Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Samra Lazarus"'
Autor:
Loc Le, Sabiha Khatoon, Paola Jiménez, Christopher Peterson, Rebecca Kernen, Weidong Zhang, Adebayo J. Molehin, Samra Lazarus, Justin Sudduth, Jordan May, Souvik Karmakar, Juan U. Rojo, Gul Ahmad, Workineh Torben, David Carey, Roman F. Wolf, James F. Papin, Afzal A. Siddiqui
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-7 (2020)
Abstract Background Schistosomiasis continues to inflict significant morbidity and mortality in the tropical and subtropical regions of the world. The disease endemicity overlaps with the transmission of other parasitic diseases. Despite the ubiquity
Externí odkaz:
https://doaj.org/article/31d4e4b20d374e19ac1e34c514356c13
Autor:
Michael W. Melkus, Loc Le, Arif J. Siddiqui, Adebayo J. Molehin, Weidong Zhang, Samra Lazarus, Afzal A. Siddiqui
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
For decades, mass drug treatment with praziquantel (PZQ) has been utilized to treat schistosomiasis, yet reinfection and the risk of drug resistance are among the various factors precluding successful elimination of schistosomiasis. Tractable models
Externí odkaz:
https://doaj.org/article/261fc6ad3ef94760b73799ea6a470581
Autor:
Weidong Zhang, Juan U. Rojo, Christopher Peterson, Souvik Karmakar, Rebecca Kernen, Samra Lazarus, Jordan May, Justin Sudduth, Gul Ahmad, Afzal A. Siddiqui, James F. Papin, Paola Jiménez, Adebayo J. Molehin, Roman F. Wolf, David W. Carey, Sabiha Khatoon, Workineh Torben, Loc Le
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-7 (2020)
Parasites & Vectors
Parasites & Vectors
Background Schistosomiasis continues to inflict significant morbidity and mortality in the tropical and subtropical regions of the world. The disease endemicity overlaps with the transmission of other parasitic diseases. Despite the ubiquity of polyp
Autor:
Darrick Carter, Afzal A. Siddiqui, Adebayo J. Molehin, Gul Ahmad, Eunjee Kim, Samra Lazarus, Loc Le, Arif Jamal Siddiqui, Weidong Zhang, Workineh Torben
Publikováno v:
Journal of Investigative Medicine
Sm-p80, the large subunit of Schistosoma mansoni calpain, is a leading candidate for a schistosomiasis vaccine. The prophylactic and antifecundity efficacy of Sm-p80 has been tested in three animal models (mouse, hamster and baboon) using a multitude
Autor:
Jenn D. Bergthold, Loc Le, Sean A. Gray, Roman F. Wolf, Kameswara Rao Kottapalli, Whitni K. Redman, Steven G. Reed, Jasmin Freeborn, Arif Jamal Siddiqui, Raymond T. Damian, Darrick Carter, Pramodh K. Ganapathy, David W. Carey, Justin Sudduth, James F. Papin, Afzal A. Siddiqui, Weidong Zhang, Juan U. Rojo, Eunjee Kim, Souad R. Sennoune, Adebayo J. Molehin, Workineh Torben, Jordan May, Bryan T. Mayer, Catherine Nguyen, Pratibha Kottapalli, Gul Ahmad, Florian Marks, Souvik Karmakar, Samra Lazarus
Publikováno v:
Annals of the New York Academy of Sciences. 1425:38-51
Schistosomiasis is of public health importance to an estimated one billion people in 79 countries. A vaccine is urgently needed. Here, we report the results of four independent, double-blind studies of an Sm-p80-based vaccine in baboons. The vaccine