Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sampada Koranne"'
Autor:
Luke Schenck, Christopher Boyce, Derek Frank, Sampada Koranne, Heidi M. Ferguson, Neil Strotman
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 1034 (2021)
Amorphous solid dispersions (ASD) have become a well-established strategy to improve exposure for compounds with insufficient aqueous solubility. Of methods to generate ASDs, spray drying is a leading route due to its relative simplicity, availabilit
Externí odkaz:
https://doaj.org/article/7d4e18b8ee1046f1a48b98a3ac340e71
Autor:
Sampada Koranne, Christopher W. Boyce, Derek Frank, Luke Schenck, Heidi Ferguson, Neil A. Strotman
Publikováno v:
Pharmaceutics
Volume 13
Issue 7
Pharmaceutics, Vol 13, Iss 1034, p 1034 (2021)
Volume 13
Issue 7
Pharmaceutics, Vol 13, Iss 1034, p 1034 (2021)
Amorphous solid dispersions (ASD) have become a well-established strategy to improve exposure for compounds with insufficient aqueous solubility. Of methods to generate ASDs, spray drying is a leading route due to its relative simplicity, availabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12170d86e8936a58c56a441b09f02b2e
Autor:
Sampada Koranne, Eric J. Munson, Donna M. Williams, Mingyue Li, Yongchao Su, Akhilesh Bhambhani, Xingyu Lu, Rui Fang
Publikováno v:
Journal of pharmaceutical sciences. 110(3)
Biophysical and biochemical instability of therapeutic proteins in the solution state may necessitate the development of products in the solid form, due to their enhanced stability. Lyophilization is a widely used method to ensure dry state stabiliza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bad5edb9095dea2d26a097a0a09fd08
https://pubmed.ncbi.nlm.nih.gov/33249049
https://pubmed.ncbi.nlm.nih.gov/33249049
Publikováno v:
Crystal Growth & Design. 19:868-875
The stability of theophylline cocrystals composed of acidic (glutaric acid), basic (isonicotinamide), or neutral (benzamide) coformers was evaluated in the presence of several excipients. Tablets of theophylline-glutaric acid (TG) and theophylline-is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b09fa87c219c285d2b89dfb652178aa
https://doi.org/10.1021/acs.cgd.8b01430
https://doi.org/10.1021/acs.cgd.8b01430
Publikováno v:
Molecular pharmaceutics. 17(4)
Disproportionation of pioglitazone hydrochloride (PioHCl), leading to the free base formation, was observed in tablet formulations containing basic excipients such as magnesium stearate (Koranne et al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab70c18cad6c903dcda4c993a7a703a
https://pubmed.ncbi.nlm.nih.gov/32142293
https://pubmed.ncbi.nlm.nih.gov/32142293
Publikováno v:
Pharmaceutical Research. 35
To study spatial heterogeneity in phase composition when mannitol is co-lyophilized with non-crystallizing lyoprotectant, such as sucrose or trehalose. To study the influence of formulation composition and processing conditions on the extent of manni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2433cd1ee04a94ee6cc53008b86cfd
https://doi.org/10.1007/s11095-018-2499-x
https://doi.org/10.1007/s11095-018-2499-x
Autor:
Joseph F. Krzyzaniak, Anasuya Sahoo, Kapildev K. Arora, Suman Luthra, Raj Suryanarayanan, Sampada Koranne
Publikováno v:
Molecular pharmaceutics. 15(8)
Tablets containing a theophylline-glutaric acid (TG) cocrystal dissociated rapidly forming crystalline theophylline (20-30%), following storage at 40 °C/75% RH for 2 weeks. Control tablets of TG cocrystal containing no excipients were stable under t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eefa358035109f2ca653619b8c50ea86
https://pubmed.ncbi.nlm.nih.gov/29947519
https://pubmed.ncbi.nlm.nih.gov/29947519
Publikováno v:
Pharmaceutical Research. 35
(i) To investigate buffer salt crystallization and the consequent pH shifts during the freezing stage of the lyophilization of indomethacin sodium (IMCNa) in aqueous sodium phosphate buffer. (ii) To determine the effect of pH shift on the disproporti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b1728d0c8e242451a7278d21d610ca
https://doi.org/10.1007/s11095-017-2310-4
https://doi.org/10.1007/s11095-017-2310-4
Publikováno v:
Molecular pharmaceutics. 14(4)
Tablets which were binary mixtures of pioglitazone hydrochloride (PioHCl) with magnesium stearate (MgSt), croscarmellose sodium (CCS), microcrystalline cellulose, or lactose monohydrate were prepared. Two sets of experiments, using intact tablets, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0bcd25fa8075869374e00358cffbb67
https://pubmed.ncbi.nlm.nih.gov/28195490
https://pubmed.ncbi.nlm.nih.gov/28195490