Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Samora Okujeni"'
Autor:
Samora Okujeni, Ulrich Egert
Publikováno v:
eLife, Vol 8 (2019)
The spatial distribution of neurons and activity-dependent neurite outgrowth shape long-range interaction, recurrent local connectivity and the modularity in neuronal networks. We investigated how this mesoscale architecture develops by interaction o
Externí odkaz:
https://doaj.org/article/9fde87c6dfaa4c54a0b04fde1ffc1abb
Autor:
Samora Okujeni, Ulrich Egert
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
The mesoscale architecture of neuronal networks strongly influences the initiation of spontaneous activity and its pathways of propagation. Spontaneous activity has been studied extensively in networks of cultured cortical neurons that generate compl
Externí odkaz:
https://doaj.org/article/db49863341ba46c99063111cffa8a54e
Autor:
Sreedhar S Kumar, Jan Wülfing, Samora Okujeni, Joschka Boedecker, Martin Riedmiller, Ulrich Egert
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 8, p e1005054 (2016)
Driven by clinical needs and progress in neurotechnology, targeted interaction with neuronal networks is of increasing importance. Yet, the dynamics of interaction between intrinsic ongoing activity in neuronal networks and their response to stimulat
Externí odkaz:
https://doaj.org/article/e7297c58244742ab8049b0539d8d7e9e
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 12, p e1001013 (2010)
Recently evidence has accumulated that many neural networks exhibit self-organized criticality. In this state, activity is similar across temporal scales and this is beneficial with respect to information flow. If subcritical, activity can die out, i
Externí odkaz:
https://doaj.org/article/3a19de83bbc5452794cb50eaafa97b81
Autor:
Samora Okujeni, Ulrich Egert
Publikováno v:
The Journal of Neuroscience. 43:2515-2526
Numerous studies suggest that biological neuronal networks self-organize toward a critical state with stable recruitment dynamics. Individual neurons would then statistically activate exactly one further neuron during activity cascades termed neurona
Autor:
Connie Sanchez, Abdelrahman Alabsi, Per Qvist, Samora Okujeni, Simon Glerup, Jens R. Nyengaard, Ahmad Raza Khan
Publikováno v:
Al-Absi, A-R, Qvist, P, Okujeni, S, Khan, A R, Glerup, S, Sanchez, C & Nyengaard, J R 2020, ' Layers II/III of Prefrontal Cortex in Df(h22q11)/+ Mouse Model of the 22q11.2 Deletion Display Loss of Parvalbumin Interneurons and Modulation of Neuronal Morphology and Excitability ', Molecular Neurobiology, vol. 57, no. 12, pp. 4978–4988 . https://doi.org/10.1007/s12035-020-02067-1
The 22q11.2 deletion has been identified as a risk factor for multiple neurodevelopmental disorders. Behavioral and cognitive impairments are common among carriers of the 22q11.2 deletion. Parvalbumin expressing (PV+) interneurons provide perisomatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6902b0563dba358a9759ba1115248707
https://pure.au.dk/portal/da/publications/layers-iiiii-of-prefrontal-cortex-in-dfh22q11-mouse-model-of-the-22q112-deletion-display-loss-of-parvalbumin-interneurons-and-modulation-of-neuronal-morphology-and-excitability(9e0377dc-0c58-469c-a4a6-6f09ef4a8d21).html
https://pure.au.dk/portal/da/publications/layers-iiiii-of-prefrontal-cortex-in-dfh22q11-mouse-model-of-the-22q112-deletion-display-loss-of-parvalbumin-interneurons-and-modulation-of-neuronal-morphology-and-excitability(9e0377dc-0c58-469c-a4a6-6f09ef4a8d21).html
Publikováno v:
The Journal of Neuroscience. 37:3972-3987
Spontaneous activity in the absence of external input, including propagating waves of activity, is a robust feature of neuronal networksin vivoandin vitro. The neurophysiological and anatomical requirements for initiation and persistence of such acti
Autor:
Samora Okujeni, Ulrich Egert
Publikováno v:
Frontiers in Cellular Neuroscience. 12
Autor:
Antje Kilias, Maria Asplund, Stefanie Heizmann, Ulrich Egert, Christian Boehler, Samora Okujeni, Patrick Ruther
Publikováno v:
NER
Penetrating microelectrode probes offer the opportunity to precisely monitor neuronal signals over several months. After the experimental end point, histological methods are used to analyze the tissue and to correlate recorded signals to histological