Zobrazeno 1 - 10
of 366
pro vyhledávání: '"Sammer Yousuf"'
Autor:
Bekri Melka Abdo, Bizuayehu Tesfaye Asfaw, M. Iqbal Choudhary, Sammer Yousuf, Wendawek Abebe Mengesha, Solomon Abate Mekonnen
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36818- (2024)
Several strains of Leishmania parasite are involved in the occurrence of leishmaniasis infections, which makes its prevention and treatment very challenging. Currently, all forms of leishmaniasis are being treated with chemical drugs, which have limi
Externí odkaz:
https://doaj.org/article/a89af9e889c04b49a2ea876322d8dc90
Autor:
Rubina Siddiqui, Sana Shamim, Shamim Akhter, Samia Kausar, Sammer Yousuf, Ataf Ali Altaf, Zafar Saeed Saify, Fuad Ameen
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35122- (2024)
Inflammation is one of the pertinent responses of the body, depending mainly on the process and factors involved in combating the oxidative species produced either by any infection or failure of the antioxidant pathways. In search of new compounds to
Externí odkaz:
https://doaj.org/article/07be708e77fe4f2abcc1866412a9a3b4
Publikováno v:
IUCrJ, Vol 11, Iss 2, Pp 224-236 (2024)
Leishmaniasis is a neglected parasitic tropical disease with numerous clinical manifestations. One of the causative agents of cutaneous leishmaniasis (CL) is Leishmania tropica (L. tropica) known for causing ulcerative lesions on the skin. The advers
Externí odkaz:
https://doaj.org/article/296690fbdbfa4b8c9ec943c27ac715db
Autor:
Mohammad Shahidul Islam, Abdullah Mohammed Al-Majid, Essam Nageh Sholkamy, Assem Barakat, Maurizio Viale, Paola Menichini, Andrea Speciale, Fabrizio Loiacono, Mohammad Azam, Ved Prakash Verma, Sammer Yousuf, Mohamed Teleb
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-23 (2023)
Abstract Recently, cancer research protocols have introduced clinical-stage spirooxindole-based MDM2 inhibitors. However, several studies reported tumor resistance to the treatment. This directed efforts to invest in designing various combinatorial l
Externí odkaz:
https://doaj.org/article/3163e75f3ed94e9b89596f628803db7b
Autor:
Abdulmajeed Abdullah Alayyaf, Assem Barakat, Abdullah Mohammed Al-Majid, M. Ali, Sammer Yousuf, Matti Haukka, Ayman El-Faham, Saied M. Soliman, Mohamed S. Nafie
Publikováno v:
Crystals, Vol 13, Iss 10, p 1472 (2023)
The synthesis and X-ray structure analysis of the new [PdLCl2]*0.5 CH2Cl2 complex where L is hydrazono-s-triazine di-morpholine derivative, were presented. In the neutral inner sphere of this complex, the organic ligand L is acting as a NN-bidentate
Externí odkaz:
https://doaj.org/article/d3ffd623dedd4d13948f8c15811457fb
Autor:
Saeed Alshahrani, Abdullah Mohammed Al-Majid, Abdullah Saleh Alamary, M. Ali, Mezna Saleh Altowyan, Mar Ríos-Gutiérrez, Sammer Yousuf, Assem Barakat
Publikováno v:
Molecules, Vol 28, Iss 19, p 6976 (2023)
A new series of spirooxindoles based on benzimidazole, triazole, and isatin moieties were synthesized via a [3+2] cycloaddition reaction protocol in one step. The single X-ray crystal structure of the intermediate triazole-benzimidazole 4 was solved.
Externí odkaz:
https://doaj.org/article/b2fa485cb2344e74b1ac941ebcbb452d
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 76, Iss 3, Pp 294-297 (2020)
The title compound, C20H36O2·CH3OH [systematic name: (3S)-4-[(S)-3-hydroxy-3-methylpent-4-en-1-yl]-3,4a,8,8-tetramethyldecahydronaphthalen-3-ol methanol monosolvate], is a methanol solvate of sclareol, a diterpene oil isolated from the medicinally i
Externí odkaz:
https://doaj.org/article/91134caf16844f4f8ad5cc8695143b38
Autor:
M. Ali, Assem Barakat, Ayman El-Faham, Hessa H. Al-Rasheed, Kholoud Dahlous, Abdullah Mohammed Al-Majid, Anamika Sharma, Sammer Yousuf, Mehar Sanam, Zaheer Ul-Haq, M. Iqbal Choudhary, Beatriz G. de la Torre, Fernando Albericio
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 692-701 (2020)
A new series of thiobarbituric (thiopyrimidine trione) enamine derivatives and its analogues barbituric acid derivatives was synthesised, characterised, and screen for in vitro evaluation of α-glucosidase enzyme inhibition and anti-glycation activit
Externí odkaz:
https://doaj.org/article/1416f61c2afb480495d7cf060166b1b2
Publikováno v:
IUCrJ, Vol 7, Iss 1, Pp 105-112 (2020)
Co-crystallization is a phenomenon widely employed to enhance the physio-chemical and biological properties of active pharmaceutical ingredients (APIs). Exemestane, or 6-methylideneandrosta-1,4-diene-3,17-dione, is an anabolic steroid used as an irre
Externí odkaz:
https://doaj.org/article/bb56bd087a034c59b7a7f10fb15c5008
Autor:
Saira Bano, Memoona Bibi, Saba Farooq, Humaira Zafar, Muniza Shaikh, Behram Khan Khoso, Sammer Yousuf, M Iqbal Choudhary
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0274543 (2022)
Cutaneous leishmaniasis (CL) is a major health problem in over 98 countries of the world, including Pakistan. The current treatments are associated with a number of adverse effects and availability problem of drugs. Therefore, there is an urgent need
Externí odkaz:
https://doaj.org/article/9d0d54fdc607477c94f4d4819c89e56b