Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Samith Thomas Kochuparambil"'
Autor:
Padmanee Sharma, Michael Krainer, Fred Saad, Daniel Castellano, Jens Bedke, Mariusz Kwiatkowski, Akash Patnaik, Giuseppe Procopio, Pawel Wiechno, Samith Thomas Kochuparambil, Christian Thomas, Jose Angel Arranz Arija, Steven L. McCune, Steinbjorn Hansen, Gedske Daugaard, Neha P. Amin, Yumeng Wang, Justin M. David, Russell Kent Pachynski
Publikováno v:
Journal of Clinical Oncology. 41:22-22
22 Background: In preliminary analyses from the randomized phase 2, open-label CheckMate 650 trial, nivolumab (NIVO) 1 mg/kg (N1) plus ipilimumab (IPI) 3 mg/kg (I3) Q3W × 4 doses showed clinical activity in patients (pts) with post-chemotherapy (pos
Autor:
David Cognetti, Joseph Curry, Jennifer Johnson, Frank E. Mott, Mary J. Fidler, John Campana, Nilesh R. Vasan, Mohammad Razaq, Kerstin M. Stenson, Samith Thomas Kochuparambil, Ann M. Gillenwater, Darren McDonald
Publikováno v:
Journal of Clinical Oncology. 36:6039-6039
6039Background: Patients with recurrent HNSCC (rHNSCC) have limited therapeutic options and poor prognosis. We report promising results of a Phase 2a trial of photoimmunotherapy (PIT) for the treat...
Autor:
Anand Jillella, Michael Craig, Mehdi Hamadani, Salman Osman, Scot C. Remick, Laura F. Gibson, Farrukh T. Awan, Jame Abraham, Samith Thomas Kochuparambil
Publikováno v:
Bone Marrow Transplantation. 47:146-148
Impact of response to thalidomide-, lenalidomide- or bortezomib- containing induction therapy on the outcomes of multiple myeloma patients undergoing autologous transplantation
Autor:
Aaron Cumpston, Mehdi Hamadani, Michael Craig, F. T. Awan, Sonia Leadmon, Kathy Watkins, David L. DeRemer, Anand Jillella, Samith Thomas Kochuparambil, D E Falconer
Publikováno v:
Bone marrow transplantation. 48(10)
Studies comparing the efficacy and cost of stem cell mobilization with intermediate-dose CY (ID-CY) and G-CSF against plerixafor and G-CSF, specifically in multiple myeloma (MM) patients treated in the novel therapy era, are not available. Eighty-eig
Autor:
Ahmad Al-Azayzih, Shuaib Mohammad, Payaningal R. Somanath, Belal Al-Husein, Anna Goc, Samith Thomas Kochuparambil
Publikováno v:
BMC Cancer
BMC Cancer, Vol 12, Iss 1, p 409 (2012)
BMC Cancer, Vol 12, Iss 1, p 409 (2012)
Background Recent studies suggest the potential benefits of statins as anti-cancer agents. Mechanisms by which statins induce apoptosis in cancer cells are not clear. We previously showed that simvastatin inhibit prostate cancer cell functions and tu
Autor:
Belal Al-Husein, Anna Goc, Martha K. Terris, Payaningal R. Somanath, Samith Thomas Kochuparambil
Publikováno v:
Journal of Urology. 185
Autor:
Anna Goc, Junxiu Liu, Payaningal R. Somanath, Samith Thomas Kochuparambil, Warren W D Heston, Belal Al-Husein
Publikováno v:
International Journal of Oncology. 38
PI3 kinase (PI3K), Akt and MAP kinase (MAPK) pathways are central to many classical signaling cascades and are often de-regulated in many cancers. Due to this, inhibitors for a number of key signaling molecules in these pathways such as PI3K, Akt, mT
Autor:
Samith Thomas Kochuparambil, Sahar Soliman, Belal Al-Husein, Payaningal R. Somanath, Anna Goc
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 336(2)
Prostate cancer is the second-leading cause of cancer-associated death among men in the United States. There has been renewed interest in the potential therapeutic benefits of statins for cancer. Simvastatin, a widely used generic drug for preventing
Autor:
Anand Jillella, Sonia Leadmon, Michael Craig, Aaron Cumpston, Vamsi Kota, Kathy Watkins, Mehdi Hamadani, David L. DeRemer, Samith Thomas Kochuparambil, Jeremy Pantin, Farrukh T. Awan
Publikováno v:
Biology of Blood and Marrow Transplantation. 19(2):S182-S183
Publikováno v:
Biology of Blood and Marrow Transplantation. 17(2):S208-S209