Fung, Peter L. Turecek, Hanna T. Gazda, Csaba Siffel
Publikováno v:
Thrombosis Update, Vol 14, Iss , Pp 100159- (2024)
Introduction: Replacement therapy with intravenous (IV) protein C concentrate (Ceprotin®; Baxalta US Inc., a Takeda company, Lexington, MA, USA; Takeda Manufacturing Austria AG, Vienna, Austria) is an approved treatment approach for patients with se
Externí odkaz:
https://doaj.org/article/f3df5e87cbf74ca7849c3d2e702bd4b3
Autor:
Thomas Pabst, Norbert Vey, Lionel Adès, Ulrike Bacher, Mario Bargetzi, Samson Fung, Gianluca Gaidano, Domenica Gandini, Anna Hultberg, Amy Johnson, Xuewen Ma, Rouven Müller, Kerri Nottage, Cristina Papayannidis, Christian Recher, Carsten Riether, Priya Shah, Jeffrey Tryon, Liang Xiu, Adrian F. Ochsenbein
Publikováno v:
Haematologica, Vol 108, Iss 7 (2023)
Cusatuzumab is a high-affinity, anti-CD70 monoclonal antibody under investigation in acute myeloid leukemia (AML). This two-part, open-label, multicenter, phase I/II trial evaluated cusatuzumab plus azacitidine in patients with newly diagnosed AML in
Externí odkaz:
https://doaj.org/article/44a72b022e1b4366bad1fca7a93513e4
Autor:
Astrid De Meulenaere, Tijl Vermassen, David Creytens, Stijn De Keukeleire, Tim Delahaye, Philippe Deron, Fréderic Duprez, Samson Fung, Patrick Pauwels, Liesbeth Ferdinande, Sylvie Rottey
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 6, Pp 2300-2313 (2021)
Abstract CD70 is expressed in up to 80% of nasopharyngeal carcinoma (NPC) cases. Cusatuzumab is a humanized anti‐CD70 monoclonal antibody, with dual action mechanisms: induction of cytotoxicity against CD70+ tumor cells and reduction in CD70‐CD27
Externí odkaz:
https://doaj.org/article/d937f00205db456b849d7045bb391b76
Autor:
Philippe Aftimos, Christian Rolfo, Sylvie Rottey, Philippe Barthélémy, Christophe Borg, Keunchil Park, Do-Youn Oh, Sang-We Kim, Natalie De Jonge, Valérie Hanssens, Karen Zwanenpoel, Carla Molthoff, Daniëlle Vugts, Torsten Dreier, Peter Verheesen, Guus A.M.S. van Dongen, Julie Jacobs, Luc Van Rompaey, Anna Hultberg, Paolo Michieli, Patrick Pauwels, Samson Fung, Alain Thibault, Hans de Haard, Nicolas Leupin, Ahmad Awada
Publikováno v:
Biomedicines, Vol 9, Iss 6, p 665 (2021)
Dysregulation of MET signaling has been implicated in tumorigenesis and metastasis. ARGX-111 combines complete blockade of this pathway with enhanced tumor cell killing and was investigated in 24 patients with MET-positive advanced cancers in a phase
Externí odkaz:
https://doaj.org/article/f221f0cc086e421e96736936b19db3e0
Autor:
Stefanie Fischer, Thorsten O. Götze, Aurelius Omlin, Richard D. Baird, Keith M. Dawson, Christof Zitt, Zita Arany, Gaby Tresch, Ulrike Fiedler, Simone Jeger, Samson Fung, Philippe Legenne, Nicolas Leupin, Andreas Schneeweiss, Carlo Fremd
Publikováno v:
JCO precision oncology. 6
The human epidermal growth factor receptor 2 (HER2, ERBB2) is amplified or overexpressed in approximately 20% of breast cancers. HER2 amplification results in increased homodimerization and HER3 heterodimerization, with HER2/HER3 heterodimers promoti
Autor:
Torsten Dreier, Sang We Kim, Christophe Borg, Peter Verheesen, Carla F. M. Molthoff, Philippe Barthélémy, Danielle J. Vugts, Paolo Michieli, Keunchil Park, Guus A.M.S. van Dongen, Luc Van Rompaey, Do Youn Oh, Natalie De Jonge, Karen Zwanenpoel, Christian Rolfo, Philippe Aftimos, Nicolas Leupin, Alain Thibault, Ahmad Awada, Sylvie Rottey, Valérie Hanssens, Julie Jacobs, Samson Fung, Patrick Pauwels, Hans de Haard, Anna Hultberg
Publikováno v:
Biomedicines
Biomedicines, Vol 9, Iss 665, p 665 (2021)
BIOMEDICINES
Biomedicines, 9(6). MDPI AG
Biomedicines, 9(6):665. MDPI AG
Biomedicines, 9 (6
Aftimos, P, Rolfo, C, Rottey, S, Barthélémy, P, Borg, C, Park, K, Oh, D-Y, Kim, S-W, de Jonge, N, Hanssens, V, Zwanenpoel, K, Molthoff, C, Vugts, D, Dreier, T, Verheesen, P, van Dongen, G A M S, Jacobs, J, van Rompaey, L, Hultberg, A, Michieli, P, Pauwels, P, Fung, S, Thibault, A, de Haard, H, Leupin, N & Awada, A 2021, ' The nhance® mutation-equipped anti-met antibody argx-111 displays increased tissue penetration and anti-tumor activity in advanced cancer patients ', Biomedicines, vol. 9, no. 6, 665 . https://doi.org/10.3390/biomedicines9060665
