Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sampsa T. Sipilä"'
Publikováno v:
Journal of Neuroscience. 34:10003-10009
Although functional glycinergic synapses have not been identified in the hippocampus, neurons in this area express Cl(−) permeable extrasynaptic glycine receptors (GlyRs). In experiments on CA3 pyramidal neurons on postnatal day 0–6 rat hippocamp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853eaf04c34224158d3d6e6633f66a26
https://doi.org/10.1523/jneurosci.0075-13.2014
https://doi.org/10.1523/jneurosci.0075-13.2014
Publikováno v:
European Journal of Neuroscience. 25:717-722
Tonic activation of GABA(A) receptors takes place before the development of functional synapses in cortical structures. We studied whether inefficient GABA uptake might explain the presence of a tonic GABA(A)-mediated current (I(GABA-A)) in early pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56501552b4b90a65a92354f41456b615
https://doi.org/10.1111/j.1460-9568.2007.05342.x
https://doi.org/10.1111/j.1460-9568.2007.05342.x
Autor:
Ken Mackie, Kai Kaila, Claudio Rivera, Juha Voipio, Sebastian Schuchmann, Dietmar Schmitz, Sampsa Vanhatalo, Benedikt Salmen, Sampsa T. Sipilä
Publikováno v:
Nature Medicine. 12:817-823
Febrile seizures are frequent during early childhood, and prolonged (complex) febrile seizures are associated with an increased susceptibility to temporal lobe epilepsy. The pathophysiological consequences of febrile seizures have been extensively st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41118c67ae21db42e236f8e72f6d0798
https://doi.org/10.1038/nm1422
https://doi.org/10.1038/nm1422
Publikováno v:
The Journal of Physiology. 573:765-773
Earlier studies indicate a crucial role for the interconnected network of intrinsically bursting CA3 pyramidal neurons in the generation of in vivo hippocampal sharp waves (SPWs) and their proposed neonatal in vitro counterparts, the giant depolarizi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cff3b2d8d56bcd81fe607e0f69c8ba9d
https://doi.org/10.1113/jphysiol.2006.107086
https://doi.org/10.1113/jphysiol.2006.107086
Publikováno v:
European Journal of Neuroscience. 23:2330-2338
The CA3 area of the mature hippocampus is known for its ability to generate intermittent network activity both in physiological and in pathological conditions. We have recently shown that in the early postnatal period, the intrinsic bursting of inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b5f9c52a1c0b26b2e8db8d2ffb5ce4
https://doi.org/10.1111/j.1460-9568.2006.04757.x
https://doi.org/10.1111/j.1460-9568.2006.04757.x
Autor:
Liisa Paavilainen, Synnöve Carlson, Sampsa T. Sipilä, Pia Rämä, Kimmo Alho, Irina Anourova, K. Reinikainen
Publikováno v:
University of Helsinki
Slow event-related brain potentials were recorded from the human scalp during spatial and nonspatial auditory delayed matching-to-sample and n-back tasks to find out whether there are differences in the distribution of slow potentials during the rete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e377398363475b351a80951a01199be
https://doi.org/10.1016/s0028-3932(00)00019-1
https://doi.org/10.1016/s0028-3932(00)00019-1
Autor:
Kai Kaila, Junko Yamada, Ramil Afzalov, Peter Blaesse, Sampsa T. Sipilä, Juha Voipio, Kristiina Huttu
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(21)
Depolarizing and excitatory GABA actions are thought to be important in cortical development. We show here that GABA has no excitatory action on CA3 pyramidal neurons in hippocampal slices from neonatalNKCC1−/−mice that lack the Na–K–2Cl cotr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee1fa40a29ef411418bffaacdaa20ee
https://pubmed.ncbi.nlm.nih.gov/19846696
https://pubmed.ncbi.nlm.nih.gov/19846696
Autor:
Ingo Kurth, Michaela Schweizer, Jaana Tyynelä, Sampsa T. Sipilä, Linda M. Laatikainen, Aleksi Haapanen, York Rudhard, Eva Ruusuvuori, Christian A. Hübner, Moritz Hentschke, Jeppe Praetorius, Helle Hasager Damkier, Juha Voipio, Stefan Jacobs
Publikováno v:
Jacobs, S, Ruusuvuori, E, Sipilä, S T, Haapanen, A, Damkier, H, Kurth, I, Hentschke, M, Schweizer, M, Rudhard, Y, Laatikainen, L M, Tyynelä, J, Prætorius, J, Voipio, J & Hübner, C A 2008, ' Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability ', Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 1, pp. 311-6 .
Aarhus University
Aarhus University
Members of the SLC4 bicarbonate transporter family are involved in solute transport and pH homeostasis. Here we report that disrupting the Slc4a10 gene, which encodes the Na + -coupled Cl − –HCO 3 − exchanger Slc4a10 (NCBE), drastically reduces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43384f66d6fe12f8428676dd48a05cae
https://pubmed.ncbi.nlm.nih.gov/18165320
https://pubmed.ncbi.nlm.nih.gov/18165320
Autor:
Sampsa T. Sipilä, Kai Kaila
Publikováno v:
Results and Problems in Cell Differentiation ISBN: 9783540726012
University of Helsinki
University of Helsinki
Endogenous activity is a characteristic feature of developing neuronal networks. In the neonatal rat hippocampus, spontaneously occurring network events known as “Giant Depolarizing Potentials” (GDPs) are seen in vitro at a stage when GABAergic t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e42ef95755d4fc5b83afc23588cb9a8b
https://doi.org/10.1007/400_2007_033
https://doi.org/10.1007/400_2007_033
