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pro vyhledávání: '"Samridhi Lal"'
Autor:
Subash Chandra Gupta, Anurag Sharma, Divya Vimal, Leonard Clinton D’Souza, Vipin Rai, Samridhi Lal
Publikováno v:
Current Medicinal Chemistry. 30:178-202
Abstract: There is a long history of informal use of Cannabis sativa (commonly called cannabis) for many purposes, including treating various ailments worldwide. However, the legalization of cannabis in multiple countries, specifically for medical pu
Background: Arylindole derivatives are promising scaffolds in the design of new drugs. These scaffolds exhibit a wide biological activity, including inhibition of COX-2, antitumor activity, receptor GABA agonism, and estrogen receptor modulation. Obj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b58d90f21f877b81ef0c112ac93b1f
https://hdl.handle.net/2086/22570
https://hdl.handle.net/2086/22570
Autor:
Arun K. Sharma, Akash Sharma, Samridhi Lal, Ashish Kumar, Nirmala K. Yadav, Fauzia Tabassum, Md. Sayeed Akhtar, Mohammad Tarique Imam, Ziyad Saeed Almalki, Monalisa Mukherjee
Publikováno v:
Drug Discovery Today. 28:103558
Publikováno v:
Pharmacological research. 163
Cannabis has long been used for healing and recreation in several regions of the world. Over 400 bioactive constituents, including more than 100 phytocannabinoids, have been isolated from this plant. The non-psychoactive cannabidiol (CBD) and the psy
Autor:
Samridhi Lal, Timothy J. Snape
Publikováno v:
Drug discovery today. 26(2)
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link. Central nervous system (CNS) cancers are among the most aggressive and devastating. Furthermore, becau
Autor:
Timothy J. Snape, Samridhi Lal
Publikováno v:
RSC Adv.. 4:1609-1615
A general, catalytic and sustainable synthesis of amides has been targeted which utilises a chemoenzymatic step to generate an activated amide coupling partner in situ. A screen of a series of known activating agents was performed and the successful
Autor:
Samridhi Lal, Timothy J. Snape
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 83:80-86
An efficient biocatalytic method has been developed which provides acetanilides in good yields which are otherwise inaccessible using Candida antarctica lipase B. The process exploits the enzyme-catalysed synthesis of an acyl donor and its in situ re
Autor:
Samridhi Lal, Timothy J. Snape
Publikováno v:
Medical hypotheses. 83(6)
It is firmly established that control over the three-dimensional shape (i.e., the conformation) of aromatic amides and ureas can be achieved using a variety of methods, all of which rely on the addition of a substituent to a central nitrogen atom; ex
Autor:
Timothy J. Snape, Samridhi Lal
Publikováno v:
Current medicinal chemistry. 19(28)
Privileged structures bind to multiple receptors with high affinity, thus aiding the development of novel biologically active compounds. Indoles are classed as privileged structures, and as a result of the indole nucleus being present in a broad rang
Autor:
Cuppoloni A; Department of Pharmacy, School of Pharmaceutical Sciences, University of Sao Paulo, São Paulo, Brazil., Silva JV; Department of Pharmacy, School of Pharmaceutical Sciences, University of Sao Paulo, São Paulo, Brazil., Snape TJ; Leicester School of Pharmacy, De Montfort University, Leicester, LE1 9BH, UK., Lal S; Amity Institute of Pharmacy, Samridhi Lal, Amity University, Gurugram, India., Giarolla J; Department of Pharmacy, School of Pharmaceutical Sciences, University of Sao Paulo, São Paulo, Brazil.
Publikováno v:
Current topics in medicinal chemistry [Curr Top Med Chem] 2023; Vol. 23 (12), pp. 1081-1089.