Volume 9
Issue 6
Biomedicines, Vol 9, Iss 665, p 665 (2021)
BIOMEDICINES
Biomedicines, 9(6). MDPI AG
Biomedicines, 9(6):665. MDPI AG
Biomedicines, 9 (6
Aftimos, P, Rolfo, C, Rottey, S, Barthélémy, P, Borg, C, Park, K, Oh, D-Y, Kim, S-W, de Jonge, N, Hanssens, V, Zwanenpoel, K, Molthoff, C, Vugts, D, Dreier, T, Verheesen, P, van Dongen, G A M S, Jacobs, J, van Rompaey, L, Hultberg, A, Michieli, P, Pauwels, P, Fung, S, Thibault, A, de Haard, H, Leupin, N & Awada, A 2021, ' The nhance® mutation-equipped anti-met antibody argx-111 displays increased tissue penetration and anti-tumor activity in advanced cancer patients ', Biomedicines, vol. 9, no. 6, 665 . https://doi.org/10.3390/biomedicines9060665
Volume 9
Issue 6
Dysregulation of MET signaling has been implicated in tumorigenesis and metastasis. ARGX-111 combines complete blockade of this pathway with enhanced tumor cell killing and was investigated in 24 patients with MET-positive advanced cancers in a phase
Autor:
Adrian F. Ochsenbein, Ulrike Bacher, Hans de Haard, Ellen Erzeel, David Francisco, Anna Hultberg, Samson Fung, Magdalena Hinterbrandner, Markus G. Manz, Yara Banz, Mahan Moshir, Thomas Pabst, Tim Delahaye, Luc Van Rompaey, Sabine Höpner, Rouven Müller, Carsten Riether, Domenica Gandini, Walid H. Gharib, Rémy Bruggmann, Nicolas Leupin
Acute myeloid leukemia (AML) is driven by leukemia stem cells (LSCs) that resist conventional chemotherapy and are the major cause of relapse1,2. Hypomethylating agents (HMAs) are the standard of care in the treatment of older or unfit patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69bd75a7a31c6457437ffc638a812048
https://www.zora.uzh.ch/id/eprint/190892/
https://www.zora.uzh.ch/id/eprint/190892/
Autor:
Debra Barker, Barbara Romagnoli, Jose Perez-Garcia, Cristina Hernando, Linda T. Vahdat, Miguel Martin, Peter A. Kaufman, Eva Ciruelos, Katherine N. Weilbaecher, Sara López-Tarruella, Maria Martinez Garcia, Patricia Gomez Pardo, Sonia Pernas, Foluso O. Ademuyiwa, Samson Fung, Luis Manso, Jose Alejandro Perez-Fidalgo, Timothy J. Pluard, Javier Cortes, Ingrid A. Mayer, M. Gil-Martin, Achim Wach
Publikováno v:
The Lancet. Oncology
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Summary Background The C-X-C chemokine receptor type 4 (CXCR4)–stromal cell-derived factor-1α (SDF-1α) axis regulates function and trafficking of immune cells and the tumour microenvironment. CXCR4 antagonists have been shown to enhance the activ
Autor:
Walid H. Gharib, Rouven Müller, Samson Fung, Mahan Moshir, Tim Delahaye, Yara Banz, Hans de Haard, Thomas Pabst, Rémy Bruggmann, Adrian F. Ochsenbein, Ellen Erzeel, Luc Van Rompaey, Sabine Höpner, Markus G. Manz, Carsten Riether, David Francisco, Nicolas Leupin, Domenica Gandini, Vera Ulrike Bacher, Magdalena Hinterbrandner, Anna Hultberg
Publikováno v:
Blood. 134:234-234
Introduction Acute myeloid leukemia (AML) is a heterogenous hematological malignancy driven by leukemia stem cells (LSCs) (Lapidot et al, 1994). LSCs resistant against conventional chemotherapy represent the major cause of relapse. Elderly or unfit A
Autor:
Yara Banz, Samson Fung, Markus G. Manz, Carsten Riether, Sabine Höpner, Hans de Haard, Tim Delahaye, Anna Hultberg, Thomas Pabst, Adrian F. Ochsenbein, Domenica Gandini, Mahan Moshir, Rouven Müller, Luc Van Rompaey, Ulrike Bacher, Ellen Erzeel, Mario Bargetzi, Magdalena Hinterbrandner, Nicolas Leupin
Publikováno v:
Blood. 132:2680-2680
Outcomes in elderly patients with acute myeloid leukemia (AML) are still adverse, as the majority does not qualify for intensive therapy or allogenic stem cell transplantation (ASCT). DNA hypomethylating agents (HMAs) induce remissions and prolong su