Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sampath Sridhara"'
Autor:
Suzanne M.R. Southward, Sampath Sridhara, Bryan J. Clarke, Bonnie Ross, Morris A. Blajchman, Mark W.C. Hatton, Myron Kulzcycky
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 281:E507-E515
In the human circulation, factor VII is present in relatively low plasma concentration (0.01 μM) and has been reported to have a short half-life ( t½; 6 h). In contrast, prothrombin is present in a relatively high plasma concentration (2 μM) and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c30fa6ae4b659a824c57bb165d914d4f
https://doi.org/10.1152/ajpendo.2001.281.3.e507
https://doi.org/10.1152/ajpendo.2001.281.3.e507
Autor:
Blair J.N. Leonard, Qi Chen, Morris A. Blajchman, Frederick A. Ofosu, Sampath Sridhara, Daniel Yang, Bryan J. Clarke
Publikováno v:
Blood. 91:142-148
We have previously described a kindred with factor VII (FVII) deficiency whose members exhibited reduced procoagulant activity relative to FVII antigen concentration. In this report, the molecular genetic basis of the FVII defect has been determined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c88247134e7d75c6a76a59807d32fed6
https://doi.org/10.1182/blood.v91.1.142.142_142_148
https://doi.org/10.1182/blood.v91.1.142.142_142_148
Autor:
Qi Chen, Sampath Sridhara, Frederick A. Ofosu, Blair J.N. Leonard, Morris A. Blajchman, Daniel Yang, Bryan J. Clarke
Publikováno v:
Blood. 91:142-148
We have previously described a kindred with factor VII (FVII) deficiency whose members exhibited reduced procoagulant activity relative to FVII antigen concentration. In this report, the molecular genetic basis of the FVII defect has been determined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6bc4326065e98301a035828c640af79
https://doi.org/10.1182/blood.v91.1.142
https://doi.org/10.1182/blood.v91.1.142
Publikováno v:
American Journal of Hematology. 53:66-71
A competitive enzyme-linked immunoadsorbent assay (ELISA) technique has been developed to facilitate quantitative analysis of the earliest step in the initiation of the extrinsic pathway of coagulation, i.e., complex formation of factor VII/VIIa with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6db0f74b84e612f3c8e7886f4b5d5e2e
https://doi.org/10.1002/(sici)1096-8652(199610)53:2<66::aid-ajh2>3.0.co
https://doi.org/10.1002/(sici)1096-8652(199610)53:2<66::aid-ajh2>3.0.co
Autor:
Sampath Sridhara, Bryan J. Clarke
Publikováno v:
British Journal of Haematology. 93:445-450
The integrity of the gamma-carboxylic glutamic acid (GLA) residues of coagulation factor VII are thought to be essential for both the interaction of factor VII with its cell-surface lipoprotein receptor tissue factor and for the activated protein to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538cd6bc270ac8e756f86f6caa47a3c5
https://doi.org/10.1046/j.1365-2141.1996.5141054.x
https://doi.org/10.1046/j.1365-2141.1996.5141054.x
Autor:
Morris A. Blajchman, Harold R. Roberts, Paul Friedman, William J. Vandusen, Kirk Chu, Bryan J. Clarke, Dougald M. Monroe, Shu Huey Chaing, Sampath Sridhara, Katherine A. High
Publikováno v:
Scopus-Elsevier
Factor VII (F.VII) is a vitamin-K-dependent serine protease required in the early stages of blood coagulation. We describe here a patient with severe F.VII deficiency, with a normal plasma F.VII antigen level (452 ng/mL) and F.VII activity less than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8efd1c5ead78568be6481b7a70b5d98
https://doi.org/10.1182/blood.v83.12.3524.bloodjournal83123524
https://doi.org/10.1182/blood.v83.12.3524.bloodjournal83123524
Autor:
Frederick R. Rickles, Sampath Sridhara, Morris A. Blajchman, Bryan J. Clarke, Frederick A. Ofosu, Robert Bona
Publikováno v:
FEBS Letters. 298:206-210
The intrinsic pathway of coagulation is initiated when zymogen factor VII binds to its cell surface receptor tissue factor to form a catalytic binary complex. Both the activation of factor VII to factor VIIa and the expression of serine protease acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e340b69a22b12e7f28a66e3dfe246ef5
https://doi.org/10.1016/0014-5793(92)80058-o
https://doi.org/10.1016/0014-5793(92)80058-o
Autor:
Sampath Sridhara, Morris A. Blajchman, Bryan J. Clarke, A. Pyke, Robert F. Kelley, V. Williamson
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 3(6)
Summary. The first epidermal growth factor-like (EGF1) domain of human factor VII (FVII) is essential for binding to tissue factor (TF). We hypothesized that the previously observed increased coagulant activity of rabbit plasma (i.e. FVII) with human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25927a21ecea356413a8dc58037f1f2
https://pubmed.ncbi.nlm.nih.gov/15892860
https://pubmed.ncbi.nlm.nih.gov/15892860
Autor:
Bryan J. Clarke, Morris A. Blajchman, Frederick A. Ofosu, Robert F. Kelley, Sampath Sridhara, Blair J.N. Leonard
Publikováno v:
The Journal of biological chemistry. 275(45)
The first epidermal growth factor-like domain (EGF-1) of factor VII (FVII) provides the region of greatest contact during the interaction of FVIIa with tissue factor. To understand this interaction better, the conformation-sensitive FVII EGF-1-specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94def875dfb0176a0367f70d2c1d443f
https://pubmed.ncbi.nlm.nih.gov/10952970
https://pubmed.ncbi.nlm.nih.gov/10952970
Publikováno v:
Thrombosis research. 98(2)
To facilitate studies of the in vivo role of the extrinsic pathway of coagulation in experimental hemostasis and thrombosis, a full-length cDNA-encoding rabbit factor VII was isolated using polymerase chain reaction-mediated DNA amplification from pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda344a205086a88693ebef204e1b080
https://pubmed.ncbi.nlm.nih.gov/10713322
https://pubmed.ncbi.nlm.nih.gov/10713322