Rhus coriaria increases protein ubiquitination, proteasomal degradation and triggers non-canonical Beclin-1-independent autophagy and apoptotic cell death in colon cancer cells.

Autor: Athamneh K; Department of Biology, College of Science, United Arab Emirates University, Al-Ain, P.O. Box 15551, United Arab Emirates., Hasasna HE; Department of Biology, College of Science, United Arab Emirates University, Al-Ain, P.O. Box 15551, United Arab Emirates., Samri HA; Department of Biology, College of Science, United Arab Emirates University, Al-Ain, P.O. Box 15551, United Arab Emirates., Attoub S; Department of Pharmacology & Therapeutics, College of Medicine & Health Sciences, United Arab Emirates University, Al-Ain, P.O. Box: 17666, United Arab Emirates., Arafat K; Department of Pharmacology & Therapeutics, College of Medicine & Health Sciences, United Arab Emirates University, Al-Ain, P.O. Box: 17666, United Arab Emirates., Benhalilou N; Department of Biology, College of Science, United Arab Emirates University, Al-Ain, P.O. Box 15551, United Arab Emirates., Rashedi AA; Department of Biology, College of Science, United Arab Emirates University, Al-Ain, P.O. Box 15551, United Arab Emirates., Dhaheri YA; Department of Biology, College of Science, United Arab Emirates University, Al-Ain, P.O. Box 15551, United Arab Emirates., AbuQamar S; Department of Biology, College of Science, United Arab Emirates University, Al-Ain, P.O. Box 15551, United Arab Emirates., Eid A; Department of Pharmacology and Toxicology, Faculty of Medicine, American University of Beirut, Beirut, PO Box 11-0236, Lebanon., Iratni R; Department of Biology, College of Science, United Arab Emirates University, Al-Ain, P.O. Box 15551, United Arab Emirates. R_iratni@uaeu.ac.ae.

Publikováno v: Scientific reports [Sci Rep] 2017 Sep 14; Vol. 7 (1), pp. 11633. Date of Electronic Publication: 2017 Sep 14.