Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Samsher Singh"'
Autor:
Priya Ragunathan, Pearly Shuyi Ng, Samsher Singh, Wee Han Poh, Dennis Litty, Nitin Pal Kalia, Simon Larsson, Amaravadhi Harikishore, Scott A. Rice, Philip W. Ingham, Volker Müller, Garrett Moraski, Marvin J. Miller, Thomas Dick, Kevin Pethe, Gerhard Grüber
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT The Mycobacterium tuberculosis (Mtb) F-ATP synthase generates most of the biological energy currency ATP. Previously, we identified the mycobacterium-specific loop of the F-ATP synthase subunit γ as a new anti-tuberculosis target and discov
Externí odkaz:
https://doaj.org/article/326a564021ea4d0fb1574e9e794a038f
Autor:
Mousumi Shyam, Gourab Bhattacharje, Chris Daniel, Amrendra Kumar, Pragya Yadav, Piyali Mukherjee, Samsher Singh, Amit Kumar Das, Tadigoppula Narender, Amit Singh, Venkatesan Jayaprakash, Sanjib Bhakta
Publikováno v:
Molecules, Vol 28, Iss 24, p 8115 (2023)
The uncontrolled spread of drug-resistant tuberculosis (DR-TB) clinical cases necessitates the urgent discovery of newer chemotypes with novel mechanisms of action. Here, we report the chemical synthesis of rationally designed novel transition-state
Externí odkaz:
https://doaj.org/article/05e022cb8178435aaf84fe49218a3c2f
Autor:
Nitin Pal Kalia, Samsher Singh, Kiel Hards, Chen-Yi Cheung, Ekaterina Sviriaeva, Amir Banaei-Esfahani, Ruedi Aebersold, Michael Berney, Gregory M. Cook, Kevin Pethe
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112444- (2023)
Summary: The bioenergetic mechanisms by which Mycobacterium tuberculosis survives hypoxia are poorly understood. Current models assume that the bacterium shifts to an alternate electron acceptor or fermentation to maintain membrane potential and ATP
Externí odkaz:
https://doaj.org/article/9d80392a417e4e81ac7c55890f889fb7
Autor:
Samsher Singh, Nitin P. Kalia, Prashant Joshi, Ajay Kumar, Parduman R. Sharma, Ashok Kumar, Sandip B. Bharate, Inshad A. Khan
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
This study elucidated the role of boeravinone B, a NorA multidrug efflux pump inhibitor, in biofilm inhibition. The effects of boeravinone B plus ciprofloxacin, a NorA substrate, were evaluated in NorA-overexpressing, wild-type, and knocked-out Staph
Externí odkaz:
https://doaj.org/article/cbeae651956941dc88fa1cd60875d17b
Autor:
Ravindra, Khaiwal, Bahadur, Samsher Singh, Katoch, Varun, Bhardwaj, Sanjeev, Kaur-Sidhu, Maninder, Gupta, Madhu, Mor, Suman
Publikováno v:
In Science of the Total Environment 1 February 2023 858 Part 1
Autor:
Samsher Singh, Dr. Kishor Jose
Publikováno v:
Towards Excellence. :1015-1020
The Intergovernmental Panel on Climate Change’s (IPCC) described climate change as long-term changes in temperature, humidity, clouds, and rainfall and not to routine variations (IPCC 2007). Inevitably, Climate change is the matter of critical conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c13d3551043f9c1edc0084fc890f3d0
https://doi.org/10.37867/te140489
https://doi.org/10.37867/te140489
Autor:
Boon Chong Goh, Simon Larsson, Linh Chi Dam, Yan Han Sharon Ling, Wei Lin Patrina Chua, R Abirami, Samsher Singh, Jun Long Ernest Ong, Jeanette W P Teo, Peiying Ho, Philip W Ingham, Kevin Pethe, Peter C Dedon
Publikováno v:
JAC-Antimicrobial Resistance. 5
Background Mycobacterium abscessus is a non-tuberculous mycobacterium (NTM) that causes chronic pulmonary infections. Because of its extensive innate resistance to numerous antibiotics, treatment options are limited, often resulting in poor clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::736b872c36747435a29a4c0197727ef5
https://doi.org/10.1093/jacamr/dlad052
https://doi.org/10.1093/jacamr/dlad052
Autor:
Somnath Shee, Samsher Singh, Ashutosh Tripathi, Chandrani Thakur, Anand Kumar T, Mayashree Das, Vikas Yadav, Sakshi Kohli, Raju S. Rajmani, Nagasuma Chandra, Harinath Chakrapani, Karl Drlica, Amit Singh
Publikováno v:
Antimicrob Agents Chemother
Moxifloxacin is central to treatment of multidrug-resistant tuberculosis. Effects of moxifloxacin on the Mycobacterium tuberculosis redox state were explored to identify strategies for increasing lethality and reducing the prevalence of extensively r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e86c00cd0c5de6781c9c7a63e9ba2781
https://doi.org/10.1128/aac.00592-22
https://doi.org/10.1128/aac.00592-22
Publikováno v:
Current Opinion in Microbiology. 74:102327
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35e318f19fa7a8d1fee4eb5f565cf5d0
https://doi.org/10.1016/j.mib.2023.102327
https://doi.org/10.1016/j.mib.2023.102327
14-Residue peptaibol velutibol A from Trichoderma velutinum: its structural and cytotoxic evaluation
Autor:
Samsher Singh, Varun Pratap Singh, Fayaz Malik, Deepika Singh, Manoj Kushwaha, Anil Kumar, Ram A. Vishwakarma, Inshad A. Khan, Vandana Sharma, Anup Singh Pathania
Publikováno v:
RSC Advances. 10:31233-31242
Velutibol A (1), a new 14-residue peptaibol was isolated from the Himalayan cold habitat fungus Trichoderma velutinum. The structural characterization was carried out by 1D and 2D NMR studies, and tandem mass studies, and Marfey's method aided in det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4ca926646cb120bd708dfbe586897d7
https://doi.org/10.1039/d0ra05780k
https://doi.org/10.1039/d0ra05780k